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Multiplex BCR cDNA libraries

For this tutorial we will use the data published in the following article:

Aizik L, Dror Y, Taussig D, Barzel A, Carmi Y, Wine Y. Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues. Front Immunol. 2021 Jul 19;12:705381. doi: 10.3389/fimmu.2021.705381. PMID: 34349765; PMCID: PMC8327180.

Experiment setting

BALB/C mice were injected subcutaneously into mammary fat-pad number five with 2×105 4T1 cells suspended in 30 µl of DMEM (Gibco, Thermo Fisher Scientific). The induced tumors were monitored by measuring their size twice a week using calipers. After 23 days, mice were sacrificed, and B cells were isolated from four tissue types, namely, bone marrow, blood, DLNs, and tumors. For the control mice, three tissue types were collected - bone marrow, blood, and lymph nodes. Lymphocytes were isolated from every sample. For all tissues, cells were then incubated with a mixture of anti-IgG, anti-IgM, anti-CD138 magnetic beads. Later, total RNA was isolated following by first-strand cDNA synthesis using SuperScript™ III First-Strand Synthesis System with 200 ng RNA as the template and Oligo (dT) primers. After cDNA synthesis, PCR amplification of the variable heavy Ig genes was performed using a set of 19 forward primers with the gene-specific regions annealing to framework 1 of the VDJ-region and two reverse primers with the gene-specific region binding to the IgG and IgM constant regions. Recovered DNA products from the first PCR was applied to a second PCR amplification to attach Illumina adaptors to the amplified VH genes using the primer extension method. Technical replicates (two per sample) of BCR-Seq libraries were prepared based on cDNA from each mouse/tissue. cDNA was split, and library preparation was performed in parallel with different Illumina indices as described above. cDNA libraries were subjected to NGS on the MiSeq platform with the reagent kit V3 2 × 300 bp paired-end (Illumina).

Show primers
# PCR1 Forward primers
# Primers include step-out(glue) sequence and gene specific region

m-VH-glue-Fw1   CCCTCCTTTAATTCCCGAKGTRMAGCTTCAGGAGTC
m-VH-glue-Fw2   CCCTCCTTTAATTCCCGAGGTBCAGCTBCAGCAGTC
m-VH-glue-Fw3   CCCTCCTTTAATTCCCCAGGTGCAGCTGAAGSASTC
m-VH-glue-Fw4   CCCTCCTTTAATTCCCGAGGTCCARCTGCAACARTC
m-VH-glue-Fw5   CCCTCCTTTAATTCCCCAGGTYCAGCTBCAGCARTC
m-VH-glue-Fw6   CCCTCCTTTAATTCCCCAGGTYCARCTGCAGCAGTC
m-VH-glue-Fw7   CCCTCCTTTAATTCCCCAGGTCCACGTGAAGCAGTC
m-VH-glue-Fw8   CCCTCCTTTAATTCCCGAGGTGAASSTGGTGGAATC
m-VH-glue-Fw9   CCCTCCTTTAATTCCCGAVGTGAWGYTGGTGGAGTC
m-VH-glue-Fw10  CCCTCCTTTAATTCCCGAGGTGCAGSKGGTGGAGTC
m-VH-glue-Fw11  CCCTCCTTTAATTCCCGAKGTGCAMCTGGTGGAGTC
m-VH-glue-Fw12  CCCTCCTTTAATTCCCGAGGTGAAGCTGATGGARTC
m-VH-glue-Fw13  CCCTCCTTTAATTCCCGAGGTGCARCTTGTTGAGTC
m-VH-glue-Fw14  CCCTCCTTTAATTCCCGARGTRAAGCTTCTCGAGTC
m-VH-glue-Fw15  CCCTCCTTTAATTCCCGAAGTGAARSTTGAGGAGTC
m-VH-glue-Fw16  CCCTCCTTTAATTCCCCAGGTTACTCTRAAAGWGTSTG
m-VH-glue-Fw17  CCCTCCTTTAATTCCCCAGGTCCAACTVCAGCARCC
m-VH-glue-Fw18  CCCTCCTTTAATTCCCGATGTGAACTTGGAAGTGTC
m-VH-glue-Fw19  CCCTCCTTTAATTCCCGAGGTGAAGGTCATCGAGTC

# PCR1 Reverse primers
# Primers inglude step-out(glue) sequence and gene specific region

m-IgMC-BC-glue-REV      GAGGAGAGAGAGAGAGCGTGATCGAGGGGGAAGACATTTGGG
m-IgGall-BC-glue-REV    GAGGAGAGAGAGAGAGACATCGCCARKGGATAGACHGATGGG

# PCR2 Forward primer
# Primer ingludes Universal trueSeq Illumina adaptor and glue sequence from PCR1 forward primers

PE-IgALL-Univ-FW    AATGATACGGCGACCACCGAGATCTACACTCTTTCCCTACACGACGCTCTTCCGATCTNNNNCCCTCCTTTAATTCCC

# PCR2 Reverse primer
# Primer ingludes Universal trueSeq Illumina adaptor and glue sequence from PCR1 reverse primers

YW23X_PE-Idx-REV    CAAGCAGAAGACGGCATACGAGATNNNNNNGTGACTGGAGTTCAGACGTGTGCTCTTCCGATCTNNNNGAGGAGAGAGAGAGAG

All data may be downloaded using the script bellow.

Use aria2c for efficient download of the full dataset with the proper filenames:

download.sh
mkdir -p raw
aria2c -c -s 16 -x 16 -k 1M -j 8 -i download-list.txt
download-list.txt
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Blood_S2_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Blood_S2_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Blood_S6_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Blood_S6_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_BM_S4_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_BM_S4_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_BM_S8_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_BM_S8_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_DLN_S3_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_DLN_S3_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_DLN_S7_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_DLN_S7_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Tumor_S1_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Tumor_S1_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica1_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Tumor_S5_L001_R1_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M1_4T1_Tumor_S5_L001_R2_001_B3.1.fastq.gz
  out=raw/M1_4T1_replica2_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Blood_S2_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica1_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Blood_S2_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica1_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Blood_S6_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica2_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Blood_S6_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica2_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_BM_S4_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica1_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_BM_S4_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica1_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_BM_S8_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica2_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_BM_S8_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica2_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_DLN_S3_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica1_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_DLN_S3_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica1_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_DLN_S7_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica2_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_DLN_S7_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica2_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Tumor_S1_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica1_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Tumor_S1_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica1_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Tumor_S5_L001_R1_001.fastq.gz
  out=raw/M2_4T1_replica2_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M2_4T1_Tumor_S5_L001_R2_001.fastq.gz
  out=raw/M2_4T1_replica2_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Blood_S10_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica1_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Blood_S10_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica1_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Blood_S9_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica2_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Blood_S9_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica2_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_BM_S7_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica1_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_BM_S7_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica1_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_BM_S8_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica2_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_BM_S8_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica2_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_DLN_S11_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica1_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_DLN_S11_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica1_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_DLN_S12_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica2_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_DLN_S12_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica2_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Tumor_S13_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica1_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Tumor_S13_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica1_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Tumor_S14_L001_R1_001.fastq.gz
  out=raw/M3_4T1_replica2_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M3_4T1_Tumor_S14_L001_R2_001.fastq.gz
  out=raw/M3_4T1_replica2_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Blood_S2_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica1_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Blood_S2_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica1_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Blood_S7_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica2_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Blood_S7_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica2_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_BM_S10_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica1_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_BM_S10_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica1_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_BM_S5_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica2_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_BM_S5_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica2_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_DLN_S4_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica1_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_DLN_S4_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica1_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_DLN_S9_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica2_DLN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_DLN_S9_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica2_DLN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Tumor_S1_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica1_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Tumor_S1_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica1_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Tumor_S6_L001_R1_001.fastq.gz
  out=raw/M4_4T1_replica2_Tumor_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/M4_4T1_Tumor_S6_L001_R2_001.fastq.gz
  out=raw/M4_4T1_replica2_Tumor_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_Blood_S5_L001_R1_001.fastq.gz
  out=raw/N1_control_replica1_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_Blood_S5_L001_R2_001.fastq.gz
  out=raw/N1_control_replica1_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_Blood_S6_L001_R1_001.fastq.gz
  out=raw/N1_control_replica2_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_Blood_S6_L001_R2_001.fastq.gz
  out=raw/N1_control_replica2_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_BM_S1_L001_R1_001.fastq.gz
  out=raw/N1_control_replica1_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_BM_S1_L001_R2_001.fastq.gz
  out=raw/N1_control_replica1_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_BM_S2_L001_R1_001.fastq.gz
  out=raw/N1_control_replica2_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_BM_S2_L001_R2_001.fastq.gz
  out=raw/N1_control_replica2_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_LN_S3_L001_R1_001.fastq.gz
  out=raw/N1_control_replica1_LN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_LN_S3_L001_R2_001.fastq.gz
  out=raw/N1_control_replica1_LN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_LN_S4_L001_R1_001.fastq.gz
  out=raw/N1_control_replica2_LN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N1_control_LN_S4_L001_R2_001.fastq.gz
  out=raw/N1_control_replica2_LN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_Blood_S5_L001_R1_001.fastq.gz
  out=raw/N2_control_replica1_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_Blood_S5_L001_R2_001.fastq.gz
  out=raw/N2_control_replica1_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_Blood_S6_L001_R1_001.fastq.gz
  out=raw/N2_control_replica2_Blood_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_Blood_S6_L001_R2_001.fastq.gz
  out=raw/N2_control_replica2_Blood_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_BM_S1_L001_R1_001.fastq.gz
  out=raw/N2_control_replica1_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_BM_S1_L001_R2_001.fastq.gz
  out=raw/N2_control_replica1_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_BM_S2_L001_R1_001.fastq.gz
  out=raw/N2_control_replica2_BM_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_BM_S2_L001_R2_001.fastq.gz
  out=raw/N2_control_replica2_BM_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_LN_S3_L001_R1_001.fastq.gz
  out=raw/N2_control_replica1_LN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_LN_S3_L001_R2_001.fastq.gz
  out=raw/N2_control_replica1_LN_R2.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_LN_S4_L001_R1_001.fastq.gz
  out=raw/N2_control_replica2_LN_R1.fastq.gz
https://cdn.milaboratory.com/data/PRJNA699402/N2_control_LN_S4_L001_R2_001.fastq.gz
  out=raw/N2_control_replica2_LN_R2.fastq.gz

One command Solution

The easiest way to obtain clonotype tables for this type of data is to use a universal mixcr analyze command. This is a BCR data, so we will use a preset called generic-amplicon.

The exact command for a single sample you can see bellow:

mixcr analyze generic-amplicon \
    --species mmu \
    --rna \
    --rigid-left-alignment-boundary \
    --rigid-right-alignment-boundary \
    --tagPattern ^N{4}ccctcctttaattccc{21}(R1:*)\^N{4}gaggagagagagagagN{26}(R2:*) \
    --assemble-clonotypes-by {CDR1Begin:FR4End} \
    raw/M1_4T1_replica1_Blood_R1.fastq.gz \
    raw/M1_4T1_replica1_Blood_R2.fastq.gz \
    results/M1_4T1_replica1_Blood

The meaning of these options is the following.

--species
is set to mmu for Mus Musculus
--rna
corresponds to VTranscriptWithout5UTRWithP alignment feature for V-gene (see Gene features and anchor points for details)
--rigid-left-alignment-boundary
leads to a global alignment algorithms to align the left bound of V gene because primer sequences are trimmed with tagPattern. This options sets -OvParameters.parameters.floatingLeftBound=false for mixcr align step of the pipeline.
--rigid-right-alignment-boundary
sets -OjParameters.parameters.loatingRightBound=false -OcParameters.parameters.floatingRightBound=true for mixcr align step of the pipeline to ensure global alignment on the right bound of bot J and C gene. Global alignment should be used when primer sequences have been trimmed.
--tag-pattern ^N{4}ccctcctttaattcccN{22}(R2:*)\^N{4}gaggagagagagagagN{26}(R1:*)
This tag-pattern trims all adapter and primer sequences from both reads.
--assemble-clonotypes-by {CDR1Begin:FR4End}
sets -OassemblingFeatures={CDR1Begin:FR4End} for mixcr assemble step. We extend the assembling feature to start from CDR1. That is because this is BCR data, where hypermutations occur throughout V gene, and we want to capture as much as we can.
raw/M1_4T1_replica1_Blood_R1.fastq.gz raw/M1_4T1_replica1_Blood_R2.fastq.gz results/M1_4T1_replica1_Blood
Finally, we provide the names of input files and an output prefix:

Running the command above will generate the following files:

> ls result/

# human-readable reports 
M1_4T1_replica1_Blood.align.report.txt
M1_4T1_replica1_Blood.align.report.json
M1_4T1_replica1_Blood.assemble.report.txt
M1_4T1_replica1_Blood.assemble.report.json

# raw alignments (highly compressed binary file)
M1_4T1_replica1_Blood.vdjca

# CDR3 clonotypes (highly compressed binary file)
M1_4T1_replica1_Blood.clns

# CDR3 clonotypes exported in tab-delimited txt
M1_4T1_replica1_Blood.clones.tsv

While .clns file holds all data and is used for downstream analysis using mixcr postanalisis, the output .tsv clonotype table will contain exhaustive information about each clonotype as well:

See first 100 records from FebControl1.clones.IGH.tsv clonotype table
cloneId cloneCount cloneFraction targetSequences targetQualities allVHitsWithScore allDHitsWithScore allJHitsWithScore allCHitsWithScore allVAlignments allDAlignments allJAlignments allCAlignments nSeqFR1 minQualFR1 nSeqCDR1 minQualCDR1 nSeqFR2 minQualFR2 nSeqCDR2 minQualCDR2 nSeqFR3 minQualFR3 nSeqCDR3 minQualCDR3 nSeqFR4 minQualFR4 aaSeqFR1 aaSeqCDR1 aaSeqFR2 aaSeqCDR2 aaSeqFR3 aaSeqCDR3 aaSeqFR4 refPoints
0 17236 0.0390159 GGGTTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGAGATGGTAACTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV7-3*00(2605.7) IGHD2-8*00(30) IGHJ2*00(490) IGHM*00(64.8) 232 460 481 0 228 SA234GSG282AST414CSG415AST457G 2135.0 25 31 51 228 234 30.0 19 68 68 234 283 490.0 nan nan nan GGGTTCACCTTCACTGATTACTAC 38
1 12388 0.0280418 GGCTTCAACATTAAAGACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATACTAAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAACTGGGACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV14-3*00(2523.9) IGHD4-1*00(30) IGHJ1*00(481) IGHM*00(64.8) 232 449 471 0 217 SA247GSC338AST369ASA433G 2054.0 14 20 33 217 223 30.0 22 73 73 223 274 SA45G 481.0 nan nan nan GGCTTCAACATTAAAGACACCTAT 38
2 6655 0.0150644 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACATTACTACGGTAGTAGCTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2714.4) IGHD1-1*00(85) IGHJ2*00(490) IGHM*00(64.8) 232 451 471 0 219 2190.0 26 43 69 220 237 85.0 19 68 68 237 286 490.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38
3 4321 0.00978113 GGGTTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGAGATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV7-3*00(2605.3) nan IGHJ2*00(480) IGHM*00(64.9) 232 460 481 0 228 SA234GSG282AST414CSG415AST457G 2135.0 nan 20 68 68 232 280 480.0 nan nan nan GGGTTCACCTTCACTGATTACTAC 38 ATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTT 38 ATTAGAAACAAAGCTAATGGTTACACAACA 38 GAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTAC 38
4 3599 0.00814679 GGATTCACTTTCAGTAGCTTTGGAATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATACATTAGTAGTGGCAGTAGTACCATCTACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGAAATGGGGATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-17*00(2477.8) nan IGHJ4*00(480) IGHG2C*00(62.6) 232 450 471 0 218 SG247ASA248GSA251TST300CSG379CSG414A 2006.0 nan 26 74 74 226 274 480.0 nan nan nan GGATTCACTTTCAGTAGCTTTGGA 38 ATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATAC 38 ATTAGTAGTGGCAGTAGTACCATC 38 TACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTAC 38
5 2414 0.00546439 GGCTACACATTTACTGACCATATTATGAATTGGGTAAAAAAGAGGCCTGGACAGGGCCTTGAGTGGATTGGAAGGATTTATCCAGTAAGTGGTGAAACTAACTACAATCAAAAGTTCATGGGCAAGGCCACATTCTCTGTAGACCGGTCCTCCAGCACAGTGTACATGGTGTTGAACAGCCTGACATCTGAGGACCCTGCTGTCTATTACTGTGGAACTGGGACGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-11*00(2697.1) IGHD4-1*00(40) IGHJ2*00(460) IGHM*00(64.9) 232 449 471 0 217 2170.0 15 23 33 217 225 40.0 22 68 68 225 271 460.0 nan nan nan GGCTACACATTTACTGACCATATT 38
6 2409 0.00545308 GGGTTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGAGATGGGACGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV7-3*00(2605.2) IGHD4-1*00(30) IGHJ2*00(460) IGHM*00(64.8) 232 460 481 0 228 SA234GSG282AST414CSG415AST457G 2135.0 17 23 33 228 234 30.0 22 68 68 234 280 460.0 nan nan nan GGGTTCACCTTCACTGATTACTAC 38
7 2378 0.0053829 GGATACACATTCACTAGCTATGTTATGCACTGGGTGAAGCAGAAGCCTGGGCAGGGCCTTGAGTGGATTGGATATATTAATCCTTACAATGATGGTACTAAGTACAATGAGAAGTTCAAAGGCAAGGCCACACTGACTTCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTACTGTGCAACTGGGTATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-83*00(1915.8) IGHD4-1*00(25) IGHJ4*00(550) IGHM*00(64.8) 182 399 421 0 217 SG197ASA198GSC202TST203GSA204TSC205TSA233CSG254TSG256TST260ASG266TSG267ASA268CSG270ASG273ASA275GSA276GST281ASC283GSG301ASG320TSC327ASC350GSA367CSA382GST390A 1416.0 15 20 33 217 222 25.0 19 74 74 222 277 550.0 nan nan nan GGATACACATTCACTAGCTATGTT 38
8 2351 0.00532179 GGATTCACTTTCAGTAGCTATGCCATGTCTTGGGTTCGCCAGACTCCGGAGAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGACATTACTACGGTAGTAGCTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-600(2543.7),IGHV5-900(2541.9) IGHD1-1*00(85) IGHJ2*00(490) IGHM*00(64.9) 232 451 471 0 219 SG254CSA279GSC282GSA416GSA429G 2045.0;232 451 471 0 219 SA253GSG313ASG322ASA325TST354GST433A 2016.0 26 43 69 220 237 85.0 19 68 68 237 286
9 2128 0.004817 GGATTCACTTTCAGTAGCTATGCCATGTCTTGGGTTCGCCAGACTCCGGAGAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGTCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGACATTACTACGGTAGTAGCTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-900(2568.8),IGHV5-600(2513.8) IGHD1-1*00(85) IGHJ2*00(490) IGHM*00(64.7) 232 451 471 0 219 SA253GSG313ASG322ASA325TST433A 2045.0;232 451 471 0 219 SG254CSA279GSC282GSG354TSA416GSA429G 2016.0 26 43 69 220 237 85.0 19 68 68 237 286
10 1991 0.00450688 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTATGGTGATGCTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGACTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGACCCTATGATTACGACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-1900(1634.1),IGHV1-2200(1601.9) IGHD2-4*00(55) IGHJ4*00(510) IGHG2C*00(38.7) 232 451 471 0 219 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSC321TSG326ASA328GST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC426TSA432CSG433A 1378.0;232 451 471 0 219 SA234CSC249TSC252TSA253GSA254CSC255TSC276TSG281CSC288TST291AST304GSA305TSA311GSC312TSC313ASA316TSA319TSG326ASA328GST364ASA373GSG378ASC396TSG402ASC405TSC406GSG407CSC411ASG420TSA432CSG433A 1291.0 21 32 51 221 232 55.0 23 74 74 232 283
11 1819 0.00411754 GGGTTTTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTAATATGGGCTGGTGGAAGCACAAATTATAATTCGGCTCTCATGTCCAGACTGAGCATCAGCAAAGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGAACTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-9*00(2581) nan IGHJ2*00(410) IGHM*00(64.7) 232 446 469 0 214 SG259CSG314CSA339G 2053.0 nan 27 68 68 218 259 410.0 nan nan nan GGGTTTTCATTAACCAGCTATGGT 38 GTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTA 38 ATATGGGCTGGTGGAAGCACA 38 AATTATAATTCGGCTCTCATGTCCAGACTGAGCATCAGCAAAGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTAC 38
12 1793 0.00405868 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACAATGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATACTATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1480.1) IGHD2-800(45),IGHD2-700(40) IGHJ2*00(480) IGHM*00(64.8) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1301.0 20 29 51 220 229 45.0;20 28 51 220 228 40.0 20 68 68 229 277
13 1744 0.00394776 GGATACACATTCACTGACTATGTTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTGGAAGTGGTAGTACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAACACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATGGGAATTACGAAGGGGCGATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-7700(2286.1),IGHV1-8100(2235) IGHD2-400(35),IGHD2-700(30) IGHJ4*00(540) IGHG2C*00(55.1) 232 452 471 0 220 SC234ASC240ASC252TST253GSA254TSA260GSG276ASC277ASA304GSG310TSG311ASG386ASA432G 1823.0;232 452 471 0 220 SC234ASC240ASA246TSA247GSG248ASG254TSA316GSA326GSG386ASG393CSG400CSC406A 1852.0 26 33 51 224 231 35.0;27 33 51 225 231 30.0
14 1674 0.00378931 GGCTACACATTCAGTAGCTACTGGATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAGATTTTACCTGGAAGTGGTAGTACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCCGTCTATTACTGTGCCTCGACAGCTCGGGCTACGAGAGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-9*00(2502.8) IGHD3-100(75),IGHD3-200(67) IGHJ4*00(460) IGHG2C*00(61.6) 232 447 471 0 215 SC245GSG247ASA418TSA433G 2034.0 20 35 51 219 234 75.0;14 33 48 215 234 SA16CSA25G 67.0 28 74 74 237 283
15 1615 0.00365576 GGCTACACCTTCACTACCTATCCAATAGAGTGGATGAAGCAGAATCATGGGAAGAGCCTAGAGTGGATTGGAAATTTTCATCCTTACAATGATGATACTAAGTACAATGAAAAATTCAAGGGCAAGGCCAAATTGACTGTAGAAAAATCCTCTAGCACAGTCTACTTGGAGCTCAGCCGATTAACATCTGATGACTCTGCTGTTTATTACTGTGCAAGGGGGGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-47*00(2513.3) nan IGHJ3*00(450) IGHM*00(64.9) 232 451 471 0 219 ST255ASA282GSG345ASC362A 2074.0 nan 23 68 68 223 268 450.0 nan nan nan GGCTACACCTTCACTACCTATCCA 38 ATAGAGTGGATGAAGCAGAATCATGGGAAGAGCCTAGAGTGGATTGGAAAT 38 TTTCATCCTTACAATGATGATACT 38 AAGTACAATGAAAAATTCAAGGGCAAGGCCAAATTGACTGTAGAAAAATCCTCTAGCACAGTCTACTTGGAGCTCAGCCGATTAACATCTGATGACTCTGCTGTTTATTAC 38
16 1570 0.00355389 GGATTCACCTTCAATACCTACGCCATGAACTGGGTCCGCCAGGCTCCAGGAAAGGGTTTGGAATGGGTTGCTCGCATAAGAAGTAAAAGTAATAATTATGCAACATATTATGCCGATTCAGTGAAAGACAGGTTCACCATCTCCAGAGATGATTCACAAAGCATGCTCTATCTGCAAATGAACAACTTGAAAACTGAGGACACAGCCATGTATTACTGTGTGAGCGGGGGTAACTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV10-1*00(2679.8) nan IGHJ1*00(512) IGHG2C*00(58.2) 232 456 477 0 224 SG239CSA363GSG388C 2153.0 nan 16 73 73 229 286 SG19ASA45G 512.0 nan nan nan GGATTCACCTTCAATACCTACGCC 38 ATGAACTGGGTCCGCCAGGCTCCAGGAAAGGGTTTGGAATGGGTTGCTCGC 38 ATAAGAAGTAAAAGTAATAATTATGCAACA 38 TATTATGCCGATTCAGTGAAAGACAGGTTCACCATCTCCAGAGATGATTCACAAAGCATGCTCTATCTGCAAATGAACAACTTGAAAACTGAGGACACAGCCATGTATTAC 38
17 1544 0.00349504 GGATTCACTTTCAGTGACTATTACATGTATTGGGTTCGCCAGACTCCGGAAAAGAGGCTGGAGTGGGTCGCAACCATTAGTGATGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACAACCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGTTATAGGTACCTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-400(2416.2),IGHV5-600(2387.6) IGHD5-100(35),IGHD5-200(30),IGHD5-3*00(30) IGHJ3*00(420) IGHG2C*00(48.7) 232 450 471 0 218 SA247GSG248ASG253TSC254ASC260ASA344GSA348GSC354GSC409ASA410G 1890.0;232 450 471 0 218 SA247GSG248ASG253TSG254ASC260ASA279GSC282ASA313GSG314ASC389A 1890.0 1 8 30 221 228 35.0;1 7 30 221 227 30.0;1
18 1332 0.00301515 GAATACGAATTCCCTTCCCATGACATGTCTTGGGTCCGCAAGACTCCGGAGAAGAGGCTGGAGTTGGTCGCAGCCATTAATAGTGATGGTGGTAGCACCTACTATCCAGACACCATGGAGAGACGATTCATCATCTCCAGAGACAATACCAAGAAGACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACAGCCTTGTATTACTGTGCAAGACACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-2*00(2737.2) nan IGHJ2*00(480) IGHM*00(64.8) 232 453 473 0 221 2210.0 nan 20 68 68 220 268 480.0 nan nan nan GAATACGAATTCCCTTCCCATGAC 38 ATGTCTTGGGTCCGCAAGACTCCGGAGAAGAGGCTGGAGTTGGTCGCAGCC 38 ATTAATAGTGATGGTGGTAGCACC 38 TACTATCCAGACACCATGGAGAGACGATTCATCATCTCCAGAGACAATACCAAGAAGACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACAGCCTTGTATTAC 38
19 1331 0.00301289 GGCTACACATTTACTGACTATGAAATGCACTGGGTGAAGCAGACACCTGTGCATGGCCTGGAATGGATTGGAGCTATTGATCCTGAAACTGGTGGTACTGCCTACAATCAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCCGTCTATTACTGTACAAGAAGGGACCATGGTAACTACGGCTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-15*00(2688.6) IGHD2-8*00(61) IGHJ2*00(380) IGHG2C*00(64.2) 232 451 471 0 219 ST362C 2161.0 20 35 51 223 238 ST22C 61.0 30 68 68 239 277 380.0 nan nan nan GGCTACACATTTACTGACTATGAA 38
20 1297 0.00293592 GGCTACACATTTACTGACTATGAAATGCACTGGGTGAAGCAGACACCTGTGCATGGCCTGGAATGGATTGGAGCTATTGATCCTGAAACTGGTGGTACTGCCTACAATCAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCCGTCTATTACTGTACAAGACGCTACGGTAGTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-15*00(2688.3) IGHD1-1*00(45) IGHJ2*00(410) IGHG2C*00(64.1) 232 451 471 0 219 ST362C 2161.0 30 39 69 221 230 45.0 27 68 68 230 271 410.0 nan nan nan GGCTACACATTTACTGACTATGAA 38
21 1230 0.00278426 GGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAATGGTGGTGGTAGCACCTACTATCCAGACACTGTAAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACGGCCATGTATTACTGTGCAAGACATTATTACTACGGTAGTAGCTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-12*00(2457.4) IGHD1-1*00(95) IGHJ2*00(490) IGHM*00(64.9) 232 451 471 0 219 SG247ASA248GST253ASA254CSA260CST333CSC409ASA429G 1958.0 24 43 69 221 240 95.0 19 68 68 240 289 490.0 nan nan nan GGATTCACTTTCAGTAGCTATACC 38
22 1130 0.0025579 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATGGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1425.2) nan IGHJ2*00(500) IGHM*00(63.6) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 nan 18 68 68 221 271 500.0 nan nan nan GGCTACACATTCACTGATTATGCT 38 ATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTT 38 ATTAGTACTTACTCTGGTAATACA 38 AACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTAC 38
23 1124 0.00254432 GGATTCACTTTCAGTGACTACGGAATGGCGTGGGTTCGACAGGCTCCAGGGAAGGGGCCTGAGTGGGTAGCATTCATTAGTAATTTGGCATATAGTATCTACTATGCAGACACTGTGACGGGCCGATTCACCATCTCTAGAGAGAATGCCAAGAACACCCTGTACCTGGAAATGAGCAGTCTGAGGTCTGAGGACACAGCCATGTACTACTGTGCAAGGGATTACTACGGTAGTAGCTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-15*00(2590.3) IGHD1-1*00(55) IGHJ1*00(551) IGHM*00(64.8) 232 450 471 0 218 SA280GSG429AST438C 2093.0 26 37 69 220 231 55.0 15 73 73 231 289 SA45G 551.0 nan nan nan GGATTCACTTTCAGTGACTACGGA 38
24 1074 0.00243113 GGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGGATTGATCCTGAGAATGGTAATACTATATATGACCCGAAGTTCCAGGGCAAGGCCAGTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGAGGGGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV14-200(2340.9),IGHV14-400(2324.4) nan IGHJ3*00(450) IGHM*00(64.8) 232 451 471 0 219 SA277CSA304TSG319ASG325ASA327TSA332TSC338ASA345GSC362G 1929.0;232 449 471 0 217 ST237CSG250TSG325ASG331ASA332TSC338AST340CSC362GSA445G 1909.0 nan 23 68 68 223 268 450.0 nan nan nan GGCTTCAACATTAAAGACTACTAT 38
25 1024 0.00231795 GGATACACATTCACTAGCTATGTTATGCACTGGGTGAAGCAGAAGCCTGGGCAGGGCCTTGAGTGGATTGGATATATTAATCCTTACAATGATGGTACTAAGTACAATGAGAAGTTCAAAGGCAAGGCCACACTGACTTCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTACTGTGCAAGAGAGGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-83*00(1934.7) nan IGHJ3*00(450) IGHM*00(64.9) 182 401 421 0 219 SG197ASA198GSC202TST203GSA204TSC205TSA233CSG254TSG256TST260ASG266TSG267ASA268CSG270ASG273ASA275GSA276GST281ASC283GSG301ASG320TSC327ASC350GSA367CSA382GST390A 1436.0 nan 23 68 68 223 268 450.0 nan nan nan GGATACACATTCACTAGCTATGTT 38 ATGCACTGGGTGAAGCAGAAGCCTGGGCAGGGCCTTGAGTGGATTGGATAT 38 ATTAATCCTTACAATGATGGTACT 38 AAGTACAATGAGAAGTTCAAAGGCAAGGCCACACTGACTTCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTAC 38
26 1014 0.00229532 GGCTACACATTTACTGACTATGAAATGCACTGGGTGAAGCAGACACCTGTGCATGGCCTGGAATGGATTGGAGCTATTGATCCTGAAACTGGTGGTACTGCCTACAATCAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCCGTCTATTACTGTACAAGATGGTTACTACCTTTCGACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-15*00(2697.9) IGHD2-3*00(45) IGHJ4*00(510) IGHG2C*00(63.5) 232 452 471 0 220 ST362C 2171.0 25 34 51 220 229 45.0 23 74 74 235 286 510.0 nan nan nan GGCTACACATTTACTGACTATGAA 38
27 1001 0.00226589 GGCTACACATTTACTGACTATGAAATGCACTGGGTGAAGCAGACACCTGTGCATGGCCTGGAATGGATTGGAGCTATTGATCCTGAAACTGGTGGTACTGCCTACAATCAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCCGTCTATTACTGTACAAGACGGTTTCCTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-15*00(2687.8) IGHD5-700(25),IGHD5-800(25),IGHD6-2*00(25) IGHJ2*00(410) IGHG2C*00(64.1) 232 451 471 0 219 ST362C 2161.0 57 62 87 219 224 25.0;57 62 87 219 224 25.0;57 62 87 219 224 25.0
28 998 0.0022591 GGTTACTCATTCACTGGCTACTACATGCACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGACGTGTTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCATATTAACTGTAGACAAGTCATCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGAAATCTACTATGGTAACTCCGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-2600(2261.7),IGHV1-3400(2204.2) IGHD2-8*00(75) IGHJ3*00(451) IGHM*00(64.7) 232 449 471 0 217 SA234TSA238TSG240ASA248GSA259CSG304CSA305GSA307GSC362TSG366ASC381ASA432GSC446A 1793.0;232 449 471 0 217 SC234TSA238TSA248GST304CSA305GSA307GST310ASA329CSG331ASC362TSG366ASC381ASA432GSC446A 1764.0 17 32 51 217 232 75.0 20 68 68 232 280 ST22G
29 962 0.00217761 GGGTTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGAGATGGTAACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV7-3*00(2605) nan IGHJ1*00(481) IGHM*00(65) 232 460 481 0 228 SA234GSG282AST414CSG415AST457G 2135.0 nan 22 73 73 232 283 SA45G 481.0 nan nan nan GGGTTCACCTTCACTGATTACTAC 38 ATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTT 38 ATTAGAAACAAAGCTAATGGTTACACAACA 38 GAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTAC 38
30 957 0.00216629 GGATTCACTTTCAGTAACTACTGGATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAAATTAGATTGAAATCTAATAATTATGCAACACATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGAGCTGAAGACACTGGCATTTATTACTGTACCAGGAGCTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV6-3*00(2590.8) nan IGHJ3*00(430) IGHM*00(64.9) 232 453 476 0 221 SC304GSG322ASG423ASA438CSC450T 2065.0 nan 25 68 68 228 271 430.0 nan nan nan GGATTCACTTTCAGTAACTACTGG 38 ATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAA 38 ATTAGATTGAAATCTAATAATTATGCAACA 38 CATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGAGCTGAAGACACTGGCATTTATTAC 38
31 917 0.00207575 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATACGGTAGTAGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1426.3) IGHD1-1*00(50) IGHJ2*00(470) IGHM*00(64.9) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 32 42 69 220 230 50.0 21 68 68 230 277 470.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
32 912 0.00206443 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATACGGTAGTAGCTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1454.4) IGHD1-1*00(55) IGHJ1*00(431) IGHM*00(64.8) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 32 43 69 220 231 55.0 27 73 73 231 277 SA45G 431.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
