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Multiplex BCR UMI cDNA libraries

For this tutorial we will use the data published in the following article:

Chen JS, Chow RD, Song E, Mao T, Israelow B, Kamath K, Bozekowski J, Haynes WA, Filler RB, Menasche BL, Wei J, Alfajaro MM, Song W, Peng L, Carter L, Weinstein JS, Gowthaman U, Chen S, Craft J, Shon JC, Iwasaki A, Wilen CB, Eisenbarth SC. High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells. Sci Immunol. 2022 Feb 4;7(68):eabl5652. doi: 10.1126/sciimmunol.abl5652. Epub 2022 Feb 4. PMID: 34914544; PMCID: PMC8977051.

Experiment setting

The experiment includes 8 mice that express angiotensin-converting enzyme 2 (ACE2) in epithelial cells thus vulnerable to SARS-CoV-2. 4 K18-hACE2 Bcl6fl/fl mice and 4 Bcl6fl/flCd4Cre (TFH cell deficiency model) mice. Mice were infected intranasally with SARS-CoV-2 (isolate USA-WA1/2020) and 14 days post-infection S-specific plasmablasts were isolated. RNA from spike-specific B cells was isolated using the RNeasy Plus Micro Kit (Qiagen) following the manufacturer’s instructions. BCR libraries were prepared using the NEBNext Single Cell/Low Input cDNA Synthesis & Amplification Module (New England Biolabs (NEB), E6421) and NEBNext Immune Sequencing Kit (NEB, E6330), with additional reagents provided by NEB to integrate the two kits. High-quality RNA (1 to 20 ng) with RNA integrity number ≥ 8 was used as input. Libraries were analyzed by Bioanalyzer High Sensitivity DNA assay, pooled in equal amounts with PhiX spike-in, and sequenced on an Illumina MiSeq using the V3 kit, with 325 base pairs (bp) for read 1 and 275 bp for read 2.

All data may be downloaded directly from SRA (PRJNA780318) using e.g. SRA Explorer.

Use aria2c for efficient download of the full dataset with the proper filenames:

download.sh
mkdir -p raw
aria2c -c -s 16 -x 16 -k 1M -j 8 -i download-list.txt
download-list.txt
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/022/SRR16943422/SRR16943422_1.fastq.gz
  out=raw/mouse_3_Cd4Cre_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/022/SRR16943422/SRR16943422_2.fastq.gz
  out=raw/mouse_3_Cd4Cre_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/025/SRR16943425/SRR16943425_1.fastq.gz
  out=raw/mouse_4_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/025/SRR16943425/SRR16943425_2.fastq.gz
  out=raw/mouse_4_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/028/SRR16943428/SRR16943428_1.fastq.gz
  out=raw/mouse_1_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/028/SRR16943428/SRR16943428_2.fastq.gz
  out=raw/mouse_1_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/021/SRR16943421/SRR16943421_1.fastq.gz
  out=raw/mouse_4_Cd4Cre_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/021/SRR16943421/SRR16943421_2.fastq.gz
  out=raw/mouse_4_Cd4Cre_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/023/SRR16943423/SRR16943423_1.fastq.gz
  out=raw/mouse_2_Cd4Cre_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/023/SRR16943423/SRR16943423_2.fastq.gz
  out=raw/mouse_2_Cd4Cre_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/027/SRR16943427/SRR16943427_1.fastq.gz
  out=raw/mouse_2_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/027/SRR16943427/SRR16943427_2.fastq.gz
  out=raw/mouse_2_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/024/SRR16943424/SRR16943424_1.fastq.gz
  out=raw/mouse_1_Cd4Cre_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/024/SRR16943424/SRR16943424_2.fastq.gz
  out=raw/mouse_1_Cd4Cre_R2.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/026/SRR16943426/SRR16943426_1.fastq.gz
  out=raw/mouse_3_R1.fastq.gz
ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/026/SRR16943426/SRR16943426_2.fastq.gz
  out=raw/mouse_3_R2.fastq.gz

One command Solution

The data was obtained using NEBNext Immune Sequencing Kit for BCR repertoire. The easiest way to perform upstream analysis for this data would be to use a dedicated mixcr preset neb-mouse-rna-xcr-umi-nebnext with mixcr analyze command. This preset was spesifically designed for this kit and includes UMI correction, primer sequences trimming and assembles clonotypes by VDJRegion.

The exact command for a single sample you can see bellow:

mixcr analyze neb-mouse-rna-xcr-umi-nebnext \
    raw/mouse_3_Cd4Cre_R1.fastq.gz \
    raw/mouse_3_Cd4Cre_R2.fastq.gz \
    results/mouse_3_Cd4Cre_R1

The command above will generate the following output files:

> ls results/

# human-readable reports for every step of the pipeline in txt and json formats
mouse_3_Cd4Cre.align.report.txt
mouse_3_Cd4Cre.align.report.json
mouse_3_Cd4Cre.refine.report.txt
mouse_3_Cd4Cre.refine.report.json
mouse_3_Cd4Cre.assemble.report.txt
mouse_3_Cd4Cre.assemble.report.json

# raw alignments (highly compressed binary file)
mouse_3_Cd4Cre.vdjca

# alignments with corrected UMI barcode sequences 
mouse_3_Cd4Cre.refined.vdjca

# IG clonotypes (highly compressed binary file)
mouse_3_Cd4Cre.clns

# IG clonotypes exported in tab-delimited tsv
mouse_3_Cd4Cre.clones_IGH.tsv
mouse_3_Cd4Cre.clones_IGK.tsv 
mouse_3_Cd4Cre.clones_IGL.tsv

Clonotype tables is the main result of the upstream analysis. They are stored in a highly compressed and efficient binary .clns file and can be exported in many ways: detailed tab-delimited format with dozens of customizable columns, human-readable for manual inspection, and AIRR format suitable for many scientific downstream analysis tools. .clns files can be also used for downstream analysis using mixcr postanalisis.

By default, MiXCR exports clonotypes in a tab-delimited format separately for each immunological chain.