33 894 0.00202368 GGATTCACTTTCAGTAACTACTGGATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAAATTAGATTGAAATCTAATAATTATGCAACACATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGAGCTGAAGACACTGGCATTTATTACTGTACCAGGGCGGGAAACTCGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV6-3*00(2591.9) nan IGHJ3*00(502) IGHM*00(64.7) 232 453 476 0 221 SC304GSG322ASG423ASA438CSC450T 2065.0 nan 12 68 68 230 286 SC16TSA17C 502.0 nan nan nan GGATTCACTTTCAGTAACTACTGG 38 ATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAA 38 ATTAGATTGAAATCTAATAATTATGCAACA 38 CATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGAGCTGAAGACACTGGCATTTATTAC 38
34 886 0.00200557 GGCTACACCTTCACTACCTATCCAATAGAGTGGATGAAGCAGAATCATGGGAAGAGCCTAGAGTGGATTGGAAATTTTCATCCTTACAATGATGATACTAAGTACAATGAAAAATTCAAGGGCAAGGCCAAATTGACTGTAGAAAAATCCTCTAGCACAGTCTACTTGGAGCTCAGCCGATTAACATCTGATGACTCTGCTGTTTATTACTGTGCAAGGCACCCCTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-47*00(2523.7) nan IGHJ3*00(370) IGHG2C*00(64.3) 232 452 471 0 220 ST255ASA282GSG345ASC362A 2084.0 nan 31 68 68 225 262 370.0 nan nan nan GGCTACACCTTCACTACCTATCCA 38 ATAGAGTGGATGAAGCAGAATCATGGGAAGAGCCTAGAGTGGATTGGAAAT 38 TTTCATCCTTACAATGATGATACT 38 AAGTACAATGAAAAATTCAAGGGCAAGGCCAAATTGACTGTAGAAAAATCCTCTAGCACAGTCTACTTGGAGCTCAGCCGATTAACATCTGATGACTCTGCTGTTTATTAC 38
35 885 0.00200331 GAATACGAATTCCCTTCCCATGACATGTCTTGGGTCCGCAAGACTCCGGAGAAGAGGCTGGAGTTGGTCGCAGCCATTAATAGTGATGGTGGTAGCACCTACTATCCAGACACCATGGAGAGACGATTCATCATCTCCAGAGACAATACCAAGAAGACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACAGCCTTGTATTACTGTGCAAGACATGGTAACTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-2*00(2757.5) IGHD2-300(25),IGHD2-700(25),IGHD2-8*00(25) IGHJ4*00(520) IGHM*00(64.8) 232 455 473 0 223 2230.0 3 8 51 223 228 25.0;3 8 51 223 228 25.0;26 31 51 223 228 25.0
36 879 0.00198973 GGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAATGGTGGTGGTAGCACCTACTATCCAGACACTGTAAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACGGCCATGTATTACTGTGCAAGACATTACTACGGTAGTAGCTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-12*00(2456.9) IGHD1-1*00(55) IGHJ1*00(551) IGHM*00(64.7) 232 451 471 0 219 SG247ASA248GST253ASA254CSA260CST333CSC409ASA429G 1958.0 26 37 69 220 231 55.0 15 73 73 231 289 SA45G 551.0 nan nan nan GGATTCACTTTCAGTAGCTATACC 38
37 855 0.0019354 GGCTACACCTTTACTAGCTACACGATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATTGGATACATTAATCCTAGCAGTGGTTATACTAATTACAATCAGAAGTTCAAGGACAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTGAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGAAAGGACTACGGTAGTAGCTCGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-4*00(2654.7) IGHD1-1*00(65) IGHJ3*00(441) IGHM*00(64.9) 232 451 471 0 219 SG333T 2161.0 29 42 69 223 236 65.0 21 68 68 236 283 SG23C 441.0 nan nan nan GGCTACACCTTTACTAGCTACACG 38
38 853 0.00193087 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATATGATTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1434.6) IGHD2-300(25),IGHD2-400(25) IGHJ2*00(490) IGHM*00(64.8) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 20 25 51 220 225 25.0;23 28 51 220 225 25.0 19 68 68 225 274
39 853 0.00193087 GGATACGCCTTCACTAATTACTTGATAGAGTGGGTAAAGCAGAGGCCTGGACAGGGCCTTGAGTGGATTGGAGTGATTAATCCTGGAAGTGGTGGTACTAACTACAATGAGAAGTTCAAGGGCAAGGCAACACTGACTGCAGACAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGATGACTCTGCGGTCTATTTCTGTGCAAGATGGGATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-54*00(2697.3) nan IGHJ4*00(540) IGHM*00(64.9) 232 452 471 0 220 SG423T 2171.0 nan 20 74 74 223 277 540.0 nan nan nan GGATACGCCTTCACTAATTACTTG 38 ATAGAGTGGGTAAAGCAGAGGCCTGGACAGGGCCTTGAGTGGATTGGAGTG 38 ATTAATCCTGGAAGTGGTGGTACT 38 AACTACAATGAGAAGTTCAAGGGCAAGGCAACACTGACTGCAGACAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGATGACTCTGCGGTCTATTTC 38
40 843 0.00190824 GGGTTCTCATTATCCAGATATAGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAATGATATGGGGTGGTGGAAGCACAGACTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGAAATGATTACGACTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-6-800(2359.6),IGHV2-600(2311.7) IGHD2-4*00(50) IGHJ3*00(470) IGHM*00(64.8) 232 447 470 0 215 SA244TSC249ASG253ASG259CST274CSG304ASA306GST317GSA328GST330C 1860.0;232 448 468 0 216 SA244TSC249ASG253AST302GSG304ASA313GSA317GSA328GSC329ASC411G 1870.0 23 33 51 217 227 50.0 21 68 68 227 274
41 825 0.00186749 GGGTTTTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTAATATGGGCTGGTGGAAGCACAAATTATAATTCGGCTCTCATGTCCAGACTGAGCATCAGCAAAGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGAGAGGGGGATCTACTATGGTTACGACATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-9*00(2580.5) IGHD2-700(95),IGHD2-400(81) IGHJ4*00(480) IGHM*00(64.8) 232 446 469 0 214 SG259CSG314CSA339G 2053.0 15 34 51 222 241 95.0;15 34 51 222 241 SA26G 81.0 26 74 74 241 289
42 769 0.00174073 GGCTTCAACATTAAAGACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATACTAAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGAAATGGTAACGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV14-3*00(2543.5) IGHD2-8*00(40) IGHJ3*00(400) IGHM*00(64.3) 232 451 471 0 219 SA247GSC338AST369ASA433G 2074.0 23 31 51 220 228 40.0 28 68 68 228 268 400.0 nan nan nan GGCTTCAACATTAAAGACACCTAT 38
43 766 0.00173394 GGCTACTCCTTCACCAGCTACTGGATGAACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGCATGATTCATCCTTCCGATAGTGAAACTAGGTTAAATCAGAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCCGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGAGGGGACTATAGGTACGGGGTGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-7400(2147.3),IGHV1-6100(2117.3) IGHD2-500(35),IGHD2-600(35),IGHD5-1*00(35) IGHJ4*00(420) IGHG2C*00(63.2) 232 449 471 0 217 SA238TSC259ASC282ASA303CSG305TST318CST327ASA332GSC333GSA335TSC336ASA342GSG353ASG402AST413C 1735.0;232 451 471 0 219 SA238TSG259AST261CSA294GST303CSA305TSC306GST310CSC312TST318CSC331ASA332GSC333GSA335TSC336ASA342GSG402AST413C 1668.0 6 13 51 223 230 35.0;6 13 51 223 230 35.0;1
44 751 0.00169998 GGCTACACCTTCACCAGCTACTATATGTACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAGATTAATCCTAGCAATGGTGGTACTAACTTCAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCATACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTACAAGAAGGAGGAATTACTACGGTAGTAGCTACGGAGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-53*00(2368.7) IGHD1-1*00(106) IGHJ3*00(450) IGHM*00(64.7) 232 451 471 0 219 SG254ASG255TSC259TSA304GST306GSA335TSC393ASG402AST441CSG445A 1900.0 26 50 69 226 250 ST47G 106.0 23 68 68 250 295 450.0 nan nan nan GGCTACACCTTCACCAGCTACTAT 38
45 690 0.0015619 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACTAACTGGTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2715.6) IGHD4-1*00(40) IGHJ3*00(410) IGHM*00(64.7) 232 451 471 0 219 2190.0 11 19 33 219 227 40.0 27 68 68 227 268 410.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38
46 683 0.00154606 GGGTTTTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTAATATGGGCTGGTGGAAGCACAAATTATAATTCGGCTCTCATGTCCAGACTGAGCATCAGCAAAGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGAGGGTACTACGGTAGTAGCTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-9*00(2580.7) IGHD1-1*00(45) IGHJ1*00(551) IGHM*00(64.7) 232 446 469 0 214 SG259CSG314CSA339G 2053.0 28 37 69 219 228 45.0 15 73 73 228 286 SA45G 551.0 nan nan nan GGGTTTTCATTAACCAGCTATGGT 38
47 682 0.00154379 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATGGGGGTACTACGGTAGTAGCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1437.5) IGHD1-1*00(70) IGHJ4*00(500) IGHM*00(64.9) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 28 42 69 225 239 70.0 24 74 74 239 289 500.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
48 679 0.001537 GGCTACACCTTCACTGACCATGCTATTCACTGGGTGAAGCAGAAGCCTGAACAGGGCCTGGAATGGATTGGATATATTTCTCCCGGAAATGGTGATATTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACTGCCTACATGCAGCTCAACAGCCTGACATCTGAGGATTCTGCAGTGTATTTCTGTAAAAGATGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-78*00(2202.3) nan IGHJ2*00(400) IGHM*00(64.8) 232 452 471 0 220 SA253GSA265GSG275ASA311CST315CSA316GSG319ASA325GSG326ASC329TST364CSA390TSC426TSC435GSG445ASC446A 1736.0 nan 28 68 68 222 262 400.0 nan nan nan GGCTACACCTTCACTGACCATGCT 38 ATTCACTGGGTGAAGCAGAAGCCTGAACAGGGCCTGGAATGGATTGGATAT 38 ATTTCTCCCGGAAATGGTGATATT 38 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACTGCCTACATGCAGCTCAACAGCCTGACATCTGAGGATTCTGCAGTGTATTTC 38
49 666 0.00150758 GGATTCACTTTCAGTAGCTTTGGAATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATACATTAGTAGTGGCAGTAGTACCATCTACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGATACTATGGTAATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-17*00(2478.7) IGHD2-800(50),IGHD2-700(45) IGHJ4*00(480) IGHM*00(64.9) 232 450 471 0 218 SG247ASA248GSA251TST300CSG379CSG414A 2006.0 19 29 51 219 229 50.0;19 28 51 219 228 45.0 26 74 74 229 277
50 615 0.00139213 GGATTCACTTTCAGTAGCTTTGGAATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATACATTAGTAGTGGCAGTAGTACCATCTACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGATACTATGGTAACTACGCCTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-17*00(2477.9) IGHD2-8*00(80) IGHJ3*00(430) IGHM*00(64.9) 232 450 471 0 218 SG247ASA248GSA251TST300CSG379CSG414A 2006.0 19 35 51 219 235 80.0 25 68 68 237 280 430.0 nan nan nan GGATTCACTTTCAGTAGCTTTGGA 38
51 609 0.00137855 GGCTACTCAATCACCAGTGATTATGCCTGGAACTGGATCCGGCAGTTTCCAGGAAACAAACTGGAGTGGATGGGCTACATAAGCTACAGTGGTAGCACTAGCTACAACCCATCTCTCAAAAGTCGAATCTCTATCACTCGAGACACATCCAAGAACCAGTTCTTCCTGCAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTACTGTGCAAGATTTCTCTATGATGGTTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV3-100(2235.6),IGHV3-600(2204.7) IGHD2-3*00(55) IGHJ2*00(490) IGHM*00(64.9) 229 449 468 0 220 SC237ASG248ASA254CSC259ASA270GST273GSA329GSC342TSC360TSA368GST369AST378CST387GSA397C 1794.0;229 455 470 0 226 SC237ASG248AST253GSA254CSA294GSG316ASA317GSA326CSA329GSA350GSC360TST369AST378CST390CSA397CSG448TSA449T 1767.0 17 28 51 223 234 55.0 19 68 68 234 283
52 598 0.00135365 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATTGGACGGTAGTAGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1428.1) IGHD1-1*00(50) IGHJ2*00(470) IGHM*00(64.8) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 32 42 69 223 233 50.0 21 68 68 233 280 470.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
53 586 0.00132649 GAATACGAATTCCCTTCCCATGACATGTCTTGGGTCCGCAAGACTCCGGAGAAGAGGCTGGAGTTGGTCGCAGCCATTAATAGTGATGGTGGTAGCACCTACTATCCAGACACCATGGAGAGACGATTCATCATCTCCAGAGACAATACCAAGAAGACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACAGCCTTGTATTACTGTGCAAGACATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-2*00(2757.3) nan IGHJ2*00(480) IGHM*00(64.9) 232 455 473 0 223 2230.0 nan 20 68 68 226 274 480.0 nan nan nan GAATACGAATTCCCTTCCCATGAC 38 ATGTCTTGGGTCCGCAAGACTCCGGAGAAGAGGCTGGAGTTGGTCGCAGCC 38 ATTAATAGTGATGGTGGTAGCACC 38 TACTATCCAGACACCATGGAGAGACGATTCATCATCTCCAGAGACAATACCAAGAAGACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACAGCCTTGTATTAC 38
54 504 0.00114087 GGATTCACCTTCAATACCTACGCCATGAACTGGGTCCGCCAGGCTCCAGGAAAGGGTTTGGAATGGGTTGCTCGCATAAGAAGTAAAAGTAATAATTATGCAACATATTATGCCGATTCAGTGAAAGACAGGTTCACCATCTCCAGAGATGATTCACAAAGCATGCTCTATCTGCAAATGAACAACTTGAAAACTGAGGACACAGCCATGTATTACTGTGTAGCTAACTGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV10-1*00(2648) IGHD4-1*00(50) IGHJ2*00(400) IGHM*00(64.7) 232 453 477 0 221 SG239CSA363GSG388C 2123.0 9 19 33 221 231 50.0 28 68 68 231 271 400.0 nan nan nan GGATTCACCTTCAATACCTACGCC 38
55 494 0.00111823 GAATACGAATTCCCTTCCCATGACATGTCTTGGGTCCGCAAGACTCCGGAGAAGAGGCTGGAGTTGGTCGCAGCCATTAATAGTGATGGTGGTAGCACCTACTATCCAGACACCATGGAGAGACGATTCATCATCTCCAGAGACAATACCAAGAAGACCCTGTACCTGCAAATGAGCAGTCTGAGGTCTGAGGACACAGCCTTGTATTACTGTGCAAGACATGCCCGATATTACTACGGTAGTAGCCTCTGGGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-2*00(2756.6) IGHD1-1*00(90) IGHJ4*00(460) IGHM*00(64.9) 232 455 473 0 223 2230.0 25 43 69 228 246 90.0 28 74 74 252 298 460.0 nan nan nan GAATACGAATTCCCTTCCCATGAC 38
56 492 0.0011137 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACATGATTACGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2714.7) IGHD2-4*00(40) IGHJ2*00(400) IGHM*00(64.9) 232 451 471 0 219 2190.0 23 31 51 220 228 40.0 28 68 68 228 268 400.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38
57 491 0.00111144 GGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCGGAGAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTACCTATGGTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2482.9) IGHD2-700(30),IGHD2-800(30) IGHJ2*00(410) IGHM*00(64.9) 232 445 471 0 213 SG253ASG254CSA279GSC282GSG354C 1985.0 21 27 51 215 221 30.0;21 27 51 215 221 30.0 27 68 68 221 262
58 490 0.00110918 GGATTCACCTTCAATACCTACGCCATGAACTGGGTCCGCCAGGCTCCAGGAAAGGGTTTGGAATGGGTTGCTCGCATAAGAAGTAAAAGTAATAATTATGCAACATATTATGCCGATTCAGTGAAAGACAGGTTCACCATCTCCAGAGATGATTCACAAAGCATGCTCTATCTGCAAATGAACAACTTGAAAACTGAGGACACAGCCATGTATTACTGTGTGAGACACGAACTACGTTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV10-1*00(2688.5) IGHD2-500(40),IGHD2-600(40),IGHD2-8*00(40) IGHJ1*00(491) IGHM*00(64.8) 232 457 477 0 225 SG239CSA363GSG388C 2163.0 28 36 51 229 237 40.0;28 36 51 229 237 40.0;28 36 51 229 237 40.0
59 486 0.00110012 GGATTCACTTTCAGTAGCTTTGGAATGCACTGGGTTCGTCAGGCTCCAGAGAAGGGGCTGGAGTGGGTCGCATACATTAGTAGTGGCAGTAGTACCATCTACTATGCAGACACAGTGAAGGGCCGATTCACCATCTCCAGAGACAATCCCAAGAACACCCTGTTCCTGCAAATGACCAGTCTAAGGTCTGAGGACACGGCCATGTATTACTGTGCAAGACTGGGACTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-17*00(2477.6) IGHD4-1*00(40) IGHJ2*00(420) IGHM*00(64.8) 232 450 471 0 218 SG247ASA248GSA251TST300CSG379CSG414A 2006.0 14 22 33 218 226 40.0 26 68 68 226 268 420.0 nan nan nan GGATTCACTTTCAGTAGCTTTGGA 38
60 479 0.00108428 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGAGGGTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2714.6) nan IGHJ2*00(430) IGHM*00(64.8) 232 451 471 0 219 2190.0 nan 25 68 68 222 265 430.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38 ATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACC 38 ATTAGTAGTGGTGGTAGTTACACC 38 TACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTAC 38
61 475 0.00107522 GGGTTCTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGTAGTGATATGGAGTGATGGAAGCACAACCTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTCCAAACTGATGACACAGCCATGTACTACTGTGCCAGACAGGCCTACTATGGTAACTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-6*00(2659.8) IGHD2-500(55),IGHD2-600(55) IGHJ1*00(512) IGHM*00(64.9) 232 448 468 0 216 2160.0 14 25 51 217 228 55.0;14 25 51 217 228 55.0 16 73 73 229 286 SG19ASA45G
62 468 0.00105938 GGTTACTCATTCACTGACTACAACATGTACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGATATATTGATCCTTACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTTGACAAGTCCTCCAGCACAGCCTTCATGCATCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGATCAGGGGGCTACAGTAGCCTACGGGGTGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-1900(2273.8),IGHV1-1800(2252.7),IGHV1-26*00(2247.5) IGHD3-100(53),IGHD3-200(53) IGHJ4*00(470) IGHG2C*00(62.8) 232 453 471 0 221 SA234TSA238TST253AST255CSA259TSG304TST305ASA310GSC321TSA395TSG400CSG402T 1862.0;232 453 471 0 221 SA234TSA238TSG259TSG304TSA310GSA316TST332GSA372TSA395TSG400CSG402TSC406ASG407ASA427T 1804.0;232 453 471 0 221 SA234TSA238TSG240AST253ASA259TSG304TSA310GSA316TSA372TSA395TSG400CSG402TSC406ASG407A 1804.0 27 40 51 224 238 I34A 53.0;26
63 459 0.001039 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATCGGGGGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1441.1) nan IGHJ4*00(460) IGHM*00(64.9) 232 453 471 0 221 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1253.0 nan 28 74 74 225 271 460.0 nan nan nan GGCTACACATTCACTGATTATGCT 38 ATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTT 38 ATTAGTACTTACTCTGGTAATACA 38 AACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTAC 38
64 442 0.00100052 GGCTACTCAATCACCAGTGATTATGCCTGGAACTGGATCCGGCAGTTTCCAGGAAACAAACTGGAGTGGATGGGCTACATAAGCTACAGTGGTAGCACTAGCTACAACCCATCTCTCAAAAGTCGAATCTCTATCACTCGAGACACATCCAAGAACCAGTTCTTCCTGCAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTACTGTGCAAGATGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV3-100(2235.5),IGHV3-600(2190.9) nan IGHJ3*00(460) IGHM*00(65) 229 449 468 0 220 SC237ASG248ASA254CSC259ASA270GST273GSA329GSC342TSC360TSA368GST369AST378CST387GSA397C 1794.0;229 448 470 0 219 SC237ASG248AST253GSA254CSA294GSG316ASA317GSA326CSA329GSA350GSC360TST369AST378CST390CSA397C 1755.0 nan 22 68 68 219 265 460.0 nan nan nan GGCTACTCAATCACCAGTGATTATGCC 38
65 434 0.000982414 GGGTTCTCATTAACCGGCTATGGTGTAAACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAATGATATGGGGTGATGGAAGCACAGACTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCAGGTACTACTGTGCCAGAGATGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-600(2426.3),IGHV2-6-800(2369.6) nan IGHJ3*00(450) IGHM*00(64.7) 232 448 468 0 216 SA247GSC259AST302GSG304ASA313GSA328GSC329ASC411GST431G 1899.0;232 451 470 0 219 SA247GSG259AST274CSG304ASA306GST317ASA328GST330CST431GST447A 1900.0 nan 23 68 68 220 265 450.0 nan nan nan GGGTTCTCATTAACCGGCTATGGT 38
66 430 0.000973359 GGTTTCTCATTAACTAGCTATGGTGTACACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTGATATGGAGAGGTGGAAGCACAGACTACAATGCAGCTTTCATGTCCAGACTGAGCATCACCAAGGACAACTCCAAGAGCCAAGTTTTCTTTAAAATGAACAGTCTGCAAGCTGATGACACTGCCATATACTACTGTGCCAAATATGGTAACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-5*00(2681.5) nan IGHJ4*00(510) IGHM*00(64.8) 232 451 470 0 219 SA448T 2161.0 nan 23 74 74 223 274 510.0 nan nan nan GGTTTCTCATTAACTAGCTATGGT 38 GTACACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTG 38 ATATGGAGAGGTGGAAGCACA 38 GACTACAATGCAGCTTTCATGTCCAGACTGAGCATCACCAAGGACAACTCCAAGAGCCAAGTTTTCTTTAAAATGAACAGTCTGCAAGCTGATGACACTGCCATATACTAC 38
67 425 0.000962041 GGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCGGAGAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTACAAGAGATGGTTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2514.7) IGHD2-3*00(30) IGHJ2*00(370) IGHM*00(64.9) 232 451 471 0 219 SG253ASG254CSA279GSC282GSG354CSG445A 2016.0 22 28 51 219 225 30.0 31 68 68 225 262 370.0 nan nan nan GGATTCACTTTCAGTAGCTATACC 38
68 422 0.00095525 GGCTTCAACATTAAAGACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATACTAAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGGGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV14-3*00(2533.6) nan IGHJ2*00(420) IGHM*00(65) 232 450 471 0 218 SA247GSC338AST369ASA433G 2064.0 nan 26 68 68 220 262 420.0 nan nan nan GGCTTCAACATTAAAGACACCTAT 38 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGG 38 ATTGATCCTGCGAATGGTAATACT 38 AAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 38
69 420 0.000950723 GGGTTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGAGATGGGCTAAGGGCCCTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV7-3*00(2605.3) IGHD3-1*00(30) IGHJ3*00(420) IGHG2C*00(56.6) 232 460 481 0 228 SA234GSG282AST414CSG415AST457G 2135.0 27 33 51 228 234 30.0 26 68 68 241 283 420.0 nan nan nan GGGTTCACCTTCACTGATTACTAC 38
70 419 0.000948459 GGCTACACCTTCACCAGCTACTATATGTACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGGGGGATTAATCCTAGCAATGGTGGTACTAACTTCAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTACAAGTAACTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-53*00(2330.1) nan IGHJ3*00(470) IGHM*00(64.8) 232 450 471 0 218 SG254ASG255TSC259TSA303GSA304GSA305GST306GSA335TSG402AST441CSG445A 1861.0 nan 21 68 68 221 268 470.0 nan nan nan GGCTACACCTTCACCAGCTACTAT 38 ATGTACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGGGGG 38 ATTAATCCTAGCAATGGTGGTACT 38 AACTTCAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 38
71 419 0.000948459 GGATTCACTTTTAGTGACGCCTGGATGGACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAAATTAGAAGCAAAGCTAATAATCATGCAACATACTATGCTGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAGCTTAAGAGCTGAAGACACTGGCATTTATTACTGTACCAACTATAGGTACGACTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV6-6*00(2728.5) IGHD2-700(37),IGHD2-600(35),IGHD5-1*00(35) IGHJ3*00(470) IGHG2C*00(63.6) 232 455 477 0 223 SA314G 2201.0 20 33 51 223 236 SG25AST27G 37.0;6 13 51 223 230 35.0;1 8 30 227 234 35.0
72 418 0.000946196 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACTAACTGGGGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2713.3) IGHD4-1*00(45) IGHJ3*00(400) IGHM*00(64.8) 232 451 471 0 219 2190.0 11 20 33 219 228 45.0 28 68 68 228 268 400.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38
73 415 0.000939405 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACACTATGGTAACTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2714.7) IGHD2-8*00(55) IGHJ2*00(490) IGHM*00(64.8) 232 451 471 0 219 2190.0 20 31 51 220 231 55.0 19 68 68 231 280 490.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38
74 405 0.000916769 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACAATGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATACGGTAGTAGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1492.1) IGHD1-1*00(50) IGHJ2*00(470) IGHM*00(64.8) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1301.0 32 42 69 220 230 50.0 21 68 68 230 277 470.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
75 401 0.000907714 GGCTACACCTTCACTACCTATCCAATAGAGTGGATGAAGCAGAATCATGGGAAGAGCCTAGAGTGGATTGGAAATTTTCATCCTTACAATGATGATACTAAGTACAATGAAAAATTCAAGGGCAAGGCCAAATTGACTGTAGAAAAATCCTCTAGCACAGTCTACTTGGAGCTCAGCCGATTAACATCTGATGACTCTGCTGTTTATTACTGTGCAAGGTATGGTAACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-47*00(2512.5) IGHD2-800(35),IGHD2-700(30) IGHJ4*00(510) IGHM*00(64.9) 232 451 471 0 219 ST255ASA282GSG345ASC362A 2074.0 22 29 51 219 226 35.0;22 28 51 219 225 30.0 23 74 74 226 277
76 401 0.000907714 GGCTACACCTTCACCAGCTCCTGGATGCACTGGGCGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAGATTCATCCTAATAGTGGTAATACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACGTGGATCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGCGGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-64*00(2215.2) nan IGHJ2*00(470) IGHM*00(64.4) 232 450 471 0 218 ST240CSA251CST266CSA304GST305ASG326ASA352GSA377CSA397GSC400GSA402T 1861.0 nan 21 68 68 221 268 470.0 nan nan nan GGCTACACCTTCACCAGCTCCTGG 38 ATGCACTGGGCGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAG 38 ATTCATCCTAATAGTGGTAATACT 38 AACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACGTGGATCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 38
77 393 0.000889605 GGCTACACCTTTACCAGCTACTGGATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATTGGCGCTATTTATCCTGGAAATAGTGATACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCACCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTACTGTACAAGAGAGGTACGAAACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-5*00(2567.2) IGHD5-1*00(30) IGHJ2*00(360) IGHG1*00(35.5) 232 451 471 0 219 SA240CSA300TSG303CSG382A 2074.0 2 8 30 220 226 30.0 32 68 68 229 265 360.0 nan nan nan GGCTACACCTTTACCAGCTACTGG 38
78 393 0.000889605 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACAATGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATCGAGGGGTAGTAGCTATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1480.9) IGHD1-1*00(45) IGHJ4*00(550) IGHM*00(64.9) 232 453 471 0 221 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1311.0 34 43 69 225 234 45.0 19 74 74 234 289 550.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
79 390 0.000882814 GGGTTTTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTAATATGGGCTGGTGGAAGCACAAATTATAATTCGGCTCTCATGTCCAGACTGAGCATCAGCAAAGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGAGATTACTACGGTAGTAGCTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-9*00(2579.7) IGHD1-1*00(55) IGHJ1*00(551) IGHM*00(65.2) 232 446 469 0 214 SG259CSG314CSA339G 2053.0 26 37 69 217 228 55.0 15 73 73 228 286 SA45G 551.0 nan nan nan GGGTTTTCATTAACCAGCTATGGT 38
80 385 0.000871496 GGCTTCAACATTAAAGACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATACTAAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTCGGATCTATGATGGTTACTACGGCTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV14-3*00(2512.3) IGHD2-3*00(100) IGHJ2*00(380) IGHM*00(65) 232 448 471 0 216 SA247GSC338AST369ASA433G 2044.0 15 35 51 218 238 100.0 30 68 68 239 277 380.0 nan nan nan GGCTTCAACATTAAAGACACCTAT 38
81 378 0.000855651 GGCTACACCTTTACTAGCTACTGGATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATTGGATACATTAATCCTAGCACTGGTTATACTGAGTACAATCAGAAGTTCAAGGACAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTGAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGATACTGGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-700(2577.5),IGHV1-400(2535.2) IGHD4-1*00(25) IGHJ2*00(460) IGHM*00(64.9) 232 452 471 0 220 SG320CSA331GSG402ASA419C 2084.0;232 452 471 0 220 SA253TSC254GSG320CSA331G 2084.0 14 19 33 220 225 25.0 22 68 68 225 271
82 375 0.00084886 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACAATGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATATGATTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1466.2) nan IGHJ4*00(502) IGHM*00(64.9) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1301.0 nan 18 74 74 218 274 ST22GSC24T 502.0 nan nan nan GGCTACACATTCACTGATTATGCT 38 ATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTT 38 ATTAGTACTTACAATGGTAATACA 38 AACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTAC 38
83 371 0.000839805 GGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTAGTGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACAGTATGGTAACTACTATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-6*00(2714.2) IGHD2-8*00(60) IGHJ2*00(480) IGHM*00(64.7) 232 451 471 0 219 2190.0 22 34 51 222 234 60.0 20 68 68 241 289 480.0 nan nan nan GGATTCACTTTCAGTAGCTATGGC 38
84 369 0.000835278 GGATTCACTTTCAGTGACTATTACATGTATTGGGTTCGCCAGACTCCGGAAAAGAGGCTGGAGTGGGTCGCAACCATTAGTGATGGTGGTAGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACAACCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGATATAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-400(2436.5),IGHV5-600(2408.6) nan IGHJ4*00(520) IGHM*00(64.9) 232 452 471 0 220 SA247GSG248ASG253TSC254ASC260ASA344GSA348GSC354GSC409ASA410G 1910.0;232 452 471 0 220 SA247GSG248ASG253TSG254ASC260ASA279GSC282ASA313GSG314ASC389A 1910.0 nan 22 74 74 225 277 520.0 nan nan nan GGATTCACTTTCAGTGACTATTAC 38
85 365 0.000826224 GGATACATCTTCACCAGCTACTGGATTCACTGGGTAAAACAGAGGTCTGGACAGGGCCTTGAGTGGATTGCAAGGATTTATCCTGGAACTGGTAGTACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGAAATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGAGGGAACTATGACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-76*00(2136.9) nan IGHJ4*00(521) IGHM*00(65.2) 232 451 471 0 219 SC234ASC239TST240CST246CSG247ASA248GSA254GST255GSA258TSA259CSG267ASG270ASC277TSA288CSG320CSA326GSA375CSC416A 1668.0 nan 19 74 74 225 280 ST22G 521.0 nan nan nan GGATACATCTTCACCAGCTACTGG 38 ATTCACTGGGTAAAACAGAGGTCTGGACAGGGCCTTGAGTGGATTGCAAGG 38 ATTTATCCTGGAACTGGTAGTACT 38 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGAAATCTGAGGACTCTGCTGTCTATTTC 38
86 363 0.000821696 GGCTACACCTTCACAAGCTATGATATAAACTGGGTGAGGCAGAGGCCTGAACAGGGACTTGAGTGGATTGGATGGATTTTTCCTGGAGATGGTAGTACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGGCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGAACTATGATTACTGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-85*00(2197.2) IGHD2-4*00(40) IGHJ4*00(470) IGHM*00(65) 232 454 471 0 222 SC252TSA269GSG281ASA311TSA316GST364CSG370AST371CSC377ASG393CSG400CSC406ASA407GSC411GSG432TST451A 1756.0 23 31 51 222 230 40.0 27 74 74 230 277 470.0 nan nan nan GGCTACACCTTCACAAGCTATGAT 38
87 362 0.000819433 GGCTACACCTTCACCAGCTACTGGATTAACTGGATAAAACAGAGGCCTGGACAGGGCCTTGAGTGGATAGGACGTATTGCTCCTGGAAGTGGTAGTACTTACTACAATGAAATGTTCAAGGGCAAGGCAACACTGACTGTAGACACATCCTCCAGCACAGCCTACATTCAGCTCAGCAGCCTGTCATCTGAGGACTCTGCTGTCTATTTCTGTGCGACTATGATTACGACTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-5500(1858.2),IGHV1-7700(1857.9) IGHD2-4*00(70) IGHJ2*00(410) IGHM*00(65.1) 232 447 471 0 215 SA258TSC260ASG265ASG267ASG270ASA285GST300ASG304CSA305GST310GSA311CST318ASA331TSG342ASA344TSA352GSC360ASG399TSA415TSG432TSA440T 1541.0;232 447 471 0 215 ST246CSG247ASA248GSA254GST255GSA258TSG265ASG267ASG270AST300ASA304CSA305GSG306TSG311CSG342ASA344TSC360ASC371TSA377CSG399TSA415TSA432T 1512.0 20 34 51 216 230 70.0 27 68 68 230 271
88 353 0.00079906 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTATGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATACTATGGTTACGACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1471.9) IGHD2-7*00(60) IGHJ4*00(510) IGHM*00(65) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1272.0 20 32 51 220 232 60.0 23 74 74 232 283 510.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
89 351 0.000794533 GGATTCACTTTCAGTAGCTATACCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAATGGTGGTGGTAGCACCTACTATCCAGACACTGTAAAGGGCCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACGGCCATGTATTACTGTACCTACGGCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV5-12*00(2397.4) IGHD5-100(35),IGHD5-200(35),IGHD5-3*00(35) IGHJ4*00(500) IGHM*00(64.8) 232 445 471 0 213 SG247ASA248GST253ASA254CSA260CST333CSC409ASA429G 1898.0 14 21 30 213 220 35.0;14 21 30 213 220 35.0;14 21 30 213 220 35.0
90 350 0.000792269 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGATTGAGGGGTTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1461.7) nan IGHJ2*00(370) IGHM*00(65) 232 452 471 0 220 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1243.0 nan 31 68 68 228 265 370.0 nan nan nan GGCTACACATTCACTGATTATGCT 38 ATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTT 38 ATTAGTACTTACTCTGGTAATACA 38 AACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTAC 38
91 346 0.000783215 GGGTTCTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGTAGTGATATGGAGTGATGGAAGCACAACCTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTCCAAACTGATGACACAGCCATGTACTACTGTGCCAGACAAATCTATGATGGCTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-6*00(2660) IGHD2-3*00(50) IGHJ1*00(511) IGHM*00(64.9) 232 448 468 0 216 2160.0 16 26 51 219 229 50.0 19 73 73 229 283 SA45G 511.0 nan nan nan GGGTTCTCATTAACCAGCTATGGT 38
92 344 0.000778688 GGGTTCTCATTAACCGGCTATGGTGTAAACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAATGATATGGGGTGATGGAAGCACAGACTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCAGGTACTACTGTGCCAGACCAGCCTACTATGGTAACTACGACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-600(2426.1),IGHV2-6-800(2358.3) IGHD2-800(85),IGHD2-500(81),IGHD2-6*00(81) IGHJ4*00(510) IGHG2C*00(64) 232 448 468 0 216 SA247GSC259AST302GSG304ASA313GSA328GSC329ASC411GST431G 1899.0;232 447 470 0 215 SA247GSG259AST274CSG304ASA306GST317ASA328GST330CST431G 1889.0 18 35 51 221 238 85.0;16 35 51 219 238 SA25G 81.0;16
93 342 0.00077416 GGGTTTTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTAATATGGGCTGGTGGAAGCACAAATTATAATTCGGCTCTCATGTCCAGACTGAGCATCAGCAAAGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGGTCCTATTACTACGGTAGTAGCTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV2-9*00(2581.1) IGHD1-1*00(85) IGHJ2*00(440) IGHM*00(64.7) 232 446 469 0 214 SG259CSG314CSA339G 2053.0 25 42 69 219 236 85.0 24 68 68 236 280 440.0 nan nan nan GGGTTTTCATTAACCAGCTATGGT 38
94 341 0.000771897 GGCTACACCTTTACTAGCTACTGGATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATTGGATACATTAATCCTAGCACTGGTTATACTGAGTACAATCAGAAGTTCAAGGACAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTGAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGGCCCGGATGGTTACTACACTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-700(2562),IGHV1-400(2533.4) IGHD2-3*00(60) IGHJ1*00(501) IGHM*00(64.9) 232 450 471 0 218 SG320CSA331GSG402ASA419C 2064.0;232 450 471 0 218 SA253TSC254GSG320CSA331G 2064.0 22 34 51 223 235 60.0 20 73 73 236 289 SA45G
95 337 0.000762842 GGCTACACATTCACTGATTATGCTATGCACTGGGTGAAGCAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTCTGGTAATACAAACTACAACCAGAAGTTTAAGGGCAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGATTGACATCTGAGGATTCTGCCATCTATTACTGTGCAAGACAGCTCGGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-19*00(1387.1) IGHD3-1*00(40) IGHJ2*00(470) IGHM*00(64.6) 232 451 471 0 219 SA234CSC249TSC252TST253GSA254CSA259CSC276TSG281CSC288TST291ASA311GSC313ASA319TSA320CSC321TSG325ASG326AST330ASG332ASC348TST364AST372ASG378ASC396TSG402ASC405TSA406GSA407CSC411ASC412TSC426TSA432CSG433A 1233.0 21 29 51 219 227 40.0 21 68 68 227 274 470.0 nan nan nan GGCTACACATTCACTGATTATGCT 38
96 333 0.000753788 GGCTACTCCTTCACCAGCTACTGGATGAACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGCATGATTCATCCTTCCGATAGTGAAACTAGGTTAAATCAGAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCCGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGAACTGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-7400(2147),IGHV1-6100(2089.9) IGHD4-1*00(25) IGHJ3*00(450) IGHM*00(64.7) 232 449 471 0 217 SA238TSC259ASC282ASA303CSG305TST318CST327ASA332GSC333GSA335TSC336ASA342GSG353ASG402AST413C 1735.0;232 454 471 0 222 SA238TSG259AST261CSA294GST303CSA305TSC306GST310CSC312TST318CSC331ASA332GSC333GSA335TSC336ASA342GSG402AST413CST451A 1669.0 13 18 33 218 223 25.0 23 68 68 223 268
97 325 0.000735679 GGCTTCAACATTAAAGACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATACTAAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTGTACCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV14-3*00(2514.2) nan IGHJ3*00(480) IGHM*00(64.5) 232 448 471 0 216 SA247GSC338AST369ASA433G 2044.0 nan 20 68 68 220 268 480.0 nan nan nan GGCTTCAACATTAAAGACACCTAT 38 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGG 38 ATTGATCCTGCGAATGGTAATACT 38 AAATATGACCCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 38
98 325 0.000735679 GGCTACACCTTTACTAGCTACTGGATGCAGTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATTGGGGCTATTTATCCTGGAGATGGTGATACTAGGTACACTCAGAAGTTCAAGGGCAAGGCCACATTGACTGCAGATAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCTTGGCATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATCGGCCTATGGTAACTACTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV1-400(1986.3),IGHV1-700(1966.4) IGHD2-8*00(65) IGHJ3*00(430) IGHM*00(64.9) 232 453 471 0 221 SA253TSC254GSC261GSA303GST304GSA305CSC306TSA310TSA316GSC318ASA319GSG320AST325GSA332GSA338CSA353GSC375TSG405CSC412TSA415GSA432G 1601.0;232 453 471 0 221 SC261GSA303GST304GSA305CSC306TSA310TSA316GSC318ASA319GSG320AST325GSA332GSA338CSA353GSC375TSG402ASG405CSC412TSA415GSA419CSA432G 1601.0 21 34 51 224 237 65.0 25 68 68 237 280
99 325 0.000735679 GGGTTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGAAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAACACCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGATCCCCCTACGGCTACTGGTACTTCGATGTCTGGGGCGCAGGGACCACGGTCACCGTCTCCTCAG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG IGHV7-3*00(2614.3) IGHD5-100(30),IGHD5-200(30),IGHD5-3*00(30) IGHJ1*00(511) IGHM*00(64.7) 232 458 481 0 226 SA234GSG282AST414CSG415A 2144.0 15 21 30 229 235 30.0;15 21 30 229 235 30.0;15 21 30 229 235 30.0