See first 500 records from mouse_3_Cd4Cre.clones_IGH clonotype table
cloneId readCount readFraction uniqueUMICount uniqueUMIFraction targetSequences targetQualities allVHitsWithScore allDHitsWithScore allJHitsWithScore allCHitsWithScore allVAlignments allDAlignments allJAlignments allCAlignments nSeqFR1 minQualFR1 nSeqCDR1 minQualCDR1 nSeqFR2 minQualFR2 nSeqCDR2 minQualCDR2 nSeqFR3 minQualFR3 nSeqCDR3 minQualCDR3 nSeqFR4 minQualFR4 aaSeqFR1 aaSeqCDR1 aaSeqFR2 aaSeqCDR2 aaSeqFR3 aaSeqCDR3 aaSeqFR4 refPoints
0 41019 0.154971 3816 0.127234 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCCTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATTAGGAAGACTGGGCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2865.4) IGHD4-100(25),IGHD6-200(25) IGHJ1*00(538) IGHA*00(308) 0|295|314|0|295|ST71C|2921.0 14|19|33|302|307||25.0;16|21|87|300|305||25.0 19|73|73|307|361||540.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCCTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATTAGGAAGACTGGGCTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARLGRLGYWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:1:295:302:-3:-3:307:307:1:330:361::
1 32821 0.123999 2819 0.0939917 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGTAAGGCCACACTGACTGTAGACAAACCCTCCAGTACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2829),IGHV1-62-300(2771.2) IGHD4-1*00(45) IGHJ4*00(498.1) IGHA*00(307.8) 0|294|314|0|294|SC197TSC230T|2882.0;0|294|314|0|294|SA63TSC197TSC230TSC284T|2824.0 14|23|33|300|309||45.0 24|74|74|311|361||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGTAAGGCCACACTGACTGTAGACAAACCCTCCAGTACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGTGTLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:300:-3:1:309:311:-4:330:361::
5 13919 0.0525864 1230 0.0410109 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAACACAATGAGAAGTTGAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGACGCCCAGTTGGAGGTTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2807.8),IGHV1-62-300(2745.9) IGHD4-1*00(35) IGHJ2*00(488.5) IGHA*00(307.7) 0|294|314|0|294|SG176AST177CSC191G|2853.0;0|294|314|0|294|SA63TSG176AST177CSC191GSC284T|2795.0 2|9|33|296|303||35.0 19|68|68|309|358||490.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAACACAATGAGAAGTTGAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGACGCCCAGTTGGAGGTTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KHNEKLKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRPVGGYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:296:9:-13:303:309:1:327:358::
6 13382 0.0505576 1286 0.0428781 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAACTACTGGATACACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAACACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAAGACTCTGCGGTCTATTATTGTTCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2719.7),IGHV1-62-300(2655.9) IGHD4-1*00(45) IGHJ4*00(498.5) IGHA*00(307.9) 0|294|314|0|294|SC30TSG91ASG101ASG229ASG266ASG288T|2766.0;0|294|314|0|294|SC30TSA63TSG91ASG101ASG229ASG266ASC284TSG288T|2708.0 14|23|33|300|309||45.0 24|74|74|311|361||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAACTACTGG 45 ATACACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAACACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAAGACTCTGCGGTCTATTAT 45 TGTTCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAEFVKPGASVKLSCKAS GYTFTNYW IHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSNTAYMQLSSLTSEDSAVYY CSRRGTGTLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:300:-3:1:309:311:-4:330:361::
9 10719 0.0404967 1556 0.0518805 GAGGTTCAGCTCCAGCAGTCTGGGACTGTGCTGGCAAGGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGACTTCTGGCTACACATTTACCAGCTACTGGATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATAGGGGCTATTTATCCTGGAAATAGTGATACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTACTGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-5*00(2921.1) IGHD3-2*00(60) IGHJ3*00(478.2) IGHG2C*00(65.3) 0|294|314|0|294||2940.0 19|31|48|295|307||60.0 20|68|68|307|355||480.0 nan GAGGTTCAGCTCCAGCAGTCTGGGACTGTGCTGGCAAGGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGACTTCT 45 GGCTACACATTTACCAGCTACTGG 45 ATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATAGGGGCT 45 ATTTATCCTGGAAATAGTGATACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTAC 45 TGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGTVLARPGASVKMSCKTS GYTFTSYW MHWVKQRPGQGLEWIGA IYPGNSDT SYNQKFKGKAKLTAVTSASTAYMELSSLTNEDSAVYY CTRPAQATWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:295:-3👎307:307:0:324:355::
11 9725 0.0367414 941 0.031375 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCTCATTACGACGGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2841) IGHD2-400(45),IGHD2-700(40) IGHJ2*00(469.3) IGHA*00(307.8) 0|290|314|0|290||2900.0 26|35|51|292|301||45.0;27|35|51|293|301||40.0 21|68|68|302|349||470.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 ACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCTCATTACGACGGCTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSGVP TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CAHYDGYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:292:-9:1:301:302:-1:318:349::
13 8452 0.0319319 1304 0.0434783 GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGAGGATGGTGAAACTAAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGGGACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-2*00(2915.1) nan IGHJ2*00(478) nan 0|293|314|0|293||2930.0 nan 20|68|68|295|343||480.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAGACTACTAT 45 ATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGAGGATGGTGAAACT 45 AAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTGCTAGGGACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGAELVKPGASVKLSCTAS GFNIKDYY MHWVKQRTEQGLEWIGR IDPEDGET KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CARDYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285👎293:::::295:0:312:343::
15 7195 0.0271829 1282 0.0427447 GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCAGGGTTCACTTTTAGTGGCTTCTGGATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGACATTAATTCTGATGGCAGTGCAATAAACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTCTGTATGAGATATGGTAACTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV11-2*00(2951.3) nan IGHJ1*00(539.3) nan 0|297|316|0|297||2970.0 nan 16|73|73|298|355|SG19A|541.0 nan GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCA 45 GGGTTCACTTTTAGTGGCTTCTGG 45 ATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGAC 45 ATTAATTCTGATGGCAGTGCAATA 45 AACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTC 45 TGTATGAGATATGGTAACTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLLETGGGLVQPGGSRGLSCEGS GFTFSGFW MSWVRQTPGKTLEWIGD INSDGSAI NYAPSIKDRFTIFRDNDKSTLYLQMSNVRSEDTATYF CMRYGNYWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:1:297:::::298:4:324:355::
16 6562 0.0247915 624 0.0208055 CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAAATATTAATCCTAGCAATGGTGGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGATTTTATTACTACGGTAGTAGCCTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-53*00(2911.3) IGHD1-1*00(85) IGHJ2*00(418.2) IGHA*00(307.5) 0|298|314|0|298|SC295T|2951.0 26|43|69|298|315||85.0 26|68|68|316|358||420.0 nan CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAAAT 45 ATTAATCCTAGCAATGGTGGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGATTTTATTACTACGGTAGTAGCCTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGTELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGN INPSNGGT NYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYY CARFYYYGSSLDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:4:298:298:-3:-3:315:316:-6:327:358::
19 4843 0.018297 622 0.0207389 CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCTGGCTACGCATTCAGTAACTCCTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGGATTTATCCTGGAGATGGAGATACTAACTACAATGGGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTACTTCTGTGCAAGACGATGGTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-82*00(2892.8) IGHD2-3*00(25) IGHJ2*00(428.6) IGHG2C*00(64.2) 0|294|314|0|294|SG91A|2911.0 22|27|51|295|300||25.0 25|68|68|300|343||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCT 45 GGCTACGCATTCAGTAACTCCTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGG 45 ATTTATCCTGGAGATGGAGATACT 45 AACTACAATGGGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTACTTC 45 TGTGCAAGACGATGGTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYAFSNSW MNWVKQRPGKGLEWIGR IYPGDGDT NYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CARRWFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:295:-5:-7:300:300:-5:312:343::
20 4688 0.0177114 418 0.013937 CAGATCCAGTTGGTACAGTCTGGACCTGAGGTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATGAACACCTACTCTGGAGTGCCAACATATACTGATGACTTCAGGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGACGGGGTACTACGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2705.6) IGHD1-1*00(75) IGHJ4*00(518.2) IGHA*00(307.6) 0|294|314|0|294|SC30GSA152GSG180ASA193G|2824.0 28|43|69|299|314||75.0 22|74|74|321|373||520.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGGTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATGAACACCTACTCTGGAGTGCCA 45 ACATATACTGATGACTTCAGGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCAAGACGGGGTACTACGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QIQLVQSGPEVKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW MNTYSGVP TYTDDFRGRFAFSLETSASTAYLQINNLKNEDTATYF CARRGTTVVAARYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-5:-3:314:321:-2:342:373::
23 4336 0.0163816 582 0.0194052 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTATTGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2851.4) IGHD4-1*00(35) IGHJ2*00(499.4) nan 0|298|321|0|298|SC253GSC274TSC287TSC292T|2864.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTAT 45 TGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKISSVDTADIATYY CVRTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
24 4333 0.0163702 728 0.0242731 GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCAGGGTTCACTTTTAGTGGCTTCTGGATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGACATTAATTCTGATGGCAGTGCAATAAACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTCTGTATGAGGGGAACTGGCTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV11-2*00(2911.4) IGHD4-1*00(30) IGHJ1*00(498.7) nan 0|293|316|0|293||2930.0 13|19|33|296|302||30.0 23|73|73|302|352||500.0 nan GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCA 45 GGGTTCACTTTTAGTGGCTTCTGG 45 ATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGAC 45 ATTAATTCTGATGGCAGTGCAATA 45 AACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTC 45 TGTATGAGGGGAACTGGCTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLLETGGGLVQPGGSRGLSCEGS GFTFSGFW MSWVRQTPGKTLEWIGD INSDGSAI NYAPSIKDRFTIFRDNDKSTLYLQMSNVRSEDTATYF CMRGTGWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:-3:293:296:-2:-3:302:302:-3:321:352::
26 4173 0.0157657 419 0.0139704 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAATTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAATGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGCGGACTCTGCTGTCTATTTCTGTGCAAGAAACTACGGTAACTCGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2767.2) IGHD2-800(46),IGHD1-100(45) IGHJ3*00(499.5) IGHA*00(307.8) 0|294|314|0|294|SC104TSG163ASG213ASA265C|2824.0 20|32|51|295|307|ST24C|46.0;29|38|69|295|304||45.0 18|68|68|308|358||500.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAATTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAATGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGCGGACTCTGCTGTCTATTTC 45 TGTGCAAGAAACTACGGTAACTCGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGNGNT YYNEKFKGKATLTTEKSSSTAYMQLSSLTSADSAVYF CARNYGNSAWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:295:-3:-2:307:308:2:327:358::
29 3836 0.0144925 473 0.0157709 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCGGCGAGGAGGGGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2881.7) nan IGHJ2*00(398.7) IGHG2C*00(63.9) 0|290|314|0|290||2900.0 nan 28|68|68|303|343||400.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCGGCGAGGAGGGGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CAARRGDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:::::303:-8:312:343::
31 3616 0.0136614 356 0.0118698 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACGTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAACTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGAGGAGGCTACGAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2836) IGHD3-200(40),IGHD3-100(35),IGHD5-7*00(35) IGHJ2*00(478.6) IGHA*00(307.3) 0|294|314|0|294|SC83GSG245A|2882.0 25|33|48|298|306||40.0;28|35|51|299|306||35.0;15|22|87|297|304||35.0 20|68|68|307|355||480.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACGTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAACTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGAGGAGGCTACGAACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CAREEATNYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:298:-9:1:306:307:0:324:355::
32 3387 0.0127962 606 0.0202054 GAAGTGAAGCTTGAGGAGTCTGGAGGAGGCTTGGTGCAACCTGGAGGATCCATGAAACTCTCCTGTGTTGCCTCTGGATTCACTTTCAGTAACTACTGGATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTCAAATTAGATTGAAATCTGATAATTATGCAACACATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGGGCTGAAGACACTGGAATTTATTACTGCACATACTACGGTAGTAGTTCCCTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV6-3*00(2943.1) IGHD1-1*00(70) IGHJ3*00(417.3) nan 0|297|319|0|297||2970.0 28|42|69|297|311||70.0 26|68|68|316|358||420.0 nan GAAGTGAAGCTTGAGGAGTCTGGAGGAGGCTTGGTGCAACCTGGAGGATCCATGAAACTCTCCTGTGTTGCCTCT 45 GGATTCACTTTCAGTAACTACTGG 45 ATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTCAA 45 ATTAGATTGAAATCTGATAATTATGCAACA 45 CATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGGGCTGAAGACACTGGAATTTATTAC 45 TGCACATACTACGGTAGTAGTTCCCTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVKLEESGGGLVQPGGSMKLSCVAS GFTFSNYW MNWVRQSPEKGLEWVAQ IRLKSDNYAT HYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYY CTYYGSSSLAYW GQGTLVTVSA_ ::::0:75:99:150:180:291:-2:297:297:-5:-4:311:316:-6:327:358::
33 3317 0.0125317 311 0.0103694 CAGGTCCAGCTGAAGCAGTCTGGAGCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACACCTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGCCTTGAGTGGATTGGAAAGATTGGTCCTGGAAGTGGTAGTACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTTCTGTGCAAGATCGAAGGCGTACTACTTTGACTGCTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-77*00(2919.4) nan IGHJ2*00(470.5) IGHA*00(308.1) 0|296|314|0|296||2960.0 nan 18|68|68|302|352|SA32G|471.0 nan CAGGTCCAGCTGAAGCAGTCTGGAGCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACACCTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGCCTTGAGTGGATTGGAAAG 45 ATTGGTCCTGGAAGTGGTAGTACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTTC 45 TGTGCAAGATCGAAGGCGTACTACTTTGACTGCTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLKQSGAELVKPGASVKISCKAS GYTFTDYY INWVKQRPGQGLEWIGK IGPGSGST YYNEKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CARSKAYYFDCW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:::::302:2:321:352::