Now, since we have multiple files ist easier to process them all together instead of running the same command multiple times. One of the ways to achieve it is to use GNU Parallel:

#!/usr/bin/env bash

mkdir -p results/

ls raw/*_1* | \
    parallel -j 4 \
    'mixcr analyze generic-amplicon -f \
    --species mmu \
    --rna \
    --rigid-left-alignment-boundary \
    --rigid-right-alignment-boundary \
    --tagPattern "^N{"4"}ccctcctttaattccc{"21"}(R1:*)\^N{"4"}gaggagagagagagagN{"26"}(R2:*)" \
    --assemble-clonotypes-by {CDR1Begin:FR4End} \
    {} \
    {=s:R1:R2:=} \
    {=s:.*/:results/:;s:_R.*::=}'

Under the hood

Under the hood, the command from above actually executes the following pipeline of MiXCR actions:

align

Performs:

  • alignment of raw sequencing reads against reference database of V-, D-, J- and C- gene segments
  • pattern matching of tag pattern sequence and extraction of barcodes
mixcr align \
    -p generic-amplicon \
    --species mmu \
    --tag-pattern '^(R1:*)\^(UMI:N{12})' \
    --report result/M1_4T1_replica1_Blood.align.report.txt \
    --json-report result/M1_4T1_replica1_Blood.align.report.json \
    -OvParameters.geneFeatureToAlign="VTranscriptWithout5UTRWithP" \
    -OvParameters.parameters.floatingLeftBound=false \
    -OjParameters.parameters.floatingRightBound=false \
    -OcParameters.parameters.floatingRightBound=false \
    raw/M1_4T1_replica1_Blood_R1.fastq.gz \
    raw/M1_4T1_replica1_Blood_R2.fastq.gz \
    results/M1_4T1_replica1_Blood.vdjca

Options --report and --json-report are specified here explicitly.

This step utilizes all available CPUs and scales perfectly. When there are a lot of CPUs, the only limiting factor is the speed of disk I/O. To limit the number of used CPUs one can pass --threads N option.

assemble

Assembles clonotypes and applies several layers of errors correction:

  • assembly consensus CDR3 sequence
  • quality-awared correction for sequencing errors
  • clustering to correct for PCR errors
mixcr assemble \
    --report results/M1_4T1_replica1_Blood.assemble.report.txt \
    --json-report results/P15-T0-TIGIT.assemble.report..json \
    -OassemblingFeatures={CDR1Begin:FR4End} \
    results/M1_4T1_replica1_Blood.vdjca \
    results/M1_4T1_replica1_Blood.clns

Options --report and --json-report are specified here explicitly so that the report files will be appended with assembly report.

exportClones

Finally, to export clonotype tables in tabular form exportClones is used:

mixcr exportClones \
     --chains IGH \
     results/M1_4T1_replica1_Blood.clns \
     results/M1_4T1_replica1_Blood.clones.tsv

Quality control

Now when the upstream analysis is finished we can move on to quality control. First lets look at the alignment report plot.

mixcr exportQc align results/*.clns figs/alignQc.pdf

alignQc.svg

We see that all samples have a very high score of successfully aligned reads. No significant issues present.

Next, lets look at the chain usage distribution.

mixcr exportQc chainUsage results/*.clns figs/chainUsage.pdf

chainUsage.svg

We don't see any contamination from other Ig chains. As expected, all samples consist only of IGH chains.

Downstream analysis

There are two types of basic downstream analysis: individual and overlap. Individual computes CDR3 metrics, diversity and gene usage metrics for each dataset. Overlap computes statistical metrics of repertoire overlap. In both cases MiXCR applies appropriate sample normalization.

To run postanalysis routines we need to prepare a metadata file in a .tsv or .csv form. Metadata must contain a sample column which will be used to match metadata with cloneset files. Bellow you can find a metadata table for our samples.