34 3231 0.0122068 410 0.0136703 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2966.6) IGHD4-1*00(35) IGHJ2*00(498.7) nan 0|298|321|0|298||2980.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
35 3078 0.0116288 423 0.0141038 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGGAAGATCGGTAACTACGGATATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2943.5) IGHD2-800(50),IGHD2-500(45),IGHD2-6*00(45) IGHJ4*00(558.8) IGHG2C*00(64.8) 0|296|321|0|296||2960.0 25|35|51|303|313||50.0;26|35|51|304|313||45.0;26|35|51|304|313||45.0 18|74|74|314|370||560.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGGAAGATCGGTAACTACGGATATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARKIGNYGYYYAMDYW GQGTSVTVSS_ ::::0:75:105:156:177:288:-5:296:303:-8:1:313:314:2:339:370::
36 3066 0.0115834 420 0.0140037 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGGATTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAATGGATTGGTAACATTTACCCTTCTGATAGTGAAACTCACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAACTGGGACGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-61*00(2905.2) IGHD4-1*00(40) IGHJ2*00(458.1) nan 0|292|314|0|292||2920.0 15|23|33|292|300||40.0 22|68|68|300|346||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGGATTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAATGGATTGGTAAC 45 ATTTACCCTTCTGATAGTGAAACT 45 CACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAACTGGGACGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVRPGSSVKLSCKAS GYTFTSYW MDWVKQRPGQGLEWIGN IYPSDSET HYNQKFKDKATLTVDKSSSTAYMQLSSLTSEDSAVYY CATGTYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-2:292:292:-4:1:300:300:-2:315:346::
38 2997 0.0113228 384 0.0128034 CAGATCCAGTTCGTGCAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGTGTATACCTTCACAGAATATCCAATGCACTGGGTGAAGCAGGCTCCAGGAAAGGGTTTCAAGTGGATGGGCTGGATAAACACCTACTCTGGAGAGCCAACATATGCTGACGACTTCAAGGGACGGTTTGCCTTTTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGATTGGGCTACGGTAGTAGCTGGGGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-2*00(2921.1) IGHD3-100(40),IGHD1-100(35),IGHD3-2*00(35) IGHJ1*00(491.6) IGHG2C*00(64.9) 0|295|314|0|295||2950.0 27|35|51|296|304||40.0;30|37|69|299|306||35.0;26|33|48|297|304||35.0 15|73|73|306|364|SA22GSC23GST24G|493.0 nan CAGATCCAGTTCGTGCAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GTGTATACCTTCACAGAATATCCA 45 ATGCACTGGGTGAAGCAGGCTCCAGGAAAGGGTTTCAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGAGCCA 45 ACATATGCTGACGACTTCAAGGGACGGTTTGCCTTTTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCAAGATTGGGCTACGGTAGTAGCTGGGGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QIQFVQSGPELKKPGETVKISCKAS VYTFTEYP MHWVKQAPGKGFKWMGW INTYSGEP TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CARLGYGSSWGYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:1:295:296:-10:1:304:306:5:333:364::
39 2683 0.0101365 268 0.00893572 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGTTGTCCTGCAAGGCTTCTGGCAACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGAAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATTGGTTCTGGGGTACTTTGACTATTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2818.8) IGHD5-700(26),IGHD5-800(26),IGHD6-2*00(26) IGHJ2*00(429.8) IGHA*00(307.3) 0|295|314|0|295|SC57TST78ASC114A|2863.0 0|8|87|296|304|SG4C|26.0;0|8|87|296|304|SG4C|26.0;0|8|87|296|304|SG4C|26.0 22|68|68|306|352|SC33T|431.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGTTGTCCTGCAAGGCTTCT 45 GGCAACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGAAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATTGGTTCTGGGGTACTTTGACTATTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GNTFTSYG ISWVKKRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARLVLGYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:296:29:-50:304:306:-2:321:352::
40 2673 0.0100987 384 0.0128034 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2924.9) IGHD1-1*00(85) IGHJ1*00(508.4) nan 0|294|321|0|294||2940.0 23|40|69|294|311||85.0 22|73|73|313|364||510.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CAFITTVVDWYFDVW GTGTTVTVSS_ ::::0:75:105:156:177:288:-7:294:294:0:-6:311:313:-2:333:364::
42 2606 0.00984555 230 0.00766871 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCATGGCTTCTGGCTACACTTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGATCAGGCGGTAGTAGCCGCCAGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2869.9) IGHD1-1*00(50) IGHJ3*00(529.2) IGHA*00(308.1) 0|296|314|0|296|SA67T|2931.0 33|43|69|299|309||50.0 15|68|68|311|364||530.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCATGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTC 45 TGTGCAAGATCAGGCGGTAGTAGCCGCCAGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLKQSGAELVRPGASVKLSCMAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGSGNT YYNEKFKGKATLTAEKSSSTAYMQLSSLTSEDSAVYF CARSGGSSRQAWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:2:296:299:-10:-3:309:311:5:333:364::
44 2574 0.00972466 334 0.0111363 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2936.4) IGHD2-800(60),IGHD2-700(55) IGHJ2*00(449.7) IGHG2C*00(65.1) 0|296|314|0|296||2960.0 17|29|51|298|310||60.0;17|28|51|298|309||55.0 20|68|68|310|358|ST25G|451.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTC 45 TGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGSGNT YYNEKFKGKATLTAEKSSSTAYMQLSSLTSEDSAVYF CARSVYYGNYVDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:298:0:-5:310:310:0:327:358::
45 2449 0.0092524 275 0.00916911 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAGCCTATGGAATGAGCTGGATGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACATATGCTGATGACTTCATGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCATCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTACAAGACGGGGTACTACGGTGGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2674.5) IGHD1-1*00(61) IGHJ4*00(518.3) IGHA*00(307.3) 0|294|314|0|294|SA90GSG108ASA193TSG229TSG288A|2795.0 28|43|69|299|314|SA37G|61.0 22|74|74|321|373||520.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAGCCTATGGA 45 ATGAGCTGGATGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 ACATATGCTGATGACTTCATGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCATCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTACAAGACGGGGTACTACGGTGGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTAYG MSWMKQAPGKGLKWMGW INTYSGVP TYADDFMGRFAFSLETSAITAYLQINNLKNEDTATYF CTRRGTTVVAARYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-5:-3:314:321:-2:342:373::
46 2440 0.0092184 324 0.0108029 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTTTGGTATGGGTGTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACACATTTGGTGGGATGATGATAAGTACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-8*00(2972.3) IGHD2-4*00(70) IGHJ3*00(498.5) IGHG2C*00(64.9) 0|299|321|0|299||2990.0 20|34|51|301|315||70.0 18|68|68|317|367||500.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTTTGGTATGGGT 45 GTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTGGTGGGATGATGATAAG 45 TACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVTLKESGPGILQPSQTLSLTCSFS GFSLSTFGMG VGWIRQPSGKGLEWLAH IWWDDDK YYNPALKSRLTISKDTSKNQVFLKIANVDTADTATYY CARMDYDYDRAWFAYW GQGTLVTVSA_ ::::0:75:105:156:177:288:-2:299:301:-3:0:315:317:2:336:367::
47 2412 0.00911262 227 0.00756868 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACGACTTCCCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2893.7) IGHD5-5*00(26) IGHJ4*00(498.3) IGHA*00(308.1) 0|294|314|0|294||2940.0 9|17|30|294|302|SA14T|26.0 24|74|74|302|352||500.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACGACTTCCCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARRLPYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:294:1:-3:302:302:-4:321:352::
48 2362 0.00892371 226 0.00753534 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2890.5),IGHV1-62-300(2832.8) IGHD2-8*00(50) IGHJ4*00(497.7) IGHA*00(303.1) 0|294|314|0|294||2940.0;0|294|314|0|294|SA63TSC284T|2882.0 21|31|51|299|309||50.0 24|74|74|311|361||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGYGNLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-4:-3:309:311:-4:330:361::
49 2351 0.00888216 360 0.0120032 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2938.7) IGHD2-800(60),IGHD2-700(55) IGHJ2*00(449.6) IGHG2B*00(55.9) 0|296|314|0|296||2960.0 17|29|51|298|310||60.0;17|28|51|298|309||55.0 20|68|68|310|358|ST25G|451.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTC 45 TGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGSGNT YYNEKFKGKATLTAEKSSSTAYMQLSSLTSEDSAVYF CARSVYYGNYVDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:298:0:-5:310:310:0:327:358::
51 2281 0.00861769 225 0.007502 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGTAAGAGAGGAGGCTACGAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2866.1) IGHD3-200(40),IGHD3-100(35),IGHD5-7*00(35) IGHJ2*00(476.7) IGHA*00(307.4) 0|294|314|0|294|SC289T|2911.0 25|33|48|298|306||40.0;28|35|51|299|306||35.0;15|22|87|297|304||35.0 20|68|68|307|355||480.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGTAAGAGAGGAGGCTACGAACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CVREEATNYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:298:-9:1:306:307:0:324:355::
52 2270 0.00857613 221 0.00736863 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTAAAGCCTGGGGCTTCAGTGAAGTTGTCCTGCAAGGCTTCTGGCTACACTTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAATGATTCATCCTAATAGTGGTAGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATCCTATGGTTACGACCCTCTCTTTGGCTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-64*00(2906.5) IGHD2-7*00(65) IGHJ2*00(409.5) IGHA*00(307.4) 0|296|314|0|296||2960.0 21|34|51|296|309||65.0 24|68|68|314|358|SA29G|411.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTAAAGCCTGGGGCTTCAGTGAAGTTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAATG 45 ATTCATCCTAATAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATCCTATGGTTACGACCCTCTCTTTGGCTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGM IHPNSGST NYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYY CARSYGYDPLFGYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:296:-4:0:309:314:-4:327:358::
54 2209 0.00834567 320 0.0106695 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACCGATCTACTATGATTACGACGTGGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2921.1) IGHD2-400(105),IGHD2-700(91) IGHJ2*00(418.5) IGHG2C*00(65.1) 0|294|314|0|294||2940.0 15|36|51|296|317||105.0;15|36|51|296|317|SG26A|91.0 26|68|68|319|361||420.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACCGATCTACTATGATTACGACGTGGTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARPIYYDYDVVDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:296:2:2:317:319:-6:330:361::
57 2106 0.00795654 314 0.0104695 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTAAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGTGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCCCCTATTACTACGGCGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-59*00(2881.6) IGHD1-1*00(55) IGHJ2*00(458.2) nan 0|290|314|0|290||2900.0 25|36|69|293|304||55.0 22|68|68|306|352||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTAAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGTG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCCCCTATTACTACGGCGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVRPGTSVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGV IDPSDSYT NYNQKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYY CAPITTAYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:293:-2:-10:304:306:-2:321:352::
59 2042 0.00771474 269 0.00896906 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACTTTCACTGTCTACTGGATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAGATTTTACCTGGAAGTGGTAGTACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACCTTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAATCCCTGGAGGGTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(2819.3) nan IGHJ2*00(368.3) IGHG2C*00(64.3) 0|292|314|0|292|SA83TSG91TSA206C|2833.0 nan 31|68|68|303|340||370.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 GGCTACACTTTCACTGTCTACTGG 45 ATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAG 45 ATTTTACCTGGAAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGGGCAAGGCCACCTTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTAC 45 TGTGCAATCCCTGGAGGGTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT GYTFTVYW IEWVKQRPGHGLEWIGE ILPGSGST NYNEKFKGKATFTADTSSNTAYMQLSSLTTEDSAIYY CAIPGGYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-2:292:::::303:-11:309:340::
61 2004 0.00757118 217 0.00723526 GAGGTTCAGCTGCAGCAGTCTGTGGCAGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAAACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATCCTAAATATGCCCCGAAGTTCCAGGGCAAGGCCACTATAACTGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCATCTATTACTGTGCTAGACAGCTCAGGCTACCTACGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-3*00(2864.5) IGHD3-2*00(66) IGHJ2*00(499.2) IGHA*00(308.1) 0|294|314|0|294|SA171C|2911.0 19|35|48|294|310|SG32C|66.0 18|68|68|311|361||500.0 nan GAGGTTCAGCTGCAGCAGTCTGTGGCAGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAAACACCTAT 45 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGCGAATGGTAATCCT 45 AAATATGCCCCGAAGTTCCAGGGCAAGGCCACTATAACTGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCATCTATTAC 45 TGTGCTAGACAGCTCAGGCTACCTACGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSVAELVRPGASVKLSCTAS GFNIKNTY MHWVKQRPEQGLEWIGR IDPANGNP KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAIYY CARQLRLPTYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:294:-3:3:310:311:2:330:361::
65 1740 0.00657378 153 0.00510136 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACTCTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2861.9),IGHV1-62-300(2803.9) IGHD2-8*00(50) IGHJ4*00(496.7) IGHA*00(307.3) 0|294|314|0|294|SA206T|2911.0;0|294|314|0|294|SA63TSA206TSC284T|2853.0 21|31|51|299|309||50.0 24|74|74|311|361||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACTCTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGYGNLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-4:-3:309:311:-4:330:361::
66 1711 0.00646421 187 0.006235 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAACAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTATTATAATGAGAAGTTCAGGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAAGGGAAAACTACGGTAGTAGCTACAGTGTGTCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2773.6) IGHD1-1*00(85) IGHJ3*00(389.6) IGHA*00(308) 0|294|314|0|294|SG113ASC176TSC179TSA193G|2824.0 29|46|69|301|318||85.0 29|68|68|325|364||390.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAACAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TATTATAATGAGAAGTTCAGGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAAGGGAAAACTACGGTAGTAGCTACAGTGTGTCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFRGKATLTADKSSSTAYMELRSLTSEDSAVYF CARRENYGSSYSVSYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:301:-6:0:318:325:-9:333:364::
67 1589 0.00600329 153 0.00510136 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACGTATGCTGATGACTTCAAGGGACGGTTTACCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAAGACACGGCTACATATTTCTGTGCAAGACGGGGTACTGCGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2736.6) IGHD1-1*00(61) IGHJ4*00(518.5) IGHA*00(307.7) 0|294|314|0|294|SA176GSG204ASG266A|2853.0 28|43|69|299|314|SA32G|61.0 22|74|74|321|373||520.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 ACGTATGCTGATGACTTCAAGGGACGGTTTACCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAAGACACGGCTACATATTTC 45 TGTGCAAGACGGGGTACTGCGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSGVP TYADDFKGRFTFSLETSASTAYLQINNLKNEDTATYF CARRGTAVVAARYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-5:-3:314:321:-2:342:373::
73 1448 0.00547059 194 0.00646839 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2922.5),IGHV1-62-300(2864.6) IGHD2-8*00(50) IGHJ4*00(497.1) IGHG2C*00(64.8) 0|294|314|0|294||2940.0;0|294|314|0|294|SA63TSC284T|2882.0 21|31|51|299|309||50.0 24|74|74|311|361||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGYGNLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-4:-3:309:311:-4:330:361::
74 1410 0.00532703 135 0.0045012 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAAGGGAAAACTACGGTAGTAGCTACAGTGTGTCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2885.9) IGHD1-1*00(85) IGHJ3*00(389.5) IGHA*00(307.6) 0|294|314|0|294||2940.0 29|46|69|301|318||85.0 29|68|68|325|364||390.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAAGGGAAAACTACGGTAGTAGCTACAGTGTGTCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARRENYGSSYSVSYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:301:-6:0:318:325:-9:333:364::
78 1323 0.00499834 121 0.00403441 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAGCAGGCTCCAGGACAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGACGGGGTACTACAGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2770.6) IGHD1-1*00(61) IGHJ4*00(518.7) IGHA*00(307.9) 0|294|314|0|294|SA113GSA126C|2882.0 28|43|69|299|314|SG34A|61.0 22|74|74|321|373||520.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAGCAGGCTCCAGGACAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 ACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCAAGACGGGGTACTACAGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGQGLKWMGW INTYSGVP TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CARRGTTVVAARYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-5:-3:314:321:-2:342:373::
82 1158 0.00437496 163 0.00543478 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTTTGGTATGGGTGTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACACATTTGGTGGGATGATGATAAGTACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATAGAGGGTAATGGCGGTTACTATTCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-8*00(2990) IGHD1-100(25),IGHD2-400(25),IGHD2-8*00(25) IGHJ4*00(499.8) IGHG2C*00(64.8) 0|301|321|0|301||3010.0 15|20|69|304|309||25.0;3|8|51|304|309||25.0;25|30|51|303|308||25.0 21|74|74|314|367|SG28T|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTTTGGTATGGGT 45 GTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTGGTGGGATGATGATAAG 45 TACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAATAGAGGGTAATGGCGGTTACTATTCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVTLKESGPGILQPSQTLSLTCSFS GFSLSTFGMG VGWIRQPSGKGLEWLAH IWWDDDK YYNPALKSRLTISKDTSKNQVFLKIANVDTADTATYY CARIEGNGGYYSMDYW GQGTSVTVSS_ ::::0:75:105:156:177:288:0:301:304:8:-26:309:314:-1:336:367::
83 1135 0.00428807 104 0.00346759 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGACGGGGTACTACGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2819.9) IGHD1-1*00(75) IGHJ4*00(518.4) IGHA*00(307.8) 0|294|314|0|294||2940.0 28|43|69|299|314||75.0 22|74|74|321|373||520.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 ACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCAAGACGGGGTACTACGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSGVP TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CARRGTTVVAARYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-5:-3:314:321:-2:342:373::
85 1111 0.00419739 148 0.00493465 CAGGTCCAATTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2858.2),IGHV1-62-300(2800.3) IGHD2-8*00(50) IGHJ4*00(497.4) IGHG2C*00(63.9) 0|294|314|0|294|SC9TSC30T|2882.0;0|294|314|0|294|SC9TSC30TSA63TSC284T|2824.0 21|31|51|299|309||50.0 24|74|74|311|361||500.0 nan CAGGTCCAATTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAEFVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGYGNLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-4:-3:309:311:-4:330:361::
88 1029 0.0038876 172 0.00573486 GAGGTGAAGCTGGTGGAGTCTGGAGGAGGCTTGGTACAGCCTGGGGGTTCTCTGAGTCTCTCCTGTGCAGCTTCTGGATTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGGAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAATGCCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGATCCCCCTATAGTAACTACCTCCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV7-3*00(2971.3) IGHD2-500(65),IGHD2-600(65) IGHJ1*00(509) IGHG2C*00(66.6) 0|301|324|0|301||3010.0 21|34|51|305|318||65.0;21|34|51|305|318||65.0 22|73|73|322|373||510.0 nan GAGGTGAAGCTGGTGGAGTCTGGAGGAGGCTTGGTACAGCCTGGGGGTTCTCTGAGTCTCTCCTGTGCAGCTTCT 45 GGATTCACCTTCACTGATTACTAC 45 ATGAGCTGGGTCCGCCAGCCTCCAGGGAAGGCACTTGAGTGGTTGGGTTTT 45 ATTAGAAACAAAGCTAATGGTTACACAACA 45 GAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAATGCCCTGAGAGCTGAGGACAGTGCCACTTATTAC 45 TGTGCAAGATCCCCCTATAGTAACTACCTCCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVKLVESGGGLVQPGGSLSLSCAAS GFTFTDYY MSWVRQPPGKALEWLGF IRNKANGYTT EYSASVKGRFTISRDNSQSILYLQMNALRAEDSATYY CARSPYSNYLHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:180:291:-3:301:305:-4:0:318:322:-2:342:373::
90 980 0.00370247 173 0.0057682 GAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTTAACATTAAAGACGACTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGGATTGATCCTGAGAATGGTGATACTGAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTACTACCTTAATTTATTACTACGGTAGTAGCCATGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-4*00(2911.2) IGHD1-1*00(110) IGHJ2*00(408.4) IGHG2C*00(66.2) 0|293|314|0|293||2930.0 21|43|69|296|318||110.0 27|68|68|320|361||410.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTTAACATTAAAGACGACTAT 45 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGG 45 ATTGATCCTGAGAATGGTGATACT 45 GAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTACTACCTTAATTTATTACTACGGTAGTAGCCATGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGAELVRPGASVKLSCTAS GFNIKDDY MHWVKQRPEQGLEWIGW IDPENGDT EYASKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CTTLIYYYGSSHDYW GQGTTLTVSS_ ::::0:75:99:150:174:285👎293:296:2:-3:318:320:-7:330:361::
91 973 0.00367603 140 0.00466791 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATAACCTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGATATTTATCCTGGTAGTGGTAGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATCCTCACTACTAGGAGGCCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-55*00(2942) IGHD2-400(31),IGHD1-100(30),IGHD2-8*00(30) IGHJ1*00(510.1) nan 0|296|314|0|296||2960.0 18|27|51|300|309|ST24G|31.0;4|10|69|300|306||30.0;18|24|51|300|306||30.0 19|73|73|310|364|ST21C|511.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATAACCTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAT 45 ATTTATCCTGGTAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATCCTCACTACTAGGAGGCCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKMSCKAS GYTFTSYW ITWVKQRPGQGLEWIGD IYPGSGST NYNEKFKSKATLTVDTSSSTAYMQLSSLTSEDSAVYY CARSSLLGGHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:2:296:300:-1:-7:309:310:1:333:364::
94 867 0.00327555 84 0.00280075 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAACTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTTCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2805),IGHV1-62-300(2747.2) IGHD4-1*00(45) IGHJ4*00(498.2) IGHA*00(308) 0|294|314|0|294|SC30TSG91ASG288T|2853.0;0|294|314|0|294|SC30TSA63TSG91ASC284TSG288T|2795.0 14|23|33|300|309||45.0 24|74|74|311|361||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAACTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTTCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAEFVKPGASVKLSCKAS GYTFTNYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CSRRGTGTLYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:300:-3:1:309:311:-4:330:361::
97 848 0.00320377 124 0.00413444 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCCCTTATTACTACGGCACCCCCGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-69*00(2879.5) IGHD1-1*00(60) IGHJ3*00(437.2) nan 0|290|314|0|290||2900.0 24|36|69|292|304||60.0 24|68|68|311|355||440.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCCCTTATTACTACGGCACCCCCGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQPGAELVMPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGE IDPSDSYT NYNQKFKGKSTLTVDKSSSTAYMQLSSLTSEDSAVYY CALITTAPPFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:-4:290:292:-1:-10:304:311:-4:324:355::
99 839 0.00316977 121 0.00403441 CAGGTCCAGCTACAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACACCTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGGATTTTTCCTGGAAGTGGTAGTACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTTACTGTAGACAAATCCTCCAGCACAGCCTACATGTTGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTCTGTGCAACTACGGTAGTAGCTACGAGGGACTACTTCTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-75*00(2896.3) IGHD1-1*00(85) IGHJ1*00(499.4) nan 0|292|314|0|292||2920.0 30|47|69|292|309||85.0 20|73|73|317|370|SA22T|501.0 nan CAGGTCCAGCTACAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACACCTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGG 45 ATTTTTCCTGGAAGTGGTAGTACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTTACTGTAGACAAATCCTCCAGCACAGCCTACATGTTGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAACTACGGTAGTAGCTACGAGGGACTACTTCTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYTFTDYY INWVKQRPGQGLEWIGW IFPGSGST YYNEKFKGKATLTVDKSSSTAYMLLSSLTSEDSAVYF CATTVVATRDYFWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:-2:292:292:-7:1:309:317:0:339:370::
101 799 0.00301865 111 0.00370099 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAGGAGCCTACTATAGTCTTTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2975.6) IGHD2-500(50),IGHD2-600(50) IGHJ4*00(528.1) IGHG2C*00(65.3) 0|302|321|0|302|SA297G|2991.0 18|28|51|302|312||50.0;18|28|51|302|312||50.0 21|74|74|314|367||530.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAGGAGCCTACTATAGTCTTTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARGAYYSLYYAMDYW GQGTSVTVSS_ ::::0:75:105:156:177:288:1:302:302:-1:-6:312:314:-1:336:367::
105 740 0.00279574 144 0.00480128 GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGAGGATGGTGAAACTAAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGAGCCCTCTATGATGGTTACTACTTGGGTTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-2*00(2920.3) IGHD2-3*00(85) IGHJ3*00(457.8) nan 0|294|314|0|294||2940.0 17|34|51|298|315||85.0 22|68|68|321|367||460.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAGACTACTAT 45 ATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGAGGATGGTGAAACT 45 AAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTGCTAGAGCCCTCTATGATGGTTACTACTTGGGTTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGAELVKPGASVKLSCTAS GFNIKDYY MHWVKQRTEQGLEWIGR IDPEDGET KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CARALYDGYYLGWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:298:0:0:315:321:-2:336:367::
106 734 0.00277308 63 0.00210056 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAAGGGCAGCTCAGGCTACGTGGGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2890),IGHV1-62-300(2832) IGHD3-2*00(75) IGHJ4*00(518.2) IGHA*00(308.1) 0|294|314|0|294||2940.0;0|294|314|0|294|SA63TSC284T|2882.0 19|34|48|299|314||75.0 22|74|74|318|370||520.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAAGGGCAGCTCAGGCTACGTGGGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARKGSSGYVGYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:299:-3:2:314:318:-2:339:370::
109 700 0.00264462 108 0.00360096 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATCGGGGTGGGACGGGAGTTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2943.7) IGHD4-1*00(35) IGHJ2*00(458.3) nan 0|296|314|0|296||2960.0 16|23|33|300|307||35.0 22|68|68|312|358||460.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATCGGGGTGGGACGGGAGTTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARSGWDGSYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:300:-5:1:307:312:-2:327:358::
110 688 0.00259929 91 0.00303414 GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTCACTGACTACAACATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTAATTAATCCTAACTATGGTACTACTAGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAAAGGGGGGACCCTGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-39*00(2904.8) IGHD4-1*00(25) IGHJ3*00(437.1) nan 0|292|314|0|292||2920.0 17|22|33|297|302||25.0 24|68|68|305|349||440.0 nan GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTCACTGACTACAAC 45 ATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTA 45 ATTAATCCTAACTATGGTACTACT 45 AGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAAAGGGGGGACCCTGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EFQLQQSGPELVKPGASVKISCKAS GYSFTDYN MNWVKQSNGKSLEWIGV INPNYGTT SYNQKFKGKATLTVDQSSSTAYMQLNSLTSEDSAVYY CAKGGTLFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:-2:292:297:-6:0:302:305:-4:318:349::
113 644 0.00243305 57 0.00190051 CAGGTGCAGCTGAAGCAGTCAGGACCTGGCCTAGTGCAGCCCTCACAGAGCCTGTCCATCACCTGCACAGTCTCTGGTTTCTCATTAAGTAGCTATGGTGTACACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTGATATGGAGTGGTGGAAGCACAGACTATAATGCAGCTTTCATATCCAGACTGAGCATCAGCAAGGACAATTCCAAGAGCCAAGTTTTCTTTAAAATGAACAGTCTGCAAGTTGATGACACAGCCATATATTACTGTGCCAGAAATGGGAATTACGACGGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV2-2*00(2850.4) IGHD2-400(45),IGHD2-700(40) IGHJ3*00(499.8) IGHA*00(308.2) 0|294|313|0|294|SC88GSC259T|2882.0 26|35|51|298|307||45.0;27|35|51|299|307||40.0 18|68|68|308|358||500.0 nan CAGGTGCAGCTGAAGCAGTCAGGACCTGGCCTAGTGCAGCCCTCACAGAGCCTGTCCATCACCTGCACAGTCTCT 45 GGTTTCTCATTAAGTAGCTATGGT 45 GTACACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTG 45 ATATGGAGTGGTGGAAGCACA 45 GACTATAATGCAGCTTTCATATCCAGACTGAGCATCAGCAAGGACAATTCCAAGAGCCAAGTTTTCTTTAAAATGAACAGTCTGCAAGTTGATGACACAGCCATATATTAC 45 TGTGCCAGAAATGGGAATTACGACGGGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLKQSGPGLVQPSQSLSITCTVS GFSLSSYG VHWVRQSPGKGLEWLGV IWSGGST DYNAAFISRLSISKDNSKSQVFFKMNSLQVDDTAIYY CARNGNYDGAWFAYW GQGTLVTVSA_ ::::0:75:99:150:171:282:1:294:298:-9:1:307:308:2:327:358::