Metadata
sample mice_id condition tissue replica
M1_4T1_Blood_S2 M1 4T1 Blood 1
M1_4T1_Blood_S6 M1 4T1 Blood 2
M1_4T1_BM_S4 M1 4T1 BM 1
M1_4T1_BM_S8 M1 4T1 BM 2
M1_4T1_DLN_S3 M1 4T1 DLN 1
M1_4T1_DLN_S7 M1 4T1 DLN 2
M1_4T1_Tumor_S5 M1 4T1 Tumor 1
M1_4T1_Tumor_S1 M1 4T1 Tumor 2
M2_4T1_Blood_S2 M2 4T1 Blood 1
M2_4T1_Blood_S6 M2 4T1 Blood 2
M2_4T1_BM_S4 M2 4T1 BM 1
M2_4T1_BM_S8 M2 4T1 BM 2
M2_4T1_DLN_S3 M2 4T1 DLN 1
M2_4T1_DLN_S7 M2 4T1 DLN 2
M2_4T1_Tumor_S1 M2 4T1 Tumor 1
M2_4T1_Tumor_S5 M2 4T1 Tumor 2
M3_4T1_Blood_S10 M3 4T1 Blood 1
M3_4T1_Blood_S9 M3 4T1 Blood 2
M3_4T1_BM_S7 M3 4T1 BM 1
M3_4T1_BM_S8 M3 4T1 BM 2
M3_4T1_DLN_S11 M3 4T1 DLN 1
M3_4T1_DLN_S12 M3 4T1 DLN 2
M3_4T1_Tumor_S13 M3 4T1 Tumor 1
M3_4T1_Tumor_S14 M3 4T1 Tumor 2
M4_4T1_Blood_S2 M4 4T1 Blood 1
M4_4T1_Blood_S7 M4 4T1 Blood 2
M4_4T1_BM_S10 M4 4T1 BM 1
M4_4T1_BM_S5 M4 4T1 BM 2
M4_4T1_DLN_S4 M4 4T1 DLN 1
M4_4T1_DLN_S9 M4 4T1 DLN 2
M4_4T1_Tumor_S1 M4 4T1 Tumor 1
M4_4T1_Tumor_S6 M4 4T1 Tumor 2
N1_control_Blood_S5 N1 control Blood 1
N1_control_Blood_S6 N1 control Blood 2
N1_control_BM_S1 N1 control BM 1
N1_control_BM_S2 N1 control BM 2
N1_control_LN_S3 N1 control LN 1
N1_control_LN_S4 N1 control LN 2
N2_control_Blood_S5 N2 control Blood 1
N2_control_Blood_S6 N2 control Blood 2
N2_control_BM_S1 N2 control BM 1
N2_control_BM_S2 N2 control BM 2
N2_control_LN_S3 N2 control LN 1
N2_control_LN_S4 N2 control LN 2

Individual postanalysis

To compute a set of individual metrics we run the following command:

mkdir -p pa/
mixcr postanalysis individual \
    --metadata metadata.tsv \
    --default-downsampling count-reads-auto \
    --default-weight-function read \
    --only-productive \
    --chains IGH \
    --tables pa/pa.i.tsv \
    --preproc-tables pa/preproc.i.tsv \
    results/*.clns \
    pa/individual.json.gz

The meaning of specified options is the following:

--metadata
specified metadata file to use
--default-downsampling
downsampling applied to normalize the clonesets. Without appropriate normalization it is not possible to make a statistical comparisons between datasets. In the considered case we normalize data to the same number of reads, and this number is computed automatically based on the number of unique reads in each clone in each dataset. See reference for all downsampling options. Default downsampling may be overridden for individual metrics.
--default-weight-function
defines weight of each clonotype. Set read beacause there are no barcodes in the data.
--only-productive
drop clonotypes with out-of-frame CDR3 sequences or containing stop codons
--tables
path for postanalysis metrics in a tabular form
--preproc-tables
path for tabular summary of the applied downsampling and other samples preprocessing (for example filtering productive clonotypes)
--chains
Since only IGH chain is present in the samples we can specify it directly.

After execution, we will have the following files:

> ls pa/

# gzipped JSON with all results 
individual.json.gz

# summary of applied preprocessors
preproc.i.IGH.tsv

# diversity tables
pa.i.diversity.IGH.tsv

# CDR3 metrics tables & CDR3 properties
pa.i.cdr3metrics.IGH.tsv

# V- / J- / VJ- usage tables
pa.i.vUsage.IGH.tsv
pa.i.JUsage.IGH.tsv
pa.i.VJUsage.IGH.tsv

# Isotype usage table
pa.i.IsotypeUsage.IGH.tsv

#V Spectratype tables
pa.i.VSpectratype.IGH.tsv
pa.i.VSpectratypeMean.IGH.tsv

Preprocessing summary tables (e.g. preproc.i.IGH.tsv) contain detailed information on how downsampling was applied for each metric (the table bellow shows first 10 rows):