115 628 0.0023726 111 0.00370099 GAGGTGAAGCTGATGGAATCTGGAGGAGGCTTGGTACAGCCTGGGGCTTCTCTGAGACTCTCCTGTGCAGCTTCTGGATTCACCTTTACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGGAAGGCACCTGAGTGGTTGGCTTTGATTAGAAACAAAGCTAATGGTTACACAACAGAGTATACTGCATCTGTTAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAACATCCTCTATCTTCAAATGAACACCCTGAGGGCTGAGGACAGTGCCACTTATTACTGTGTAAAAGCGAGCAGGGACGCCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV7-4*00(2994.4) IGHD4-100(30),IGHD6-200(26) IGHJ2*00(467.8) nan 0|302|326|0|302||3020.0 17|23|33|307|313||30.0;12|20|87|304|312|SA16G|26.0 21|68|68|314|361||470.0 nan GAGGTGAAGCTGATGGAATCTGGAGGAGGCTTGGTACAGCCTGGGGCTTCTCTGAGACTCTCCTGTGCAGCTTCT 45 GGATTCACCTTTACTGATTACTAC 45 ATGAGCTGGGTCCGCCAGCCTCCAGGGAAGGCACCTGAGTGGTTGGCTTTG 45 ATTAGAAACAAAGCTAATGGTTACACAACA 45 GAGTATACTGCATCTGTTAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAACATCCTCTATCTTCAAATGAACACCCTGAGGGCTGAGGACAGTGCCACTTATTAC 45 TGTGTAAAAGCGAGCAGGGACGCCTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVKLMESGGGLVQPGASLRLSCAAS GFTFTDYY MSWVRQPPGKAPEWLAL IRNKANGYTT EYTASVKGRFTISRDNSQNILYLQMNTLRAEDSATYY CVKASRDAYFDYW GQGTTLTVSS_ ::::0:75:99:150:180:291:-4:302:307:-6:1:313:314:-1:330:361::
116 609 0.00230082 75 0.00250067 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGTAACTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2914.6) nan IGHJ3*00(467.2) nan 0|293|314|0|293||2930.0 nan 21|68|68|296|343||470.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGTAACTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CASNWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285👎293:::::296:-1:312:343::
117 606 0.00228949 98 0.00326754 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATAACCTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGATATTTATCCTGGTAGTGGTAGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGAGGGTTCTATTACTACGGTAGTAGCTACGATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-55*00(2919.4) IGHD1-1*00(90) IGHJ4*00(489.6) nan 0|294|314|0|294||2940.0 25|43|69|300|318||90.0 22|74|74|318|370|ST25G|491.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATAACCTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAT 45 ATTTATCCTGGTAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGAGGGTTCTATTACTACGGTAGTAGCTACGATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKMSCKAS GYTFTSYW ITWVKQRPGQGLEWIGD IYPGSGST NYNEKFKSKATLTVDTSSSTAYMQLSSLTSEDSAVYY CARGFYYYGSSYDAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:300:-2:-3:318:318:-2:339:370::
119 570 0.00215348 80 0.00266738 GAGGTCCAGCTGCAACAATCTGGACCGGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGATGAAACAGAGCCATGGACAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATAGAACTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCGGCGAGGAGGGGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2707.7) nan IGHJ2*00(399.2) IGHG2C*00(64.8) 0|290|314|0|290|ST26GSG108ASG113ASA126CSG242ASG245A|2726.0 nan 28|68|68|303|343||400.0 nan GAGGTCCAGCTGCAACAATCTGGACCGGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGATGAAACAGAGCCATGGACAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATAGAACTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCGGCGAGGAGGGGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWMKQSHGQSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYIELRSLTSEDSAVYY CAARRGDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:::::303:-8:312:343::
120 567 0.00214214 87 0.00290077 GACGTGAAGCTGGTGGAGTCTGGGGAAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATGCCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAGTGGTGGTGATTACATCTACTATGCAGACACTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAGGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTACAAGAGACAGCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-9-1*00(2915.6) IGHD3-200(25),IGHD5-800(25) IGHJ4*00(498.8) nan 0|294|314|0|294||2940.0 17|22|48|294|299||25.0;30|35|87|294|299||25.0 24|74|74|299|349||500.0 nan GACGTGAAGCTGGTGGAGTCTGGGGAAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCT 45 GGATTCACTTTCAGTAGCTATGCC 45 ATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATAC 45 ATTAGTAGTGGTGGTGATTACATC 45 TACTATGCAGACACTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAGGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTAC 45 TGTACAAGAGACAGCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 DVKLVESGEGLVKPGGSLKLSCAAS GFTFSSYA MSWVRQTPEKRLEWVAY ISSGGDYI YYADTVKGRFTISRDNARNTLYLQMSSLKSEDTAMYY CTRDSYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:294:-1:-10:299:299:-4:318:349::
121 550 0.00207792 78 0.00260069 CAGGTGCAGCTGAAGGAGTCAGGACCTGGCCTGGTGGCGCCCTCACAGAGCCTGTCCATCACATGCACCGTCTCAGGGTTCTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGTAGTGATATGGAGTGATGGAAGCACAACCTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTCCAAACTGATGACACAGCCATGTACTACTGTGCCAGACAGGGTAGTAACTACGTGGGGGTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV2-6*00(2894.9) IGHD2-500(60),IGHD2-600(60),IGHD1-1*00(56) IGHJ3*00(419.1) nan 0|291|311|0|291||2910.0 24|36|51|296|308||60.0;24|36|51|296|308||60.0;34|48|69|294|308|SG41A|56.0 23|68|68|310|355|ST25G|421.0 nan CAGGTGCAGCTGAAGGAGTCAGGACCTGGCCTGGTGGCGCCCTCACAGAGCCTGTCCATCACATGCACCGTCTCA 45 GGGTTCTCATTAACCAGCTATGGT 45 GTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGTAGTG 45 ATATGGAGTGATGGAAGCACA 45 ACCTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTCCAAACTGATGACACAGCCATGTACTAC 45 TGTGCCAGACAGGGTAGTAACTACGTGGGGGTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLKESGPGLVAPSQSLSITCTVS GFSLTSYG VHWVRQPPGKGLEWLVV IWSDGST TYNSALKSRLSISKDNSKSQVFLKMNSLQTDDTAMYY CARQGSNYVGVAYW GQGTLVTVSA_ ::::0:75:99:150:171:282:0:291:296:-7:2:308:310:-3:324:355::
122 544 0.00205525 65 0.00216724 CAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAAGCTTCTGGCTACGCATTCAGTAGCTACTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACAGATTTATCCTGGAGATGGTGATACTAACTACAACGGAAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTCTGTGCAGGGGCCTTTGGTCCCCTTTACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-80*00(2887.8) IGHD2-500(25),IGHD2-600(25),IGHD4-1*00(25) IGHJ2*00(390.2) IGHG3*00(79.4) 0|291|314|0|291||2910.0 15|20|51|293|298||25.0;15|20|51|293|298||25.0;0|5|33|301|306||25.0 26|68|68|307|349|SG28T|391.0 nan CAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAAGCTTCT 45 GGCTACGCATTCAGTAGCTACTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACAG 45 ATTTATCCTGGAGATGGTGATACT 45 AACTACAACGGAAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAGGGGCCTTTGGTCCCCTTTACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELVKPGASVKISCKAS GYAFSSYW MNWVKQRPGKGLEWIGQ IYPGDGDT NYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CAGAFGPLYYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-3:291:293:2:-14:298:307:-6:318:349::
124 528 0.0019948 36 0.00120032 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGAAGGGGGGATGGCTACTACGGGGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2844.3) IGHD2-3*00(51) IGHJ3*00(449.8) IGHA*00(308.1) 0|294|314|0|294||2940.0 22|35|51|300|313|ST27C|51.0 23|68|68|316|361||450.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGAAGGGGGGATGGCTACTACGGGGGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CARRGDGYYGGFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:300:-5:1:313:316:-3:330:361::
126 517 0.00195324 67 0.00223393 CAGGTGCAGCTGAAGCAGTCAGGACCTGGCCTAGTGCAGCCCTCACAGAGCCTGTCCATAACCTGCACAGTCTCTGGTTTCTCATTAACTAGCTATGGTGTACACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTGATATGGAGAGGTGGAAGCACAGACTACAATGCAGCTTTCATGTCCAGACTGAGCATCACCAAGGACAACTCCAAGAGCCAAGTTTTCTTTAAAATGAACAGTCTGCAAGCTGATGACACTGCCATATACTACTGTGCCAAAAATGGTAACTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV2-5*00(2926.7) IGHD2-8*00(30) IGHJ4*00(518.1) nan 0|294|313|0|294||2940.0 25|31|51|294|300||30.0 22|74|74|300|352||520.0 nan CAGGTGCAGCTGAAGCAGTCAGGACCTGGCCTAGTGCAGCCCTCACAGAGCCTGTCCATAACCTGCACAGTCTCT 45 GGTTTCTCATTAACTAGCTATGGT 45 GTACACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTG 45 ATATGGAGAGGTGGAAGCACA 45 GACTACAATGCAGCTTTCATGTCCAGACTGAGCATCACCAAGGACAACTCCAAGAGCCAAGTTTTCTTTAAAATGAACAGTCTGCAAGCTGATGACACTGCCATATACTAC 45 TGTGCCAAAAATGGTAACTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLKQSGPGLVQPSQSLSITCTVS GFSLTSYG VHWVRQSPGKGLEWLGV IWRGGST DYNAAFMSRLSITKDNSKSQVFFKMNSLQADDTAIYY CAKNGNYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:171:282:1:294:294:-8:-3:300:300:-2:321:352::
129 500 0.00188902 76 0.00253401 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGAGACTGGGACAACCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-69*00(2923.4) IGHD4-1*00(40) IGHJ1*00(508.8) nan 0|294|314|0|294||2940.0 14|22|33|295|303||40.0 22|73|73|307|358||510.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGAGACTGGGACAACCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQPGAELVMPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGE IDPSDSYT NYNQKFKGKSTLTVDKSSSTAYMQLSSLTSEDSAVYY CARDWDNHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:295:-3:0:303:307:-2:327:358::
130 489 0.00184746 78 0.00260069 GACGTGAAGCTGGTGGAGTCTGGGGAAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATGCCATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATACATTAGTAGTGGTGGTGATTACATCTACTATGCAGACACTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAGGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTACAAGGGGGGGTAGTAGCTACGAGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-9-1*00(2890.4) nan IGHJ1*00(521.2) nan 0|293|314|0|293||2930.0 nan 15|73|73|300|358|ST24GSG25A|522.0 nan GACGTGAAGCTGGTGGAGTCTGGGGAAGGCTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCT 45 GGATTCACTTTCAGTAGCTATGCC 45 ATGTCTTGGGTTCGCCAGACTCCAGAGAAGAGGCTGGAGTGGGTCGCATAC 45 ATTAGTAGTGGTGGTGATTACATC 45 TACTATGCAGACACTGTGAAGGGCCGATTCACCATCTCCAGAGACAATGCCAGGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTAC 45 TGTACAAGGGGGGGTAGTAGCTACGAGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 DVKLVESGEGLVKPGGSLKLSCAAS GFTFSSYA MSWVRQTPEKRLEWVAY ISSGGDYI YYADTVKGRFTISRDNARNTLYLQMSSLKSEDTAMYY CTRGGSSYEYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285👎293:::::300:5:327:358::
131 485 0.00183235 87 0.00290077 GAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTTAACATTAAAGACGACTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGGATTGATCCTGAGAATGGTGATACTGAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTACTACATGGAGGTATGATGGTTACTCCCTTTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-4*00(2943.8) IGHD2-3*00(65) IGHJ4*00(529.1) IGHG3*00(80.4) 0|299|314|0|299|ST296G|2961.0 19|32|51|300|313||65.0 21|74|74|317|370||530.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTTAACATTAAAGACGACTAT 45 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGG 45 ATTGATCCTGAGAATGGTGATACT 45 GAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTACTACATGGAGGTATGATGGTTACTCCCTTTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 EVQLQQSGAELVRPGASVKLSCTAS GFNIKDDY MHWVKQRPEQGLEWIGW IDPENGDT EYASKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CTTWRYDGYSLYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:5:299:300:-2:-2:313:317:-1:339:370::
134 428 0.001617 22 0.000733529 GAGGTGCAGCTGGTGGAGTCTGGGGGAGACTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTGGTGGTGGTGGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACGGGGCTCTACCTGGGACGGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-6*00(2763.4) IGHD4-100(31),IGHD5-500(30),IGHD1-1*00(28) IGHJ1*00(479.5) IGHA*00(307.5) 0|294|314|0|294|SA156GSA165G|2882.0 11|20|33|301|310|SA14C|31.0;12|18|30|301|307||30.0;3|12|69|298|306|DA6|28.0 22|73|73|310|361|ST24G|481.0 nan GAGGTGCAGCTGGTGGAGTCTGGGGGAGACTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCT 45 GGATTCACTTTCAGTAGCTATGGC 45 ATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACC 45 ATTAGTGGTGGTGGTGGTTACACC 45 TACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTAC 45 TGTGCAAGACGGGGCTCTACCTGGGACGGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLVESGGDLVKPGGSLKLSCAAS GFTFSSYG MSWVRQTPDKRLEWVAT ISGGGGYT YYPDSVKGRFTISRDNAKNTLYLQMSSLKSEDTAMYY CARRGSTWDGYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:301:0:-2:310:310:-2:330:361::
135 420 0.00158677 59 0.00196719 CAAGTGCAGATGAAGGAGTCAGGACCTGACCTTGTGCAGCCATCACAGACTCTGTCTCTCACCTGCACTGTCTCTGGGTTCTCATTAAGTAGCTATGGTGTACATTGGTTTCGCAAGCCTCCGAGAAAGGGATTGGAATGGTTGGGAGGAATATGGTCTGGTGGAAGCATATACTATACTCCAGCTCTCAGTTCCCGACTGAGTGTCAGCAGGGACACCTCTAAGAGCCAAGTTTTCTTTAAAATGAGCAGTCTGCAAAGTGAAGACACGGCTGTGTACCACTGTGCCAGATATGGTAACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV2-7*00(2925.7) nan IGHJ4*00(508.7) nan 0|294|313|0|294||2940.0 nan 23|74|74|298|349||510.0 nan CAAGTGCAGATGAAGGAGTCAGGACCTGACCTTGTGCAGCCATCACAGACTCTGTCTCTCACCTGCACTGTCTCT 45 GGGTTCTCATTAAGTAGCTATGGT 45 GTACATTGGTTTCGCAAGCCTCCGAGAAAGGGATTGGAATGGTTGGGAGGA 45 ATATGGTCTGGTGGAAGCATA 45 TACTATACTCCAGCTCTCAGTTCCCGACTGAGTGTCAGCAGGGACACCTCTAAGAGCCAAGTTTTCTTTAAAATGAGCAGTCTGCAAAGTGAAGACACGGCTGTGTACCAC 45 TGTGCCAGATATGGTAACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQMKESGPDLVQPSQTLSLTCTVS GFSLSSYG VHWFRKPPRKGLEWLGG IWSGGSI YYTPALSSRLSVSRDTSKSQVFFKMSSLQSEDTAVYH CARYGNYAMDYW GQGTSVTVSS_ ::::0:75:99:150:171:282:1:294:::::298:-3:318:349::
136 413 0.00156033 58 0.00193385 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACATTCACTGGCTACTGGATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAGATTTTACCTGGAAGTGGTAGTACTAACTACAATGAGAAGTTCAAGGGCGAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAAGATGGGGGCTAACTGGTTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(2903.3) IGHD4-1*00(45) IGHJ2*00(428.4) IGHG2C*00(63.9) 0|295|314|0|295|SA198G|2921.0 10|19|33|299|308||45.0 25|68|68|309|352||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 GGCTACACATTCACTGGCTACTGG 45 ATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAG 45 ATTTTACCTGGAAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGGGCGAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGATGGGGGCTAACTGGTTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT GYTFTGYW IEWVKQRPGHGLEWIGE ILPGSGST NYNEKFKGEATFTADTSSNTAYMQLSSLTTEDSAIYY CARWGLTGFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:299:1:-3:308:309:-5:321:352::
137 413 0.00156033 59 0.00196719 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAAGAGCTGACTATGATTACCTCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(3018.6) IGHD2-4*00(55) IGHJ1*00(528) nan 0|303|321|0|303||3030.0 20|31|51|304|315||55.0 20|73|73|317|370||530.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAAGAGCTGACTATGATTACCTCTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARRADYDYLYWYFDVW GTGTTVTVSS_ ::::0:75:105:156:177:288:2:303:304:-3:-3:315:317:0:339:370::