characteristic sample preprocessor nElementsBefore sumWeightBefore nElementsAfter sumWeightAfter preprocessor#1 nElementsBefore#1 sumWeightBefore#1 nElementsAfter#1 sumWeightAfter#1 preprocessor#2 nElementsBefore#2 sumWeightBefore#2 nElementsAfter#2 sumWeightAfter#2 preprocessor#3 nElementsBefore#3 sumWeightBefore#3 nElementsAfter#3 sumWeightAfter#3 preprocessor#4 nElementsBefore#4 sumWeightBefore#4 nElementsAfter#4 sumWeightAfter#4
IsotypeUsage M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan nan
IsotypeUsage M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan nan
IsotypeUsage N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan nan
IsotypeUsage M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan nan
IsotypeUsage M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan nan
See full preprocessing summary:
characteristic sample preprocessor nElementsBefore sumWeightBefore nElementsAfter sumWeightAfter preprocessor#1 nElementsBefore#1 sumWeightBefore#1 nElementsAfter#1 sumWeightAfter#1 preprocessor#2 nElementsBefore#2 sumWeightBefore#2 nElementsAfter#2 sumWeightAfter#2 preprocessor#3 nElementsBefore#3 sumWeightBefore#3 nElementsAfter#3 sumWeightAfter#3 preprocessor#4 nElementsBefore#4 sumWeightBefore#4 nElementsAfter#4 sumWeightAfter#4
IsotypeUsage M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
IsotypeUsage M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
IsotypeUsage N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
IsotypeUsage M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
IsotypeUsage M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
IsotypeUsage M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
IsotypeUsage M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
IsotypeUsage N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
IsotypeUsage M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
IsotypeUsage M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
IsotypeUsage N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
IsotypeUsage N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
IsotypeUsage M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
IsotypeUsage N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
IsotypeUsage M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
IsotypeUsage M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
IsotypeUsage M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
IsotypeUsage M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
IsotypeUsage M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
IsotypeUsage M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
IsotypeUsage N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
IsotypeUsage M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
IsotypeUsage M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
IsotypeUsage N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
IsotypeUsage M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
IsotypeUsage N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
IsotypeUsage N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
IsotypeUsage N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
IsotypeUsage M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
IsotypeUsage N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
IsotypeUsage M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
IsotypeUsage M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
IsotypeUsage M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
IsotypeUsage M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
IsotypeUsage M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
IsotypeUsage M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
IsotypeUsage M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
IsotypeUsage M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
IsotypeUsage M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
IsotypeUsage M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
IsotypeUsage N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
IsotypeUsage M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
IsotypeUsage M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
IsotypeUsage M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
VSegmentUsage M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
VSegmentUsage M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
VSegmentUsage N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
VSegmentUsage M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
VSegmentUsage M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
VSegmentUsage M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
VSegmentUsage M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
VSegmentUsage N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
VSegmentUsage M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
VSegmentUsage M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
VSegmentUsage N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
VSegmentUsage N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
VSegmentUsage M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
VSegmentUsage N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
VSegmentUsage M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
VSegmentUsage M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
VSegmentUsage M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
VSegmentUsage M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
VSegmentUsage M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
VSegmentUsage M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
VSegmentUsage N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
VSegmentUsage M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
VSegmentUsage M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
VSegmentUsage N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
VSegmentUsage M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
VSegmentUsage N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
VSegmentUsage N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
VSegmentUsage N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
VSegmentUsage M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
VSegmentUsage N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
VSegmentUsage M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
VSegmentUsage M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
VSegmentUsage M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
VSegmentUsage M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
VSegmentUsage M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
VSegmentUsage M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
VSegmentUsage M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
VSegmentUsage M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
VSegmentUsage M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
VSegmentUsage M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
VSegmentUsage N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
VSegmentUsage M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
VSegmentUsage M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
VSegmentUsage M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
JSegmentUsage M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
JSegmentUsage M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
JSegmentUsage N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
JSegmentUsage M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
JSegmentUsage M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
JSegmentUsage M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
JSegmentUsage M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
JSegmentUsage N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
JSegmentUsage M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
JSegmentUsage M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
JSegmentUsage N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
JSegmentUsage N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
JSegmentUsage M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
JSegmentUsage N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
JSegmentUsage M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
JSegmentUsage M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
JSegmentUsage M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
JSegmentUsage M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
JSegmentUsage M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
JSegmentUsage M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
JSegmentUsage N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
JSegmentUsage M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
JSegmentUsage M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
JSegmentUsage N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
JSegmentUsage M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
JSegmentUsage N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
JSegmentUsage N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
JSegmentUsage N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
JSegmentUsage M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
JSegmentUsage N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
JSegmentUsage M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
JSegmentUsage M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
JSegmentUsage M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
JSegmentUsage M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
JSegmentUsage M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
JSegmentUsage M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
JSegmentUsage M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
JSegmentUsage M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
JSegmentUsage M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
JSegmentUsage M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
JSegmentUsage N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
JSegmentUsage M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
JSegmentUsage M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
JSegmentUsage M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
Charge M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Charge M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Charge N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Charge M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
Charge M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
Charge M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
Charge M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
Charge N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
Charge M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
Charge M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
Charge N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
Charge N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
Charge M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
Charge N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
Charge M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
Charge M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
Charge M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
Charge M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
Charge M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
Charge M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
Charge N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
Charge M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
Charge M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
Charge N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
Charge M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
Charge N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
Charge N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
Charge N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
Charge M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
Charge N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
Charge M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
Charge M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
Charge M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
Charge M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
Charge M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
Charge M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
Charge M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
Charge M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Charge M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
Charge M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
Charge N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Charge M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
Charge M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
Charge M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
Hydrophobicity M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Hydrophobicity M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Hydrophobicity N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Hydrophobicity M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
Hydrophobicity M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
Hydrophobicity M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
Hydrophobicity M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
Hydrophobicity N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
Hydrophobicity M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
Hydrophobicity M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
Hydrophobicity N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
Hydrophobicity N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
Hydrophobicity M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
Hydrophobicity N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
Hydrophobicity M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
Hydrophobicity M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
Hydrophobicity M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
Hydrophobicity M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
Hydrophobicity M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
Hydrophobicity M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
Hydrophobicity N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
Hydrophobicity M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
Hydrophobicity M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
Hydrophobicity N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
Hydrophobicity M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
Hydrophobicity N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
Hydrophobicity N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
Hydrophobicity N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
Hydrophobicity M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
Hydrophobicity N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
Hydrophobicity M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
Hydrophobicity M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
Hydrophobicity M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
Hydrophobicity M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
Hydrophobicity M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
Hydrophobicity M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
Hydrophobicity M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
Hydrophobicity M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Hydrophobicity M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
Hydrophobicity M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
Hydrophobicity N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Hydrophobicity M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
Hydrophobicity M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
Hydrophobicity M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
CDR3 spectratype M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
CDR3 spectratype M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
CDR3 spectratype N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
CDR3 spectratype M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
CDR3 spectratype M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
CDR3 spectratype M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
CDR3 spectratype M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
CDR3 spectratype N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
CDR3 spectratype M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
CDR3 spectratype M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
CDR3 spectratype N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
CDR3 spectratype N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
CDR3 spectratype M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
CDR3 spectratype N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
CDR3 spectratype M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
CDR3 spectratype M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
CDR3 spectratype M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
CDR3 spectratype M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
CDR3 spectratype M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
CDR3 spectratype M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
CDR3 spectratype N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
CDR3 spectratype M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
CDR3 spectratype M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
CDR3 spectratype N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
CDR3 spectratype M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
CDR3 spectratype N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
CDR3 spectratype N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
CDR3 spectratype N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
CDR3 spectratype M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
CDR3 spectratype N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
CDR3 spectratype M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
CDR3 spectratype M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
CDR3 spectratype M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
CDR3 spectratype M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
CDR3 spectratype M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
CDR3 spectratype M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
CDR3 spectratype M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
CDR3 spectratype M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
CDR3 spectratype M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
CDR3 spectratype M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
CDR3 spectratype N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
CDR3 spectratype M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
CDR3 spectratype M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
CDR3 spectratype M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
Surface M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Surface M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Surface N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Surface M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
Surface M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
Surface M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
Surface M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
Surface N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
Surface M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
Surface M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
Surface N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
Surface N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
Surface M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
Surface N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
Surface M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
Surface M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
Surface M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
Surface M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
Surface M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
Surface M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
Surface N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
Surface M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
Surface M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
Surface N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
Surface M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
Surface N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
Surface N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
Surface N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
Surface M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
Surface N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
Surface M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
Surface M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
Surface M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
Surface M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
Surface M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
Surface M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
Surface M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
Surface M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Surface M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
Surface M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
Surface N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Surface M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
Surface M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
Surface M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
VSpectratypeMean M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
VSpectratypeMean M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
VSpectratypeMean N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
VSpectratypeMean M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
VSpectratypeMean M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
VSpectratypeMean M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
VSpectratypeMean M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
VSpectratypeMean N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
VSpectratypeMean M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
VSpectratypeMean M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
VSpectratypeMean N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
VSpectratypeMean N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
VSpectratypeMean M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
VSpectratypeMean N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
VSpectratypeMean M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
VSpectratypeMean M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
VSpectratypeMean M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
VSpectratypeMean M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
VSpectratypeMean M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
VSpectratypeMean M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
VSpectratypeMean N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
VSpectratypeMean M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
VSpectratypeMean M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
VSpectratypeMean N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
VSpectratypeMean M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
VSpectratypeMean N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
VSpectratypeMean N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
VSpectratypeMean N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
VSpectratypeMean M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
VSpectratypeMean N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
VSpectratypeMean M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
VSpectratypeMean M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
VSpectratypeMean M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
VSpectratypeMean M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
VSpectratypeMean M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
VSpectratypeMean M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
VSpectratypeMean M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
VSpectratypeMean M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
VSpectratypeMean M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
VSpectratypeMean M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
VSpectratypeMean N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
VSpectratypeMean M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
VSpectratypeMean M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
VSpectratypeMean M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
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Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
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Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Diversity Efron-Thisted estimate/Shannon-Wiener diversity/Chao1 estimate/Inverse Simpson index/Normalized Shannon-Wiener index/Gini index/Observed diversity M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
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Volume M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Volume M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Volume N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Volume M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
Volume M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
Volume M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
Volume M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
Volume N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
Volume M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
Volume M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
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Volume M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
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Volume M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
Volume M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
Volume M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
Volume M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
Volume M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
Volume N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
Volume M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
Volume M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
Volume N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
Volume M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
Volume N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
Volume N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
Volume N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
Volume M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
Volume N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
Volume M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
Volume M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
Volume M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
Volume M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
Volume M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
Volume M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
Volume M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
Volume M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Volume M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
Volume M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
Volume N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Volume M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
Volume M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
Volume M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
Added N, nt M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Added N, nt M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Added N, nt N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Added N, nt M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
Added N, nt M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
Added N, nt M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
Added N, nt M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
Added N, nt N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
Added N, nt M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
Added N, nt M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
Added N, nt N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
Added N, nt N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
Added N, nt M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
Added N, nt N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
Added N, nt M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
Added N, nt M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
Added N, nt M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
Added N, nt M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
Added N, nt M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
Added N, nt M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
Added N, nt N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
Added N, nt M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
Added N, nt M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
Added N, nt N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
Added N, nt M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
Added N, nt N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
Added N, nt N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
Added N, nt N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
Added N, nt M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
Added N, nt N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
Added N, nt M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
Added N, nt M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
Added N, nt M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
Added N, nt M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
Added N, nt M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
Added N, nt M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
Added N, nt M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
Added N, nt M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Added N, nt M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
Added N, nt M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
Added N, nt N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Added N, nt M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
Added N, nt M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
Added N, nt M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
CDR3 length, nt M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
CDR3 length, nt M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
CDR3 length, nt N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
CDR3 length, nt M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
CDR3 length, nt M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
CDR3 length, nt M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
CDR3 length, nt M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
CDR3 length, nt N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
CDR3 length, nt M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
CDR3 length, nt M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
CDR3 length, nt N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
CDR3 length, nt N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
CDR3 length, nt M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
CDR3 length, nt N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
CDR3 length, nt M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
CDR3 length, nt M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
CDR3 length, nt M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
CDR3 length, nt M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
CDR3 length, nt M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
CDR3 length, nt M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
CDR3 length, nt N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
CDR3 length, nt M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
CDR3 length, nt M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
CDR3 length, nt N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
CDR3 length, nt M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
CDR3 length, nt N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
CDR3 length, nt N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
CDR3 length, nt N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
CDR3 length, nt M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
CDR3 length, nt N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
CDR3 length, nt M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
CDR3 length, nt M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
CDR3 length, nt M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
CDR3 length, nt M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
CDR3 length, nt M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
CDR3 length, nt M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
CDR3 length, nt M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
CDR3 length, nt M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
CDR3 length, nt M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
CDR3 length, nt M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
CDR3 length, nt N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
CDR3 length, nt M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
CDR3 length, nt M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
CDR3 length, nt M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
VJSegmentUsage M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
VJSegmentUsage M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
VJSegmentUsage N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
VJSegmentUsage M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
VJSegmentUsage M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
VJSegmentUsage M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
VJSegmentUsage M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
VJSegmentUsage N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
VJSegmentUsage M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
VJSegmentUsage M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
VJSegmentUsage N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
VJSegmentUsage N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
VJSegmentUsage M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
VJSegmentUsage N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
VJSegmentUsage M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
VJSegmentUsage M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
VJSegmentUsage M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
VJSegmentUsage M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
VJSegmentUsage M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
VJSegmentUsage M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
VJSegmentUsage N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
VJSegmentUsage M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
VJSegmentUsage M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
VJSegmentUsage N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
VJSegmentUsage M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
VJSegmentUsage N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
VJSegmentUsage N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
VJSegmentUsage N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
VJSegmentUsage M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
VJSegmentUsage N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
VJSegmentUsage M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
VJSegmentUsage M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
VJSegmentUsage M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
VJSegmentUsage M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
VJSegmentUsage M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
VJSegmentUsage M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
VJSegmentUsage M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
VJSegmentUsage M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
VJSegmentUsage M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
VJSegmentUsage M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
VJSegmentUsage N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
VJSegmentUsage M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
VJSegmentUsage M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
VJSegmentUsage M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
VSpectratype M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
VSpectratype M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
VSpectratype N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
VSpectratype M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
VSpectratype M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
VSpectratype M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
VSpectratype M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
VSpectratype N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
VSpectratype M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
VSpectratype M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
VSpectratype N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
VSpectratype N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
VSpectratype M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
VSpectratype N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
VSpectratype M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
VSpectratype M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
VSpectratype M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
VSpectratype M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
VSpectratype M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
VSpectratype M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
VSpectratype N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
VSpectratype M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
VSpectratype M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
VSpectratype N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
VSpectratype M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
VSpectratype N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
VSpectratype N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
VSpectratype N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
VSpectratype M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
VSpectratype N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
VSpectratype M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
VSpectratype M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
VSpectratype M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
VSpectratype M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
VSpectratype M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
VSpectratype M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
VSpectratype M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
VSpectratype M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
VSpectratype M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
VSpectratype M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
VSpectratype N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
VSpectratype M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
VSpectratype M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
VSpectratype M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
NDN length, nt M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
NDN length, nt M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
NDN length, nt N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
NDN length, nt M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
NDN length, nt M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
NDN length, nt M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
NDN length, nt M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
NDN length, nt N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
NDN length, nt M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
NDN length, nt M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
NDN length, nt N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
NDN length, nt N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
NDN length, nt M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
NDN length, nt N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
NDN length, nt M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
NDN length, nt M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
NDN length, nt M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
NDN length, nt M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
NDN length, nt M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
NDN length, nt M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
NDN length, nt N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
NDN length, nt M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
NDN length, nt M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
NDN length, nt N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
NDN length, nt M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
NDN length, nt N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
NDN length, nt N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
NDN length, nt N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
NDN length, nt M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
NDN length, nt N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
NDN length, nt M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
NDN length, nt M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
NDN length, nt M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
NDN length, nt M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
NDN length, nt M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
NDN length, nt M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
NDN length, nt M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
NDN length, nt M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
NDN length, nt M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
NDN length, nt M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
NDN length, nt N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
NDN length, nt M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
NDN length, nt M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
NDN length, nt M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
d50 M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 72121 1.12077e+06 1551 62780 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 Cumulative top 50.0 30741
d50 M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 95523 648857 6462 62778 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 Cumulative top 50.0 45810
d50 N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 92761 1.11126e+06 1394 62775 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 Cumulative top 50.0 33352
d50 M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 1910 1.54254e+06 20 63284 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 Cumulative top 50.0 653
d50 M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 8848 248064 29 63275 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 Cumulative top 50.0 6784
d50 M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 83727 353453 3450 62776 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 Cumulative top 50.0 43786
d50 M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 5703 14611 459 6906 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 Cumulative top 50.0 5256
d50 N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 65294 271110 1793 62778 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 Cumulative top 50.0 38846
d50 M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 8799 846111 401 62798 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 Cumulative top 50.0 5855
d50 M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 208134 3.32206e+06 192 62818 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 Cumulative top 50.0 25345
d50 N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 32902 104257 5809 47944 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 Cumulative top 50.0 29813
d50 N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 112864 309918 8154 62775 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 Cumulative top 50.0 61183
d50 M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 1453 1.54974e+06 23 63107 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 Cumulative top 50.0 570
d50 N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 71252 405065 9031 62778 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 Cumulative top 50.0 44077
d50 M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 70091 1.56128e+06 187 62786 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 Cumulative top 50.0 20264
d50 M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 109676 3.11773e+06 192 62825 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 Cumulative top 50.0 21437
d50 M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 4320 512431 15 64643 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 Cumulative top 50.0 2964
d50 M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 56039 328221 2738 62779 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 Cumulative top 50.0 34706
d50 M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 73450 538465 4034 62775 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 Cumulative top 50.0 36431
d50 M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 15079 291618 835 62796 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 Cumulative top 50.0 11314
d50 N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 137249 323560 8121 62776 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 Cumulative top 50.0 65141
d50 M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 54707 495753 500 62778 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 Cumulative top 50.0 26356
d50 M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 81594 448685 1043 62778 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 Cumulative top 50.0 34930
d50 N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 66527 255193 1843 62778 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 Cumulative top 50.0 40241
d50 M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 7045 638013 377 62775 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 Cumulative top 50.0 4869
d50 N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 52671 823950 6124 62778 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 Cumulative top 50.0 31986
d50 N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 71765 466036 8923 62776 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 Cumulative top 50.0 43718
d50 N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 228959 1.08921e+06 8473 62775 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 Cumulative top 50.0 62650
d50 M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 57007 134123 4158 62775 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 Cumulative top 50.0 52279
d50 N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 49922 254254 1502 62776 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 Cumulative top 50.0 33366
d50 M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 325 3531 2 1826 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 Cumulative top 50.0 303
d50 M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 2396 1.46567e+06 79 63023 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 Cumulative top 50.0 1112
d50 M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 57445 355874 2799 62778 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 Cumulative top 50.0 34623
d50 M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 5747 699641 16 64880 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 Cumulative top 50.0 3475
d50 M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 44577 189592 930 62779 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 Cumulative top 50.0 33012
d50 M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 14282 797243 29 62873 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 Cumulative top 50.0 7173
d50 M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 66165 982689 465 62778 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 Cumulative top 50.0 24884
d50 M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 1325 69980 17 34887 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 Cumulative top 50.0 1176
d50 M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 81670 969933 1565 62775 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 Cumulative top 50.0 30804
d50 M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 16665 683973 848 62798 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 Cumulative top 50.0 11082
d50 N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 120978 291716 6952 62776 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 Cumulative top 50.0 62326
d50 M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 1419 65516 16 31943 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 Cumulative top 50.0 1248
d50 M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 2151 1.6681e+06 60 63262 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 Cumulative top 50.0 676
d50 M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic Cumulative top 50.0 87256 693306 179 62840 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 Cumulative top 50.0 24175
Strength M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
Strength M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
Strength N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
Strength M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
Strength M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
Strength M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
Strength M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
Strength N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
Strength M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
Strength M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
Strength N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
Strength N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
Strength M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
Strength N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
Strength M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
Strength M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
Strength M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
Strength M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
Strength M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
Strength M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
Strength N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
Strength M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
Strength M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
Strength N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
Strength M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
Strength N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
Strength N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
Strength N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
Strength M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
Strength N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
Strength M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
Strength M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
Strength M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
Strength M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
Strength M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
Strength M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
Strength M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
Strength M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
Strength M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
Strength M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
Strength N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
Strength M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
Strength M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
Strength M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan
CDR3 length, aa M2_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 72121 1.12077e+06 30741 125550 Filter IGH chains 72121 1.12077e+06 72121 1.12077e+06 Filter stops in CDR3, OOF in CDR3 72121 1.12077e+06 64734 1.02411e+06 Downsample automatic 64734 1.02411e+06 30741 125550 nan nan
CDR3 length, aa M2_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 95523 648857 45810 125550 Filter IGH chains 95523 648857 95523 648857 Filter stops in CDR3, OOF in CDR3 95523 648857 86623 601517 Downsample automatic 86623 601517 45810 125550 nan nan
CDR3 length, aa N1_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 92761 1.11126e+06 33352 125550 Filter IGH chains 92761 1.11126e+06 92761 1.11126e+06 Filter stops in CDR3, OOF in CDR3 92761 1.11126e+06 83364 1.01962e+06 Downsample automatic 83364 1.01962e+06 33352 125550 nan nan
CDR3 length, aa M1_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1910 1.54254e+06 653 125550 Filter IGH chains 1910 1.54254e+06 1910 1.54254e+06 Filter stops in CDR3, OOF in CDR3 1910 1.54254e+06 1771 1.32039e+06 Downsample automatic 1771 1.32039e+06 653 125550 nan nan
CDR3 length, aa M4_4T1_DLN_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8848 248064 6784 125550 Filter IGH chains 8848 248064 8848 248064 Filter stops in CDR3, OOF in CDR3 8848 248064 8103 240731 Downsample automatic 8103 240731 6784 125550 nan nan
CDR3 length, aa M2_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 83727 353453 43786 125550 Filter IGH chains 83727 353453 83727 353453 Filter stops in CDR3, OOF in CDR3 83727 353453 76470 331794 Downsample automatic 76470 331794 43786 125550 nan nan
CDR3 length, aa M4_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5703 14611 5256 13808 Filter IGH chains 5703 14611 5703 14611 Filter stops in CDR3, OOF in CDR3 5703 14611 5256 13808 Downsample automatic 5256 13808 5256 13808 nan nan
CDR3 length, aa N2_control_BM_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 65294 271110 38846 125550 Filter IGH chains 65294 271110 65294 271110 Filter stops in CDR3, OOF in CDR3 65294 271110 59555 254772 Downsample automatic 59555 254772 38846 125550 nan nan
CDR3 length, aa M3_4T1_DLN_S12.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 8799 846111 5855 125550 Filter IGH chains 8799 846111 8799 846111 Filter stops in CDR3, OOF in CDR3 8799 846111 8124 810198 Downsample automatic 8124 810198 5855 125550 nan nan
CDR3 length, aa M1_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 208134 3.32206e+06 25345 125550 Filter IGH chains 208134 3.32206e+06 208134 3.32206e+06 Filter stops in CDR3, OOF in CDR3 208134 3.32206e+06 194979 3.23364e+06 Downsample automatic 194979 3.23364e+06 25345 125550 nan nan
CDR3 length, aa N1_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 32902 104257 29813 95884 Filter IGH chains 32902 104257 32902 104257 Filter stops in CDR3, OOF in CDR3 32902 104257 29813 95884 Downsample automatic 29813 95884 29813 95884 nan nan
CDR3 length, aa N1_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 112864 309918 61183 125550 Filter IGH chains 112864 309918 112864 309918 Filter stops in CDR3, OOF in CDR3 112864 309918 103169 285540 Downsample automatic 103169 285540 61183 125550 nan nan
CDR3 length, aa M1_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1453 1.54974e+06 570 125550 Filter IGH chains 1453 1.54974e+06 1453 1.54974e+06 Filter stops in CDR3, OOF in CDR3 1453 1.54974e+06 1317 1.37634e+06 Downsample automatic 1317 1.37634e+06 570 125550 nan nan
CDR3 length, aa N2_control_LN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71252 405065 44077 125550 Filter IGH chains 71252 405065 71252 405065 Filter stops in CDR3, OOF in CDR3 71252 405065 64152 373080 Downsample automatic 64152 373080 44077 125550 nan nan
CDR3 length, aa M1_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 70091 1.56128e+06 20264 125550 Filter IGH chains 70091 1.56128e+06 70091 1.56128e+06 Filter stops in CDR3, OOF in CDR3 70091 1.56128e+06 62434 1.48481e+06 Downsample automatic 62434 1.48481e+06 20264 125550 nan nan
CDR3 length, aa M1_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 109676 3.11773e+06 21437 125550 Filter IGH chains 109676 3.11773e+06 109676 3.11773e+06 Filter stops in CDR3, OOF in CDR3 109676 3.11773e+06 99507 2.97244e+06 Downsample automatic 99507 2.97244e+06 21437 125550 nan nan
CDR3 length, aa M3_4T1_Tumor_S14.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 4320 512431 2964 125550 Filter IGH chains 4320 512431 4320 512431 Filter stops in CDR3, OOF in CDR3 4320 512431 3906 461283 Downsample automatic 3906 461283 2964 125550 nan nan
CDR3 length, aa M3_4T1_Blood_S9.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 56039 328221 34706 125550 Filter IGH chains 56039 328221 56039 328221 Filter stops in CDR3, OOF in CDR3 56039 328221 51004 308539 Downsample automatic 51004 308539 34706 125550 nan nan
CDR3 length, aa M2_4T1_DLN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 73450 538465 36431 125550 Filter IGH chains 73450 538465 73450 538465 Filter stops in CDR3, OOF in CDR3 73450 538465 66967 499321 Downsample automatic 66967 499321 36431 125550 nan nan
CDR3 length, aa M4_4T1_Blood_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 15079 291618 11314 125550 Filter IGH chains 15079 291618 15079 291618 Filter stops in CDR3, OOF in CDR3 15079 291618 13478 273168 Downsample automatic 13478 273168 11314 125550 nan nan
CDR3 length, aa N2_control_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 137249 323560 65141 125550 Filter IGH chains 137249 323560 137249 323560 Filter stops in CDR3, OOF in CDR3 137249 323560 126369 307798 Downsample automatic 126369 307798 65141 125550 nan nan
CDR3 length, aa M3_4T1_BM_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 54707 495753 26356 125550 Filter IGH chains 54707 495753 54707 495753 Filter stops in CDR3, OOF in CDR3 54707 495753 50774 478430 Downsample automatic 50774 478430 26356 125550 nan nan
CDR3 length, aa M1_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81594 448685 34930 125550 Filter IGH chains 81594 448685 81594 448685 Filter stops in CDR3, OOF in CDR3 81594 448685 75154 426604 Downsample automatic 75154 426604 34930 125550 nan nan
CDR3 length, aa N2_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66527 255193 40241 125550 Filter IGH chains 66527 255193 66527 255193 Filter stops in CDR3, OOF in CDR3 66527 255193 60693 239781 Downsample automatic 60693 239781 40241 125550 nan nan
CDR3 length, aa M3_4T1_DLN_S11.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 7045 638013 4869 125550 Filter IGH chains 7045 638013 7045 638013 Filter stops in CDR3, OOF in CDR3 7045 638013 6550 613148 Downsample automatic 6550 613148 4869 125550 nan nan
CDR3 length, aa N1_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 52671 823950 31986 125550 Filter IGH chains 52671 823950 52671 823950 Filter stops in CDR3, OOF in CDR3 52671 823950 47041 754429 Downsample automatic 47041 754429 31986 125550 nan nan
CDR3 length, aa N2_control_LN_S3.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 71765 466036 43718 125550 Filter IGH chains 71765 466036 71765 466036 Filter stops in CDR3, OOF in CDR3 71765 466036 64445 428849 Downsample automatic 64445 428849 43718 125550 nan nan
CDR3 length, aa N1_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 228959 1.08921e+06 62650 125550 Filter IGH chains 228959 1.08921e+06 228959 1.08921e+06 Filter stops in CDR3, OOF in CDR3 228959 1.08921e+06 205257 1.00294e+06 Downsample automatic 205257 1.00294e+06 62650 125550 nan nan
CDR3 length, aa M2_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57007 134123 52279 125550 Filter IGH chains 57007 134123 57007 134123 Filter stops in CDR3, OOF in CDR3 57007 134123 52279 125550 Downsample automatic 52279 125550 52279 125550 nan nan
CDR3 length, aa N1_control_BM_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 49922 254254 33366 125550 Filter IGH chains 49922 254254 49922 254254 Filter stops in CDR3, OOF in CDR3 49922 254254 45458 234149 Downsample automatic 45458 234149 33366 125550 nan nan
CDR3 length, aa M4_4T1_Tumor_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 325 3531 303 3429 Filter IGH chains 325 3531 325 3531 Filter stops in CDR3, OOF in CDR3 325 3531 303 3429 Downsample automatic 303 3429 303 3429 nan nan
CDR3 length, aa M2_4T1_Tumor_S1.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2396 1.46567e+06 1112 125550 Filter IGH chains 2396 1.46567e+06 2396 1.46567e+06 Filter stops in CDR3, OOF in CDR3 2396 1.46567e+06 2118 744281 Downsample automatic 2118 744281 1112 125550 nan nan
CDR3 length, aa M3_4T1_Blood_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 57445 355874 34623 125550 Filter IGH chains 57445 355874 57445 355874 Filter stops in CDR3, OOF in CDR3 57445 355874 52337 335414 Downsample automatic 52337 335414 34623 125550 nan nan
CDR3 length, aa M3_4T1_Tumor_S13.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 5747 699641 3475 125550 Filter IGH chains 5747 699641 5747 699641 Filter stops in CDR3, OOF in CDR3 5747 699641 5303 630141 Downsample automatic 5303 630141 3475 125550 nan nan
CDR3 length, aa M1_4T1_Blood_S6.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 44577 189592 33012 125550 Filter IGH chains 44577 189592 44577 189592 Filter stops in CDR3, OOF in CDR3 44577 189592 41177 180061 Downsample automatic 41177 180061 33012 125550 nan nan
CDR3 length, aa M4_4T1_DLN_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 14282 797243 7173 125550 Filter IGH chains 14282 797243 14282 797243 Filter stops in CDR3, OOF in CDR3 14282 797243 13288 771844 Downsample automatic 13288 771844 7173 125550 nan nan
CDR3 length, aa M3_4T1_BM_S8.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 66165 982689 24884 125550 Filter IGH chains 66165 982689 66165 982689 Filter stops in CDR3, OOF in CDR3 66165 982689 61299 948117 Downsample automatic 61299 948117 24884 125550 nan nan
CDR3 length, aa M4_4T1_BM_S10.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1325 69980 1176 67946 Filter IGH chains 1325 69980 1325 69980 Filter stops in CDR3, OOF in CDR3 1325 69980 1176 67946 Downsample automatic 1176 67946 1176 67946 nan nan
CDR3 length, aa M2_4T1_BM_S4.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 81670 969933 30804 125550 Filter IGH chains 81670 969933 81670 969933 Filter stops in CDR3, OOF in CDR3 81670 969933 74689 885711 Downsample automatic 74689 885711 30804 125550 nan nan
CDR3 length, aa M4_4T1_Blood_S2.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 16665 683973 11082 125550 Filter IGH chains 16665 683973 16665 683973 Filter stops in CDR3, OOF in CDR3 16665 683973 14910 642701 Downsample automatic 14910 642701 11082 125550 nan nan
CDR3 length, aa N2_control_Blood_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 120978 291716 62326 125550 Filter IGH chains 120978 291716 120978 291716 Filter stops in CDR3, OOF in CDR3 120978 291716 111287 277661 Downsample automatic 111287 277661 62326 125550 nan nan
CDR3 length, aa M4_4T1_BM_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 1419 65516 1248 63267 Filter IGH chains 1419 65516 1419 65516 Filter stops in CDR3, OOF in CDR3 1419 65516 1248 63267 Downsample automatic 1248 63267 1248 63267 nan nan
CDR3 length, aa M2_4T1_Tumor_S5.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 2151 1.6681e+06 676 125550 Filter IGH chains 2151 1.6681e+06 2151 1.6681e+06 Filter stops in CDR3, OOF in CDR3 2151 1.6681e+06 1922 1.1274e+06 Downsample automatic 1922 1.1274e+06 676 125550 nan nan
CDR3 length, aa M1_4T1_DLN_S7.clns Filter IGH chains Filter stops in CDR3, OOF in CDR3 Downsample automatic 87256 693306 24175 125550 Filter IGH chains 87256 693306 87256 693306 Filter stops in CDR3, OOF in CDR3 87256 693306 81881 674356 Downsample automatic 81881 674356 24175 125550 nan nan