138 412 0.00155655 66 0.00220059 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGAAGGGGATTCTTACTATACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2922) IGHD1-100(31),IGHD2-300(30),IGHD2-6*00(30) IGHJ2*00(488.2) IGHG2C*00(65.2) 0|294|314|0|294||2940.0 24|33|69|300|309|SA26C|31.0;27|33|51|303|309||30.0;4|10|51|303|309||30.0 19|68|68|309|358||490.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGAAGGGGATTCTTACTATACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CARRGFLLYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:300:-1:-13:309:309:1:327:358::
141 332 0.00125431 47 0.00156708 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGATGGGGTAACTACGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2932) IGHD2-800(50),IGHD2-500(45),IGHD2-6*00(45) IGHJ3*00(448) nan 0|295|314|0|295||2950.0 25|35|51|297|307||50.0;26|35|51|298|307||45.0;26|35|51|298|307||45.0 23|68|68|307|352||450.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGATGGGGTAACTACGGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CARWGNYGFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:1:295:297:-8:1:307:307:-3:321:352::
143 310 0.00117119 43 0.00143372 GATGTACAGCTTCAGGAGTCAGGACCTGGCCTCGTGAAACCTTCTCAGTCTCTGTCTCTCACCTGCTCTGTCACTGGCTACTCCATCACCAGTGGTTATTACTGGAACTGGATCCGGCAGTTTCCAGGAAACAAACTGGAATGGATGGGCTACATAAGCTACGATGGTAGCAATAACTACAACCCATCTCTCAAAAATCGAATCTCCATCACTCGTGACACATCTAAGAACCAGTTTTTCCTGAAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTACTGTGCAATCCCCCATTACTACGGTAGTAGCTACGAGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV3-6*00(2902.3) IGHD1-1*00(105) IGHJ3*00(438) nan 0|292|316|0|292||2920.0 26|47|69|298|319||105.0 24|68|68|320|364||440.0 nan GATGTACAGCTTCAGGAGTCAGGACCTGGCCTCGTGAAACCTTCTCAGTCTCTGTCTCTCACCTGCTCTGTCACT 45 GGCTACTCCATCACCAGTGGTTATTAC 45 TGGAACTGGATCCGGCAGTTTCCAGGAAACAAACTGGAATGGATGGGCTAC 45 ATAAGCTACGATGGTAGCAAT 45 AACTACAACCCATCTCTCAAAAATCGAATCTCCATCACTCGTGACACATCTAAGAACCAGTTTTTCCTGAAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTAC 45 TGTGCAATCCCCCATTACTACGGTAGTAGCTACGAGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 DVQLQESGPGLVKPSQSLSLTCSVT GYSITSGYY WNWIRQFPGNKLEWMGY ISYDGSN NYNPSLKNRISITRDTSKNQFFLKLNSVTTEDTATYY CAIPHYYGSSYEFAYW GQGTLVTVSA_ ::::0:75:102:153:174:285:-4:292:298:-3:1:319:320:-4:333:364::
146 294 0.00111074 46 0.00153374 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATCGGCTAAATCAAAACTCGTATTTATTACTACGGTAGTAGCTACGGGGGACGGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-69*00(2933.7) IGHD1-1*00(125) IGHJ1*00(465.2) nan 0|296|314|0|296||2960.0 22|47|69|314|339||125.0 22|73|73|343|394|ST24G|481.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATCGGCTAAATCAAAACTCGTATTTATTACTACGGTAGTAGCTACGGGGGACGGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQPGAELVMPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGE IDPSDSYT NYNQKFKGKSTLTVDKSSSTAYMQLSSLTSEDSAVYY CARSAKSKLVFITTVVATGDGYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:2:296:314:1:1:339:343:-2:363:394::
148 246 0.000929396 48 0.00160043 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAAGGGGACTGGGACTCCCTTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2975.1) IGHD4-1*00(48) IGHJ4*00(527.9) IGHG2B*00(60.1) 0|299|321|0|299||2990.0 14|27|33|302|314|DG22|48.0 21|74|74|314|367||530.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAAGGGGACTGGGACTCCCTTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARRGLGLPYYAMDYW GQGTSVTVSS_ ::::0:75:105:156:177:288:-2:299:302:-3:5:314:314:-1:336:367::
149 245 0.000925618 51 0.00170045 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGATCGAGATACTACGGTAGCCATGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2946.4) IGHD1-1*00(55) IGHJ2*00(408.6) IGHG2B*00(61.4) 0|296|314|0|296||2960.0 28|39|69|300|311||55.0 27|68|68|314|355||410.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGATCGAGATACTACGGTAGCCATGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CARSRYYGSHDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:300:-5:-7:311:314:-7:324:355::
150 241 0.000910506 37 0.00123366 CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTAAGGCCTGGGACTTCAGTGAAGATGTCCTGCAAGGCTTCTGGATACACCTTCACTAACTACTGGATAGGTTGGGCAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGATATTTACCCTGGAGGTGGTTATACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGTTCAGCAGCCTGACATCTGAGGACTCTGCCATCTATTACTGTGCAAGAGGGGGGCAACTCTTGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-63*00(2918.4) nan IGHJ2*00(499.1) IGHG2B00(54.6),IGHG2C00(54.6) 0|294|314|0|294||2940.0 nan 18|68|68|308|358||500.0 ; CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTAAGGCCTGGGACTTCAGTGAAGATGTCCTGCAAGGCTTCT 45 GGATACACCTTCACTAACTACTGG 45 ATAGGTTGGGCAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAT 45 ATTTACCCTGGAGGTGGTTATACT 45 AACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGTTCAGCAGCCTGACATCTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGAGGGGGGCAACTCTTGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELVRPGTSVKMSCKAS GYTFTNYW IGWAKQRPGHGLEWIGD IYPGGGYT NYNEKFKGKATLTADKSSSTAYMQFSSLTSEDSAIYY CARGGQLLYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:::::308:2:327:358::
152 231 0.000872726 35 0.00116698 CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACAGCTTCACAAGCTACTATATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGGATTTATCCTGGAAGTGGTAATACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATGTCTACTATGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-66*00(2934) IGHD2-700(50),IGHD2-800(50),IGHD2-4*00(45) IGHJ4*00(518.5) IGHG2B00(54.9),IGHG2C00(54.9) 0|295|314|0|295||2950.0 17|27|51|296|306||50.0;17|27|51|296|306||50.0;17|26|51|296|305||45.0 22|74|74|306|358||520.0 ; CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACAGCTTCACAAGCTACTAT 45 ATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGG 45 ATTTATCCTGGAAGTGGTAATACT 45 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATGTCTACTATGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYSFTSYY IHWVKQRPGQGLEWIGW IYPGSGNT KYNEKFKGKATLTADTSSSTAYMQLSSLTSEDSAVYY CARCLLWYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:1:295:296:0:-7:306:306:-2:327:358::
154 216 0.000816055 28 0.000933582 CAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAAGCTTCTGGCTACGCATTCAGTAGCTACTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACAGATTTATCCTGGAGATGGTGATACTAACTACAACGGAAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATACTACTATGGTAACTACGACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-80*00(2925.6) IGHD2-8*00(85) IGHJ2*00(478.4) IGHG2C*00(65.1) 0|295|314|0|295||2950.0 18|35|51|296|313||85.0 20|68|68|313|361||480.0 nan CAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAAGCTTCT 45 GGCTACGCATTCAGTAGCTACTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACAG 45 ATTTATCCTGGAGATGGTGATACT 45 AACTACAACGGAAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATACTACTATGGTAACTACGACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELVKPGASVKISCKAS GYAFSSYW MNWVKQRPGKGLEWIGQ IYPGDGDT NYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CARYYYGNYDYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:296:-1:1:313:313:0:330:361::
155 210 0.000793387 33 0.00110029 CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTAAGGCCTGGGACTTCAGTGAAGATGTCCTGCAAGGCTTCTGGATACACCTTCACTAACTACTGGATAGGTTGGGCAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGATATTTACCCTGGAGGTGGTTATACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGTTCAGCAGCCTGACATCTGAGGACTCTGCCATCTATTACTGTGCAAGAGGGGGGCAACTCTTGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-63*00(2911.3) nan IGHJ2*00(498.6) IGHG2C*00(65) 0|294|314|0|294||2940.0 nan 18|68|68|308|358||500.0 nan CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTAAGGCCTGGGACTTCAGTGAAGATGTCCTGCAAGGCTTCT 45 GGATACACCTTCACTAACTACTGG 45 ATAGGTTGGGCAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAT 45 ATTTACCCTGGAGGTGGTTATACT 45 AACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGTTCAGCAGCCTGACATCTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGAGGGGGGCAACTCTTGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELVRPGTSVKMSCKAS GYTFTNYW IGWAKQRPGHGLEWIGD IYPGGGYT NYNEKFKGKATLTADKSSSTAYMQFSSLTSEDSAIYY CARGGQLLYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:::::308:2:327:358::
156 189 0.000714048 45 0.0015004 GAGGTTCAGCTGCAGCAGTCTGTGGCAGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAAACACCTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGCGAATGGTAATCCTAAATATGCCCCGAAGTTCCAGGGCAAGGCCACTATAACTGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCATCTATTACTGTGCTAGACAGCTCAGGCTACCTACGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-3*00(2892.6) IGHD3-2*00(66) IGHJ2*00(498.5) IGHG2B*00(62.1) 0|294|314|0|294|SA171C|2911.0 19|35|48|294|310|SG32C|66.0 18|68|68|311|361||500.0 nan GAGGTTCAGCTGCAGCAGTCTGTGGCAGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAAACACCTAT 45 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGCGAATGGTAATCCT 45 AAATATGCCCCGAAGTTCCAGGGCAAGGCCACTATAACTGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCATCTATTAC 45 TGTGCTAGACAGCTCAGGCTACCTACGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSVAELVRPGASVKLSCTAS GFNIKNTY MHWVKQRPEQGLEWIGR IDPANGNP KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAIYY CARQLRLPTYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:294:-3:3:310:311:2:330:361::
157 189 0.000714048 33 0.00110029 GAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTCACTGGCTACTACATGAACTGGGTGAAGCAAAGTCCTGAAAAGAGCCTTGAGTGGATTGGAGAGATTAATCCTAGCACTGGTGGTACTACCTACAACCAGAAGTTCAAGGCCAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAAGAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGAGAGTTACCCCCATATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-42*00(2920.7) IGHD2-800(35),IGHD2-500(30),IGHD2-6*00(30) IGHJ4*00(558.8) nan 0|294|314|0|294||2940.0 2|9|51|295|302||35.0;2|8|51|295|301||30.0;2|8|51|295|301||30.0 18|74|74|305|361||560.0 nan GAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTCACTGGCTACTAC 45 ATGAACTGGGTGAAGCAAAGTCCTGAAAAGAGCCTTGAGTGGATTGGAGAG 45 ATTAATCCTAGCACTGGTGGTACT 45 ACCTACAACCAGAAGTTCAAGGCCAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAAGAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGAGAGTTACCCCCATATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYSFTGYY MNWVKQSPEKSLEWIGE INPSTGGT TYNQKFKAKATLTVDKSSSTAYMQLKSLTSEDSAVYY CARELPPYYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:295:15:-25:302:305:2:330:361::
158 169 0.000638488 37 0.00123366 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTACCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCGGCGAGGAGGGGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2852.3) nan IGHJ2*00(398.8) IGHG2B*00(58.9) 0|290|314|0|290|SG175C|2871.0 nan 28|68|68|303|343||400.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 ACCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCGGCGAGGAGGGGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT TYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CAARRGDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:::::303:-8:312:343::
159 153 0.000578039 36 0.00120032 GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGAGGATGGTGAAACTAAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGAGCCCTCTATGATGGTTACTACTTGGGTTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-2*00(2911.8) IGHD2-3*00(85) IGHJ3*00(457.5) IGHG2B*00(62.1) 0|294|314|0|294||2940.0 17|34|51|298|315||85.0 22|68|68|321|367||460.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAGACTACTAT 45 ATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGAGGATGGTGAAACT 45 AAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTGCTAGAGCCCTCTATGATGGTTACTACTTGGGTTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGAELVKPGASVKLSCTAS GFNIKDYY MHWVKQRTEQGLEWIGR IDPEDGET KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CARALYDGYYLGWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:298:0:0:315:321:-2:336:367::
160 150 0.000566705 23 0.000766871 CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACAGCTTCACAAGCTACTATATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGGATTTATCCTGGAAGTGGTAATACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATGTCTACTATGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-66*00(2929.7) IGHD2-700(50),IGHD2-800(50),IGHD2-4*00(45) IGHJ4*00(519.4) IGHG2C*00(67.8) 0|295|314|0|295||2950.0 17|27|51|296|306||50.0;17|27|51|296|306||50.0;17|26|51|296|305||45.0 22|74|74|306|358||520.0 nan CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACAGCTTCACAAGCTACTAT 45 ATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGG 45 ATTTATCCTGGAAGTGGTAATACT 45 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATGTCTACTATGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYSFTSYY IHWVKQRPGQGLEWIGW IYPGSGNT KYNEKFKGKATLTADTSSSTAYMQLSSLTSEDSAVYY CARCLLWYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:1:295:296:0:-7:306:306:-2:327:358::
161 138 0.000521369 18 0.00060016 CAGATGCAGCTTCAGGAGTCAGGACCTGGCCTGGTGAAACCCTCACAGTCACTCTTCCTTACCTGCTCTATTACTGGTTTCCCCATCACCAGTGGTTACTACTGGATCTGGATCCGTCAGTCACCTGGGAAACCCCTAGAATGGATGGGGTACATCACTCATAGTGGGGAAACTTTCTACAACCCATCTCTCCAGAGCCCCATCTCCATTACTAGAGAAACGTCAAAGAACCAGTTCTTCCTCCAATTGAACTCTGTGACCACAGAGGACACAGCCATGTATTACTGTGCAGGAGACAGATCTGGGTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV12-3*00(2911) IGHD2-300(30),IGHD2-700(30),IGHD2-8*00(30) IGHJ1*00(519.2) nan 0|294|314|0|294||2940.0 14|20|51|297|303||30.0;14|20|51|297|303||30.0;14|20|51|297|303||30.0 21|73|73|306|358||520.0 nan CAGATGCAGCTTCAGGAGTCAGGACCTGGCCTGGTGAAACCCTCACAGTCACTCTTCCTTACCTGCTCTATTACT 45 GGTTTCCCCATCACCAGTGGTTACTAC 45 TGGATCTGGATCCGTCAGTCACCTGGGAAACCCCTAGAATGGATGGGGTAC 45 ATCACTCATAGTGGGGAAACT 45 TTCTACAACCCATCTCTCCAGAGCCCCATCTCCATTACTAGAGAAACGTCAAAGAACCAGTTCTTCCTCCAATTGAACTCTGTGACCACAGAGGACACAGCCATGTATTAC 45 TGTGCAGGAGACAGATCTGGGTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QMQLQESGPGLVKPSQSLFLTCSIT GFPITSGYY WIWIRQSPGKPLEWMGY ITHSGET FYNPSLQSPISITRETSKNQFFLQLNSVTTEDTAMYY CAGDRSGYWYFDVW GTGTTVTVSS_ ::::0:75:102:153:174:285:0:294:297:3:-14:303:306:-1:327:358::
162 137 0.000517591 20 0.000666844 GATGTGCAGCTTCAGGAGTCAGGACCTGGCATGGTGAAACCTTCTCAGTCACTTTCCCTCACCTGCACTGTCACTGGCTACTCCATCACCAGTGGTTATGACTGGCACTGGATCCGACATTTTCCAGGAAACAAACTGGAGTGGATGGGCTACATAAGCTACAGTGGTAGCACTAACTACAACCCATCCCTCAAAAGTCGAATCTCCATCACTCATGACACATCTAAGAACCATTTCTTCCTGAAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTACTGTGCAAGAGGGGACTATGATTACGACGTCCCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV3-1*00(2911.9) IGHD2-4*00(85) IGHJ3*00(477.6) IGHG2B00(54.9),IGHG2C00(54.9) 0|294|314|0|294||2940.0 20|37|51|298|315||85.0 20|68|68|316|364||480.0 ; GATGTGCAGCTTCAGGAGTCAGGACCTGGCATGGTGAAACCTTCTCAGTCACTTTCCCTCACCTGCACTGTCACT 45 GGCTACTCCATCACCAGTGGTTATGAC 45 TGGCACTGGATCCGACATTTTCCAGGAAACAAACTGGAGTGGATGGGCTAC 45 ATAAGCTACAGTGGTAGCACT 45 AACTACAACCCATCCCTCAAAAGTCGAATCTCCATCACTCATGACACATCTAAGAACCATTTCTTCCTGAAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTAC 45 TGTGCAAGAGGGGACTATGATTACGACGTCCCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 DVQLQESGPGMVKPSQSLSLTCTVT GYSITSGYD WHWIRHFPGNKLEWMGY ISYSGST NYNPSLKSRISITHDTSKNHFFLKLNSVTTEDTATYY CARGDYDYDVPWFAYW GQGTLVTVSA_ ::::0:75:102:153:174:285:0:294:298:-3:3:315:316:0:333:364::
163 124 0.000468476 21 0.000700187 GAAGTGAAGCTTGAGGAGTCTGGAGGAGGCTTGGTGCAACCTGGAGGATCCATGAAACTCTCTTGTGCTGCCTCTGGATTCACTTTTAGTGACGCCTGGATGGACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAAATTAGAAACAAAGCTAATAATCATGCAACATACTATGCTGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAGCTTAAGAGCTGAAGACACTGGCATTTATTACTGTACCACCTGGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV6-6*00(2970.3) nan IGHJ2*00(487.2) nan 0|308|320|0|306|DG298DG299|2987.0 nan 18|68|68|302|352||500.0 nan GAAGTGAAGCTTGAGGAGTCTGGAGGAGGCTTGGTGCAACCTGGAGGATCCATGAAACTCTCTTGTGCTGCCTCT 45 GGATTCACTTTTAGTGACGCCTGG 45 ATGGACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTGAA 45 ATTAGAAACAAAGCTAATAATCATGCAACA 45 TACTATGCTGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAGCTTAAGAGCTGAAGACACTGGCATTTATTAC 45 TGTACCACCTGGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVKLEESGGGLVQPGGSMKLSCAAS GFTFSDAW MDWVRQSPEKGLEWVAE IRNKANNHAT YYAESVKGRFTISRDDSKSSVYLQMNSLRAEDTGIYY CTTWYYFDYW GQGTTLTVSS_ ::::0:75:99:150:180:291:8:306:::::302:2:321:352::
164 113 0.000426918 14 0.000466791 GATGTGCAGCTTCAGGAGTCAGGACCTGGCATGGTGAAACCTTCTCAGTCACTTTCCCTCACCTGCACTGTCACTGGCTACTCCATCACCAGTGGTTATGACTGGCACTGGATCCGACATTTTCCAGGAAACAAACTGGAGTGGATGGGCTACATAAGCTACAGTGGTAGCACTAACTACAACCCATCCCTCAAAAGTCGAATCTCCATCACTCATGACACATCTAAGAACCATTTCTTCCTGAAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTACTGTGCAAGAGGGGACTATGATTACGACGTCCCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV3-1*00(2912.2) IGHD2-4*00(85) IGHJ3*00(478.9) IGHG2C*00(67.2) 0|294|314|0|294||2940.0 20|37|51|298|315||85.0 20|68|68|316|364||480.0 nan GATGTGCAGCTTCAGGAGTCAGGACCTGGCATGGTGAAACCTTCTCAGTCACTTTCCCTCACCTGCACTGTCACT 45 GGCTACTCCATCACCAGTGGTTATGAC 45 TGGCACTGGATCCGACATTTTCCAGGAAACAAACTGGAGTGGATGGGCTAC 45 ATAAGCTACAGTGGTAGCACT 45 AACTACAACCCATCCCTCAAAAGTCGAATCTCCATCACTCATGACACATCTAAGAACCATTTCTTCCTGAAGTTGAATTCTGTGACTACTGAGGACACAGCCACATATTAC 45 TGTGCAAGAGGGGACTATGATTACGACGTCCCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 DVQLQESGPGMVKPSQSLSLTCTVT GYSITSGYD WHWIRHFPGNKLEWMGY ISYSGST NYNPSLKSRISITHDTSKNHFFLKLNSVTTEDTATYY CARGDYDYDVPWFAYW GQGTLVTVSA_ ::::0:75:102:153:174:285:0:294:298:-3:3:315:316:0:333:364::
165 112 0.00042314 16 0.000533476 CAGGTCCAGCTGCAGCAGTCTGGGCCTGAGCTGGTGAGGCCTGGGGTCTCAGTGAAGATTTCCTGCAAGGGTTCCGGCTACACATTCACTGATTATGCTATGCACTGGGTGAAACAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTTATTAGTACTTACTATGGTGATGCTAGCTACAACCAGAAGTTCAAGGACAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGACTGACATCTGAGGACTCTGCCGTCTATTACTGTGCAAGACTATGATTACGATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-67*00(2924.5) IGHD2-4*00(55) IGHJ4*00(537.9) nan 0|294|314|0|294||2940.0 21|32|51|294|305||55.0 20|74|74|305|359||540.0 nan CAGGTCCAGCTGCAGCAGTCTGGGCCTGAGCTGGTGAGGCCTGGGGTCTCAGTGAAGATTTCCTGCAAGGGTTCC 45 GGCTACACATTCACTGATTATGCT 45 ATGCACTGGGTGAAACAGAGTCATGCAAAGAGTCTAGAGTGGATTGGAGTT 45 ATTAGTACTTACTATGGTGATGCT 45 AGCTACAACCAGAAGTTCAAGGACAAGGCCACAATGACTGTAGACAAATCCTCCAGCACAGCCTATATGGAACTTGCCAGACTGACATCTGAGGACTCTGCCGTCTATTAC 45 TGTGCAAGACTATGATTACGATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGPELVRPGVSVKISCKGS GYTFTDYA MHWVKQSHAKSLEWIGV ISTYYGDA SYNQKFKDKATMTVDKSSSTAYMELARLTSEDSAVYY CARL*LR_YYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:294:-4:-2:305:305:0:328:359::
168 88 0.000332467 8 0.000266738 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGGATTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAATGGATTGGTAACATTTACCCTTCTGATAGTGAAACTCACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAACTGGGACGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-61*00(2904.8) IGHD4-1*00(40) IGHJ2*00(459.7) IGHM*00(81.3) 0|292|314|0|292||2920.0 15|23|33|292|300||40.0 22|68|68|300|346||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGGATTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAATGGATTGGTAAC 45 ATTTACCCTTCTGATAGTGAAACT 45 CACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAACTGGGACGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVRPGSSVKLSCKAS GYTFTSYW MDWVKQRPGQGLEWIGN IYPSDSET HYNQKFKDKATLTVDKSSSTAYMQLSSLTSEDSAVYY CATGTYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-2:292:292:-4:1:300:300:-2:315:346::
169 86 0.000324911 12 0.000400107 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCCCGGAACTATGGTTACGACGAGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2883.9) IGHD2-7*00(75) IGHJ2*00(508.8) nan 0|290|314|0|290||2900.0 20|35|51|295|310||75.0 17|68|68|310|361||510.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCCCGGAACTATGGTTACGACGAGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CARNYGYDEYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:295:-3:1:310:310:3:330:361::
170 81 0.000306021 15 0.000500133 CAGATGCAGCTTCAGGAGTCAGGACCTGGCCTGGTGAAACCCTCACAGTCACTCTTCCTTACCTGCTCTATTACTGGTTTCCCCATCACCAGTGGTTACTACTGGATCTGGATCCGTCAGTCACCTGGGAAACCCCTAGAATGGATGGGGTACATCACTCATAGTGGGGAAACTTTCTACAACCCATCTCTCCAGAGCCCCATCTCCATTACTAGAGAAACGTCAAAGAACCAGTTCTTCCTCCAATTGAACTCTGTGACCACAGAGGACACAGCCATGTATTACTGTGCAGGAGACAGCTCAGGCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV12-3*00(2913.9) IGHD3-2*00(50) IGHJ1*00(539) nan 0|294|314|0|294||2940.0 17|27|48|294|304||50.0 19|73|73|304|358||540.0 nan CAGATGCAGCTTCAGGAGTCAGGACCTGGCCTGGTGAAACCCTCACAGTCACTCTTCCTTACCTGCTCTATTACT 45 GGTTTCCCCATCACCAGTGGTTACTAC 45 TGGATCTGGATCCGTCAGTCACCTGGGAAACCCCTAGAATGGATGGGGTAC 45 ATCACTCATAGTGGGGAAACT 45 TTCTACAACCCATCTCTCCAGAGCCCCATCTCCATTACTAGAGAAACGTCAAAGAACCAGTTCTTCCTCCAATTGAACTCTGTGACCACAGAGGACACAGCCATGTATTAC 45 TGTGCAGGAGACAGCTCAGGCTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QMQLQESGPGLVKPSQSLFLTCSIT GFPITSGYY WIWIRQSPGKPLEWMGY ITHSGET FYNPSLQSPISITRETSKNQFFLQLNSVTTEDTAMYY CAGDSSGYWYFDVW GTGTTVTVSS_ ::::0:75:102:153:174:285:0:294:294:-1:-5:304:304:1:327:358::
171 60 0.000226682 7 0.000233396 GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGAGGATGGTGAAACTAAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGGGACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-2*00(2918.4) nan IGHJ2*00(478.5) IGHM*00(83) 0|293|314|0|293||2930.0 nan 20|68|68|295|343||480.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAGACTACTAT 45 ATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGAGGATGGTGAAACT 45 AAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTGCTAGGGACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGAELVKPGASVKLSCTAS GFNIKDYY MHWVKQRTEQGLEWIGR IDPEDGET KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CARDYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285👎293:::::295:0:312:343::
178 37 0.000139787 7 0.000233396 GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCAGGGTTCACTTTTAGTGGCTTCTGGATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGACATTAATTCTGATGGCAGTGCAATAAACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTCTGTATGAGATATGGTAACTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV11-2*00(2942.1) nan IGHJ1*00(539.3) IGHM*00(83) 0|297|316|0|297||2970.0 nan 16|73|73|298|355|SG19A|541.0 nan GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCA 45 GGGTTCACTTTTAGTGGCTTCTGG 45 ATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGAC 45 ATTAATTCTGATGGCAGTGCAATA 45 AACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTC 45 TGTATGAGATATGGTAACTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLLETGGGLVQPGGSRGLSCEGS GFTFSGFW MSWVRQTPGKTLEWIGD INSDGSAI NYAPSIKDRFTIFRDNDKSTLYLQMSNVRSEDTATYF CMRYGNYWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:1:297:::::298:4:324:355::
179 35 0.000132231 3 0.000100027 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(458.8) IGHD6-200(64),IGHD5-700(58),IGHD5-8*00(58) IGHJ2*00(496.8) nan 0|92|321|0|92||920.0 3|21|87|140|159|I8ASG17T|64.0;3|17|87|140|155|I8A|58.0;3|17|87|140|155|I8A|58.0 15|68|68|188|241|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS nan nan nan nan nan GQGTTLTVSS_ ::::0:75:::::::140:26:-37:159:188:5:210:241::
181 34 0.000128453 3 0.000100027 CAGGTGCAGCTTGTAGAGACCGGGGGAGGCTTGGTGAGGCCTGGAAATTCTCTGAAACTCTCCTGTGTCACCTCGAGATTCATTTTCAGTAACCACCGGATGCACTGGCTTCGCCAGCCTCCAGGGAAGAGGCTGGAGTGGATTGCTGTAATTACAGTCAAATCTGATAATTATGGAGCAAATTATGCAGAGTCTGTGAAAGGCAGATTCGCCATTTCAAGAGATGATTCAAAAAGCAGTGTCTACCTAGAGATGAACAGATTAAGAGAGGAAGACACTGCCACTTATTTTTGTAGTAGATTGGCACTACGGTAGTAGCCCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV13-2*00(2874) IGHD1-100(40),IGHD5-700(35),IGHD6-2*00(35) IGHJ2*00(480.4) IGHA*00(307.7) 0|301|320|0|301|ST68CSG75ASC82TST93C|2894.0 29|37|69|305|313||40.0;5|12|87|301|308||35.0;5|12|87|301|308||35.0 14|68|68|313|367|ST19CSA20C|482.0 nan CAGGTGCAGCTTGTAGAGACCGGGGGAGGCTTGGTGAGGCCTGGAAATTCTCTGAAACTCTCCTGTGTCACCTCG 45 AGATTCATTTTCAGTAACCACCGG 45 ATGCACTGGCTTCGCCAGCCTCCAGGGAAGAGGCTGGAGTGGATTGCTGTA 45 ATTACAGTCAAATCTGATAATTATGGAGCA 45 AATTATGCAGAGTCTGTGAAAGGCAGATTCGCCATTTCAAGAGATGATTCAAAAAGCAGTGTCTACCTAGAGATGAACAGATTAAGAGAGGAAGACACTGCCACTTATTTT 45 TGTAGTAGATTGGCACTACGGTAGTAGCCCTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLVETGGGLVRPGNSLKLSCVTS RFIFSNHR MHWLRQPPGKRLEWIAV ITVKSDNYGA NYAESVKGRFAISRDDSKSSVYLEMNRLREEDTATYF CSRLALR**PYFDYW GQGTTLTVSS_ ::::0:75:99:150:180:291:1:301:305:-6:-9:313:313:6:336:367::
182 33 0.000124675 5 0.000166711 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2931.6) IGHD2-800(60),IGHD2-700(55) IGHJ2*00(411.1) IGHA*00(67.6) 0|296|314|0|296||2960.0 17|29|51|298|310||60.0;17|28|51|298|309||55.0 20|68|68|310|358|ST25G|451.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTC 45 TGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGSGNT YYNEKFKGKATLTAEKSSSTAYMQLSSLTSEDSAVYF CARSVYYGNYVDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:298:0:-5:310:310:0:327:358::
186 30 0.000113341 4 0.000133369 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACTTCTACTATCCCGGGCTTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2866.1) IGHD2-400(40),IGHD2-700(40),IGHD2-8*00(40) IGHJ1*00(518.4) IGHA*00(303) 0|294|314|0|294||2940.0 17|25|51|296|304||40.0;17|25|51|296|304||40.0;17|25|51|296|304||40.0 21|73|73|312|364||520.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACTTCTACTATCCCGGGCTTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARLLLSRAYWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:296:0:-9:304:312:-1:333:364::
187 30 0.000113341 3 0.000100027 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTATTGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2847.3) IGHD4-1*00(35) IGHJ2*00(497.3) IGHM*00(70.8) 0|298|321|0|298|SC253GSC274TSC287TSC292T|2864.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTAT 45 TGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKISSVDTADIATYY CVRTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
189 28 0.000105785 1 3.33422e-05 GAGGTGCAGCTGGTGGAGTCTGGGGGAGACTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATGGCATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-6*00(871.5) IGHD1-100(40),IGHD5-700(40),IGHD5-8*00(40) IGHJ1*00(325) IGHA*00(309.5) 0|109|314|0|109|ST105G|1061.0 37|45|69|87|95||40.0;37|45|87|68|76||40.0;37|45|87|68|76||40.0 34|73|73|99|138||390.0 nan GAGGTGCAGCTGGTGGAGTCTGGGGGAGACTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCT 45 GGATTCACTTTCAGTAGCTATGGC 45 nan nan nan nan nan nan nan nan GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLVESGGDLVKPGGSLKLSCAAS GFTFSSYG nan nan nan nan GTGTTVTVSS_ ::::0:75:99::::::87:-14👎95:99:-14:107:138::
192 25 9.44508e-05 2 6.66844e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAAGATGGGGGCTAACTGGTTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(302.1) IGHD5-800(58),IGHD5-700(52),IGHD6-1*00(52) IGHJ2*00(427.5) IGHG2C*00(58.1) 0|91|314|0|91||910.0 10|34|87|62|84|DG15DG22ST26GSG30C|58.0;10|30|87|62|80|DG15DG22SC26G|52.0;10|30|87|62|80|DG15DG22SC26G|52.0 25|68|68|186|229||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 nan nan nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT nan nan nan nan nan GQGTTLTVSS_ ::::0:75:::::::62:19:-24:84:186:-5:198:229::
194 23 8.68948e-05 3 0.000100027 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATCGGGGTGGGACGGGAGTTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2937.5) IGHD4-1*00(35) IGHJ2*00(417.3) IGHA*00(310) 0|296|314|0|296||2960.0 16|23|33|300|307||35.0 22|68|68|312|358||460.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATCGGGGTGGGACGGGAGTTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARSGWDGSYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:2:296:300:-5:1:307:312:-2:327:358::
196 21 7.93387e-05 3 0.000100027 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACATTCACTGGCTACTGGATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAGATTTTACCTGGAAGTGGTAGTACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAAGATGGGGCGGGGGAATTTGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(2931.9) IGHD1-1*00(25) IGHJ2*00(395.2) nan 0|295|314|0|295||2950.0 21|26|69|305|310||25.0 28|68|68|312|352||400.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 GGCTACACATTCACTGGCTACTGG 45 ATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAG 45 ATTTTACCTGGAAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGATGGGGCGGGGGAATTTGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT GYTFTGYW IEWVKQRPGHGLEWIGE ILPGSGST NYNEKFKGKATFTADTSSNTAYMQLSSLTTEDSAIYY CARWGGGIWDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:305:2:-20:310:312:-8:321:352::
200 20 7.55607e-05 1 3.33422e-05 CGGGAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAATTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATCTATCCTGGAAATGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGCGGACTCTGCTGTCTATTTCTGTGCAAGAAACTACGGTAACTCGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2645.6) IGHD2-800(46),IGHD1-100(45) IGHJ3*00(500) IGHA*00(306.6) 0|294|314|0|291|SA1GDT4DC5DC6SC104TST152CSG163ASG213ASA265C|2652.0 20|32|51|292|304|ST24C|46.0;29|38|69|292|301||45.0 18|68|68|305|355||500.0 nan CGGGAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAATTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATCTATCCTGGAAATGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGCGGACTCTGCTGTCTATTTC 45 TGTGCAAGAAACTACGGTAACTCGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 RELKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGNGNT YYNEKFKGKATLTTEKSSSTAYMQLSSLTSADSAVYF CARNYGNSAWFAYW GQGTLVTVSA_ ::::0:72:96:147:171:282:0:291:292:-3:-2:304:305:2:324:355::