Columns explained:

characteristic
metrics name (ex.IsotypeUsage)
sample
name of the .clns file (ex. M2_4T1_BM_S8.clns)
preprocessor

the name of the overall preprocessors chain applied to the dataset. FilterIGHchains|FilterstopsinCDR3,OOFinCDR3|Downsampleautomatic means the data has been subjected to three consecutive preprocessors:

  • Only IGH chains were filtered
  • Non-functional clonotypes containing stop-codons and OOF clones were filltered out and only functional were left
  • Automatic Downsampling function has been applied to normalize sample sizes
nElementsBefore
number of clonotypes before any preprocessing applied (that is in the initial dataset) (ex. 72121 clones)
sumWeightBefore
total weight of all clonotypes before any preprocessing applied. The weight may be either number of reads, UMIs or cells, depending on the selected downsampling. In this case it represents the total number of reads that contribute to clonotypes (ex.1120769 reads)
nElementsAfter
number of clonotypes in the dataset after all preprocessors have been applied (ex.30741 clones)
sumWeightBefore
total weight of all clonotypes after all preprocessors have been applied (ex. 125550). Note that all samples will have the same value for sumWeightBefore in this case, because downsampling was applied, thus all samples have been normalized to the same weight.
preprocessor#i
i-th part of the preprocessing chain (ex. preprocessor#1: Filter IGH chains)
nElementsBefore#i
number of clonotypes before i-th preprocessor has been applied (ex. nElementsBefore#1: 72121)
sumWeightBefore#i
total weight of all clonotypes before i-th preprocessor has been applied (ex. sumWeightBefore#1: 1120769)
nElementsAfter#i
number of clonotypes after i-th preprocessor has been applied (ex. nElementsAfter#1: 30741)
sumWeightAfter#i
total weight of all clonotypes after i-th preprocessor has been applied (ex. sumWeightAfter#1: 125550)

. . .

Various postanalysis tables contain information about each metric computed for each sample. For example, let's have a look inside pa.i.JUsage.IGH.tsv. This table contains frequencies for each J segment present in the sample :

sample IGHJ3*00 IGHJ2*00 IGHJ1*00 IGHJ4*00
M1_4T1_Blood_S2.clns 0.246786 0.356726 0.12035 0.276137
M1_4T1_Blood_S6.clns 0.243162 0.376105 0.129136 0.251597
M1_4T1_BM_S4.clns 0.244986 0.288722 0.134162 0.332131
M1_4T1_BM_S8.clns 0.248443 0.286109 0.133891 0.331557
M1_4T1_DLN_S3.clns 0.247447 0.256957 0.0684667 0.427129
See full JUsage summary:
sample IGHJ3*00 IGHJ2*00 IGHJ1*00 IGHJ4*00
M1_4T1_Blood_S2.clns 0.246786 0.356726 0.12035 0.276137
M1_4T1_Blood_S6.clns 0.243162 0.376105 0.129136 0.251597
M1_4T1_BM_S4.clns 0.244986 0.288722 0.134162 0.332131
M1_4T1_BM_S8.clns 0.248443 0.286109 0.133891 0.331557
M1_4T1_DLN_S3.clns 0.247447 0.256957 0.0684667 0.427129
M1_4T1_DLN_S7.clns 0.248857 0.258463 0.0734209 0.419259
M1_4T1_Tumor_S1.clns 0.160438 0.437953 0.0869295 0.314679
M1_4T1_Tumor_S5.clns 0.147081 0.467153 0.0821744 0.303592
M2_4T1_Blood_S2.clns 0.267965 0.307965 0.12372 0.30035
M2_4T1_Blood_S6.clns 0.27311 0.309741 0.125161 0.291987
M2_4T1_BM_S4.clns 0.280486 0.248323 0.108156 0.363035
M2_4T1_BM_S8.clns 0.284094 0.256734 0.102987 0.356185
M2_4T1_DLN_S3.clns 0.253222 0.264261 0.105448 0.377069
M2_4T1_DLN_S7.clns 0.256623 0.267256 0.104389 0.371732
M2_4T1_Tumor_S1.clns 0.302971 0.352816 0.107192 0.237021
M2_4T1_Tumor_S5.clns 0.277913 0.279315 0.122748 0.320024
M3_4T1_Blood_S10.clns 0.266125 0.28814 0.115484 0.330251
M3_4T1_Blood_S9.clns 0.266149 0.290179 0.117993 0.325679
M3_4T1_BM_S7.clns 0.25417 0.27687 0.163656 0.305305
M3_4T1_BM_S8.clns 0.253413 0.274401 0.164166 0.308021
M3_4T1_DLN_S11.clns 0.309574 0.227646 0.117523 0.345257
M3_4T1_DLN_S12.clns 0.31405 0.24184 0.114504 0.329606
M3_4T1_Tumor_S13.clns 0.158829 0.304691 0.223011 0.313469
M3_4T1_Tumor_S14.clns 0.156145 0.300573 0.226937 0.316344
M4_4T1_Blood_S2.clns 0.273971 0.313684 0.112911 0.299434
M4_4T1_Blood_S7.clns 0.269566 0.320542 0.11264 0.297252
M4_4T1_BM_S10.clns 0.371295 0.176581 0.115386 0.336738
M4_4T1_BM_S5.clns 0.359034 0.180552 0.111954 0.34846
M4_4T1_DLN_S4.clns 0.327861 0.270115 0.0523696 0.349654
M4_4T1_DLN_S9.clns 0.327949 0.27139 0.0540661 0.346595
M4_4T1_Tumor_S1.clns 0.266947 0.359864 0.121886 0.251304
M4_4T1_Tumor_S6.clns 0.256926 0.489064 0.15923 0.0947798
N1_control_Blood_S5.clns 0.273309 0.267073 0.171127 0.288491
N1_control_Blood_S6.clns 0.28047 0.267384 0.160573 0.291573
N1_control_BM_S1.clns 0.219785 0.313803 0.211661 0.254751
N1_control_BM_S2.clns 0.224994 0.319737 0.199012 0.256256
N1_control_LN_S3.clns 0.29499 0.252346 0.0789327 0.373732
N1_control_LN_S4.clns 0.300092 0.250834 0.081755 0.367319
N2_control_Blood_S5.clns 0.292911 0.263106 0.183855 0.260127
N2_control_Blood_S6.clns 0.290418 0.264644 0.182589 0.26235
N2_control_BM_S1.clns 0.253206 0.335986 0.106133 0.304675
N2_control_BM_S2.clns 0.254879 0.333023 0.106818 0.305281
N2_control_LN_S3.clns 0.302174 0.235643 0.0809558 0.381227
N2_control_LN_S4.clns 0.306045 0.243911 0.0812903 0.368753

Graphical output

MiXCR allows to export graphical results in PDF, EPS, PNG and SVG formats using exportPlots command.

For diversity metrics and CDR3 properties MiXCR allows to group data in different ways according to the submitted metadata.tsv and apply various statistical tests for group comparison.

Diversity

Let's reconstruct one of the figures from the paper. Let's say we want to look at the Normalized ShannonWiener diversity index. We will group samples by tissues and use separate facets for contol and experiment group. That can be easily done with a single command:

mixcr exportPlots diversity \
    --metadata metadata.tsv \
    --plot-type boxplot \
    --metric normalizedShannonWienerIndex \
    --primary-group tissue \
    --facet-by condition \
    --primary-group-values Tumor,LN,DLN,Blood,BM \
    pa/individual.json.gz \
    figs/diversity.svg

diversity.IGH.svg

Arguments explained:

--metadata
metadata.tsv is the name of metadata file.
--plot-type
boxplot is the type of plot to generate. See mixcr exportPlots for other options.
--metric:
normalizedShannonWienerIndex is the name of the metric to visualize. See diversity metrics for other options. If not specified multiple plots will be generated for each available diversity metric.
--primary-group
tissue is name of the column with metadata values from metadata.tsv to group samples by.
--primary-group-values
Tumor,LN,DLN,Blood,BM represents the order of --primary-group values on the plot (tissue in this case)
--facet-by
condition is name of the column with metadata values from metadata.tsv to group samples and represent on separate facets for each group.
postanalysis/individual.json.gz
the name of gzipped JSON file with all postanalysis results generated by `mixcr postanalysis individual
normalizedShannonWienerIndex.pdf
the name of output file. Also specifies the extension of the output file. One can use one of the following graphical out formats: .pdf, .eps, .png and .svg.
V usage

Now lets look at the J gene distribution among all samples.

mixcr exportPlots vUsage \
  --metadata metadata.tsv \
  --chains IGH \
  --palette sequential \
  --color-key tissue \
  pa/individual.json.gz \
  figs/vUsage.pdf
--palette
sequential. Determines color palette to be used for the heatmap. See gene segment usage plots for other options.
--color-key
tissue. Metadata column name.

vUsage.IGH.svg

Overlap postanalysis

Two samples overlap

Since our samples were prepared in replicas, it is often usefully to check if clone frequencies correlate between replicas. Let's take two replicas of one biological sample and overlap two repertoires. We will use mixcr overlapScatterPlot function:

mixcr overlapScatterPlot \
    --downsampling none \
    --chains IGH \
    results/M1_4T1_replica1_Blood.clns \
    results/M1_4T1_replica2_Blood.clns \
    figs/overlap.pdf

overlap.png

All-vs-All overlap

MiXCR also allows performing an overall overlap analysis using mixcr postanalysis overlap. But here, since there are a lot of samples we want to actually overlap groups of samples. Running the following command will perform pairwise overlap comparison between groups of samples with different tissue and condition values.

mixcr postanalysis overlap \
    --factor-by tissue,condition \
    --metadata metadata.tsv \
    --default-downsampling count-reads-auto \
    --default-weight-function read \
    --only-productive \
    --tables pa/postanalysis.overlap.tsv \
    --preproc-tables pa/preproc.overlap.tsv \
    results/*.clns \
    pa/overlap.tissue_condition.json.gz
--factor-by
tissue,condition defines the set of metadata columns for which a list of unique intersections will be created and used for group comparison

Other arguments are same as for individual postanalysis mentioned above.

This command will generate a set of files:

#Tsv files for every metric
postanalysis.overlap.F1Index.IGH.tsv
postanalysis.overlap.F2Index.IGH.tsv
postanalysis.overlap.JaccardIndex.IGH.tsv
postanalysis.overlap.PearsonAll.IGH.tsv
postanalysis.overlap.Pearson.IGH.tsv
postanalysis.overlap.RelativeDiversity.IGH.tsv
postanalysis.overlap.SharedClonotypes.IGH.tsv

# summary of applied preprocessors
preproc.overlap.IGH.tsv

# gzipped JSON with all results 
overlap.tissue_condition.json.gz

The tabular output for example for F2 metric will look like:

sample Blood,4T1 BM,4T1 DLN,4T1 Tumor,4T1 Blood,control BM,control LN,control
Blood,4T1 1 0.123711 0.134151 0.357004 0.0477449 0.0576299 0.106747
BM,4T1 0.123711 1 0.0461159 0.115398 0.0728694 0.0295404 0.046996
DLN,4T1 0.134151 0.0461159 1 0.134484 0.0189902 0.0232703 0.0300021
Tumor,4T1 0.357004 0.115398 0.134484 1 0.0526398 0.0753527 0.128776
Blood,control 0.0477449 0.0728694 0.0189902 0.0526398 1 0.0592363 0.103798
BM,control 0.0576299 0.0295404 0.0232703 0.0753527 0.0592363 1 0.270242
LN,control 0.106747 0.046996 0.0300021 0.128776 0.103798 0.270242 1

Every overlap metric is also possible to present in a graphical format:

mixcr exportPlots overlap \
    --chains IGH \
    --palette density \
    --metric f2Index \
    pa/overlap.tissue_condition.json.gz \
    figs/overlap.tissue_condition.pdf
For list of available metrics see mixcr exportPlots overlap

overlap.tissue_condition.IGH.svg

For further details see overlap postanalysis reference.