201 20 7.55607e-05 5 0.000166711 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTAAAGCCTGGGGCTTCAGTGAAGTTGTCCTGCAAGGCTTCTGGCTACACTTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAATGATTCATCCTAATAGTGGTAGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATTCCACCCCCCCGGTAGTAGCCCCCATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-64*00(2941.8) IGHD1-1*00(50) IGHJ4*00(536.6) IGHG2B*00(59.7) 0|295|314|0|295||2950.0 33|43|69|305|315||50.0 20|74|74|319|373||540.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTAAAGCCTGGGGCTTCAGTGAAGTTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAATG 45 ATTCATCCTAATAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATTCCACCCCCCCGGTAGTAGCCCCCATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGM IHPNSGST NYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYY CARFHPPGSSPHYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:1:295:305:-10:-3:315:319:0:342:373::
204 19 7.17826e-05 2 6.66844e-05 GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTCACTGACTACAACATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTAATTAATCCTAACTATGGTACTACTAGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAAAGGGGGGACCCTGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-39*00(2893.5) IGHD4-1*00(25) IGHJ3*00(405.7) IGHA*00(294.5) 0|292|314|0|292||2920.0 17|22|33|297|302||25.0 24|68|68|305|349||440.0 nan GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTCACTGACTACAAC 45 ATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTA 45 ATTAATCCTAACTATGGTACTACT 45 AGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAAAGGGGGGACCCTGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EFQLQQSGPELVKPGASVKISCKAS GYSFTDYN MNWVKQSNGKSLEWIGV INPNYGTT SYNQKFKGKATLTVDQSSSTAYMQLNSLTSEDSAVYY CAKGGTLFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:-2:292:297:-6:0:302:305:-4:318:349::
205 18 6.80046e-05 3 0.000100027 CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCTGGCTACGCATTCAGTAACTCCTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGGATTTATCCTGGAGATGGAGATACTAACTACAATGGGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTACTTCTGTGCAAGACGATGGTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-82*00(2903.4) IGHD2-3*00(25) IGHJ2*00(430) IGHA*00(80) 0|294|314|0|294|SG91A|2911.0 22|27|51|295|300||25.0 25|68|68|300|343||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCT 45 GGCTACGCATTCAGTAACTCCTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGG 45 ATTTATCCTGGAGATGGAGATACT 45 AACTACAATGGGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTACTTC 45 TGTGCAAGACGATGGTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYAFSNSW MNWVKQRPGKGLEWIGR IYPGDGDT NYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CARRWFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:295:-5:-7:300:300:-5:312:343::
206 18 6.80046e-05 2 6.66844e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTATTGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(345.2) IGHD5-700(58),IGHD5-800(58),IGHD6-2*00(58) IGHJ2*00(498.6) nan 0|92|321|0|92||920.0 3|17|87|140|155|I8A|58.0;3|17|87|140|155|I8A|58.0;3|17|87|140|155|I8A|58.0 15|68|68|188|241|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS nan nan nan nan nan GQGTTLTVSS_ ::::0:75:::::::140:26:-41:155:188:5:210:241::
207 17 6.42266e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACTTTCACTGTCTACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAATCCCTGGAGGGTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(371.6) IGHD5-800(53),IGHD5-700(52),IGHD6-1*00(52) IGHJ2*00(366.6) IGHG2C*00(67.4) 0|98|314|0|98|SA83TSG91T|922.0 10|33|87|62|83|DG15DG22ST26GSG30C|53.0;10|30|87|62|80|DG15DG22SC26G|52.0;10|30|87|62|80|DG15DG22SC26G|52.0 31|68|68|187|224||370.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 nan nan nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT nan nan nan nan nan GQGTTLTVSS_ ::::0:75:::::::62:19:-25:83:187:-11:193:224::
208 17 6.42266e-05 2 6.66844e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTATTGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(204.9) IGHD5-700(58),IGHD5-800(58),IGHD6-2*00(58) IGHJ2*00(501) nan 0|85|321|0|85||850.0 3|17|87|133|148|I8A|58.0;3|17|87|133|148|I8A|58.0;3|17|87|133|148|I8A|58.0 15|68|68|181|234|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS nan nan nan nan nan GQGTTLTVSS_ ::::0:75:::::::133:26:-41:148:181:5:203:234::
211 16 6.04485e-05 2 6.66844e-05 CAGTTAGACTTAAAGCACCACTGAGCCCAAGTCTTACACATCATGGATTGGGTGTGGACCTTGCTATTCCTGATGGCAGCTGCCCAAAAATATCCAATGCACTGGGTGAAGCAGGCTCCAGGAAAGGGTTTCAAGTGGATGGGCTGGATAAACACCTACTCTGGAGAGCCAACATATGCTGACGACTTCAAGGGACGGTTTGCCTTTTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGATTGGGCTACGGTAGTAGCTGGGGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-2*00(1319.2) IGHD3-100(40),IGHD1-100(35),IGHD3-2*00(35) IGHJ1*00(486.4) IGHG2C*00(64.5) 0|295|314|0|292|SA3TSC5ASC6GSG8CSC11ASG12AST13ASG17CST18CI19ASG22ASA23GST26CSG27AI30TSG32TSA34CSG35ASA36CSG38TSC40ASG45TSA46TSA48GSC49GSA50TSC53GDA54DA55ST58CDC61DC62SA66TSG68TSG69TDT71DT72ST76ASG77TST78GSA79GST80CSC82GST85GSA87CSG90AI93A|1383.0 27|35|51|293|301||40.0;30|37|69|296|303||35.0;26|33|48|294|301||35.0 15|73|73|303|361|SA22GSC23GST24G|493.0 nan CAGTTAGACTTAAAGCACCACTGAGCCCAAGTCTTACACATCATGGATTGGGTGTGGACCTTGCTATTCCT 45 GATGGCAGCTGCCCAAAAATATCCA 45 ATGCACTGGGTGAAGCAGGCTCCAGGAAAGGGTTTCAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGAGCCA 45 ACATATGCTGACGACTTCAAGGGACGGTTTGCCTTTTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCAAGATTGGGCTACGGTAGTAGCTGGGGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QLDLKHH*AQVL_HHGLGVDLAIP DGSC_QKYP MHWVKQAPGKGFKWMGW INTYSGEP TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CARLGYGSSWGYFDVW GTGTTVTVSS_ ::::0:71:96:147:171:282:1:292:293:-10:1:301:303:5:330:361::
212 16 6.04485e-05 4 0.000133369 CAGGTTCAGCTGCAGTAGTCTGGAGCTGAACTGGTGAAACCAGGGGCTTCAGTGAACCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAACTACATCATAAACTGGGTAAAGGAAGGGCCTGGACATGGCCTTGAGTGGATTGGATGGATTTCTCCTGAATATGGTCATACTTACTACAATCAGAGGTTCAAGGGCAAGGCCACATTCACTGCAGACACATCTTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACATCTGAGGACTCTGCAGTCTTTTTCTGTGCAAGTTGGTGGGACGCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-79*00(2803.1) IGHD4-1*00(30) IGHJ1*00(537.6) IGHG2B*00(60.9) 0|293|314|0|293|SG56CSA187GSC224TSA280T|2814.0 16|22|33|297|303||30.0 19|73|73|303|357||540.0 nan CAGGTTCAGCTGCAGTAGTCTGGAGCTGAACTGGTGAAACCAGGGGCTTCAGTGAACCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAACTACATC 45 ATAAACTGGGTAAAGGAAGGGCCTGGACATGGCCTTGAGTGGATTGGATGG 45 ATTTCTCCTGAATATGGTCATACT 45 TACTACAATCAGAGGTTCAAGGGCAAGGCCACATTCACTGCAGACACATCTTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACATCTGAGGACTCTGCAGTCTTTTTC 45 TGTGCAAGTTGGTGGGACGCTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQ*SGAELVKPGASVNLSCKAS GYTFTNYI INWVKEGPGHGLEWIGW ISPEYGHT YYNQRFKGKATFTADTSSSTAYMELSSLTSEDSAVFF CASWWDA_WYFDVW GTGTTVTVSS_ :::0:0:75:99:150:174:285:-1:293:297:-5:0:303:303:1:326:357::
214 15 5.66705e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAACACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAAGACTCTGCGGTCTATTATTGTTCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(1526.8),IGHV1-62-300(1497.8) IGHD4-1*00(45) IGHJ4*00(500) IGHA*00(308.8) 0|294|314|0|235|SC30TDC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123SG229ASG266ASG288T|1534.0;0|294|314|0|235|SC30TDA63DG64DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121SG229ASG266ASC284TSG288T|1505.0 14|23|33|241|250||45.0 24|74|74|252|302||500.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTG 45 nan 0 GACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAACACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAAGACTCTGCGGTCTATTAT 45 TGTTCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAEF_EAWGFSEAVL nan DEAL_WIGR IDPNSGGT KYNEKFKSKATLTVDKPSNTAYMQLSSLTSEDSAVYY CSRRGTGTLYAMDYW GQGTSVTVSS_ ::::0:65:65:91:115:226:0:235:241:-3:1:250:252:-4:271:302::
218 14 5.28925e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCTGGCTACGCATTCAGTAACTCCTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGGATTTATCCTGGAGATGGTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-82*00(1638.9) IGHD3-200(45),IGHD5-700(44),IGHD6-1*00(44) IGHJ2*00(427.9) IGHG2C*00(60) 0|167|314|0|167|SG91A|1641.0 4|13|48|24|33||45.0;10|34|87|62|84|DG15DA21SG22TSC26GSG30C|44.0;10|34|87|62|84|DG15DA21SG22TSC26GSG30C|44.0 25|68|68|167|210||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCT 45 GGCTACGCATTCAGTAACTCCTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGG 45 nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYAFSNSW MNWVKQRPGKGLEWIGR nan nan nan GQGTTLTVSS_ ::::0:75:99:150:::::24:12:-19:33:167:-5:179:210::
219 14 5.28925e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(266.4) IGHD1-1*00(85) IGHJ1*00(505.9) nan 0|85|321|0|85||850.0 23|40|69|170|187||85.0 22|73|73|189|240||510.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS nan nan nan nan nan GTGTTVTVSS_ ::::0:75:::::::170:0:-6:187:189:-2:209:240::
220 14 5.28925e-05 3 0.000100027 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAACTACTGGATGGATTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAATGGATTGGTAACATTTACCCTTCTGATAGTGAAACTCACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGGAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATCGGCTTACTATGATTACGACCTGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-61*00(2885.9) IGHD2-4*00(75) IGHJ3*00(437.6) nan 0|296|314|0|296|SG91ASC251G|2902.0 19|34|51|300|315||75.0 24|68|68|317|361||440.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAACTACTGG 45 ATGGATTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAATGGATTGGTAAC 45 ATTTACCCTTCTGATAGTGAAACT 45 CACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGGAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATCGGCTTACTATGATTACGACCTGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQPGAELVRPGSSVKLSCKAS GYTFTNYW MDWVKQRPGQGLEWIGN IYPSDSET HYNQKFKDKATLTVDKSSSTAYMQLRSLTSEDSAVYY CARSAYYDYDLFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:2:296:300:-2:0:315:317:-4:330:361::
224 13 4.91144e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACTTTCACTGTCTACTGGATAGAGTGGGTAAAGCAGAGGCCACCTTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAATCCCTGGAGGGTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(1214.2) IGHD5-800(53),IGHD5-700(52),IGHD6-1*00(52) IGHJ2*00(370) IGHG2C*00(65.8) 0|122|314|0|122|SA83TSG91T|1162.0 10|33|87|62|83|DG15DG22ST26GSG30C|53.0;10|30|87|62|80|DG15DG22SC26G|52.0;10|30|87|62|80|DG15DG22SC26G|52.0 31|68|68|221|258||370.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 GGCTACACTTTCACTGTCTACTGG 45 nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT GYTFTVYW nan nan nan nan GQGTTLTVSS_ ::::0:75:99::::::62:19:-25:83:221:-11:227:258::
225 13 4.91144e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACAATCTCCAAGGATACCTCCAAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(355.5) IGHD1-1*00(85) IGHJ1*00(510) nan 0|92|321|0|92||920.0 23|40|69|176|193||85.0 22|73|73|195|246||510.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS nan nan nan nan nan GTGTTVTVSS_ ::::0:75:::::::176:0:-6:193:195:-2:215:246::
226 13 4.91144e-05 1 3.33422e-05 CAGGTCCAGCTGAAGCAGTCTGGAGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATAAATTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAATGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGCGGACTCTGCTGTCTATTTCTGTGCAAGAAACTACGGTAACTCGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2634.3) IGHD2-800(46),IGHD1-100(45) IGHJ3*00(500) IGHA*00(310) 0|294|314|0|292|SG23ADT100DA101SC104TSG163ASG213ASA265C|2702.0 20|32|51|293|305|ST24C|46.0;29|38|69|293|302||45.0 18|68|68|306|356||500.0 nan CAGGTCCAGCTGAAGCAGTCTGGAGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 AAATTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAATGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTACAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGCGGACTCTGCTGTCTATTTC 45 TGTGCAAGAAACTACGGTAACTCGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY KLGEAEAW_QGLEWIAR IYPGNGNT YYNEKFKGKATLTTEKSSSTAYMQLSSLTSADSAVYF CARNYGNSAWFAYW GQGTLVTVSA_ ::::0:75:99:148:172:283:0:292:293:-3:-2:305:306:2:325:356::
227 13 4.91144e-05 2 6.66844e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGGACAAGGCCTTGAATGGATTGGTAACATTTACCCTTCTGATAGTGAAACTCACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAACTGGGACGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-61*00(1571) IGHD4-1*00(40) IGHJ2*00(458) nan 0|292|314|0|233|DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DG102DA103DT104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123|1630.0 15|23|33|233|241||40.0 22|68|68|241|287||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTG 45 nan 0 GACAAGGCCTTGAATGGATTGGTAAC 45 ATTTACCCTTCTGATAGTGAAACT 45 CACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAACTGGGACGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAEL_EAWVFSEAVL nan DKAL_WIGN IYPSDSET HYNQKFKDKATLTVDKSSSTAYMQLSSLTSEDSAVYY CATGTYFDYW GQGTTLTVSS_ ::::0:65:65:91:115:226:-2:233:233:-4:1:241:241:-2:256:287::
230 13 4.91144e-05 2 6.66844e-05 GAAGTGAAGCTTGAGGAGTCTGGAGGAGGCTTGGTGCAACCTGGAGGATCCATGAAACTCTCCTGTGTTGCCTCTGGATTCACTTTCAGTAACTACTGGATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTCAAATTAGATTGAAATCTGATAATTATGCAACACATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGGGCTGAAGACACTGGAATTTATTACTGCACATACTACGGTAGTAGTTCCCTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV6-3*00(2912.8) IGHD1-1*00(70) IGHJ3*00(420) IGHM*00(75.5) 0|297|319|0|297||2970.0 28|42|69|297|311||70.0 26|68|68|316|358||420.0 nan GAAGTGAAGCTTGAGGAGTCTGGAGGAGGCTTGGTGCAACCTGGAGGATCCATGAAACTCTCCTGTGTTGCCTCT 45 GGATTCACTTTCAGTAACTACTGG 45 ATGAACTGGGTCCGCCAGTCTCCAGAGAAGGGGCTTGAGTGGGTTGCTCAA 45 ATTAGATTGAAATCTGATAATTATGCAACA 45 CATTATGCGGAGTCTGTGAAAGGGAGGTTCACCATCTCAAGAGATGATTCCAAAAGTAGTGTCTACCTGCAAATGAACAACTTAAGGGCTGAAGACACTGGAATTTATTAC 45 TGCACATACTACGGTAGTAGTTCCCTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVKLEESGGGLVQPGGSMKLSCVAS GFTFSNYW MNWVRQSPEKGLEWVAQ IRLKSDNYAT HYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYY CTYYGSSSLAYW GQGTLVTVSA_ ::::0:75:99:150:180:291:-2:297:297:-5:-4:311:316:-6:327:358::
231 12 4.53364e-05 1 3.33422e-05 CAGTATCCTCTTCACAGTCACTGAAAACATTGACTCTAATCATGGAATGTAACTGGATACTTCCTTTTATTCTGTCGGTAACTTCAGGGGTCTACTCAGAGGCCTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATAGGGGCTATTTATCCTGGAAATAGTGATACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTACTGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-5*00(1195.6) IGHD3-2*00(60) IGHJ3*00(480) IGHG2B00(55),IGHG2C00(55) 0|294|314|0|293|SG0CSG3TST4ASA7CSG8TSC11TDG14ST20ASG21CSG22TSC25AST26ASG27AST28CSG29ASC30TSG33ASA35TI36CI36TSG37ASG38TSC40ASG44ASG45ASC46TST47GSC49ASG51CSA54GSG56TST58CSG59TSG64TSC65TSA66TDG68DA69DC70SG76TST78GSA79GSC80TSC82ASA83CST86CSC88GSC89GSA90GI92TSG97CSG98ASA99GST100ASC102GSA103C|1198.0 19|31|48|294|306||60.0 20|68|68|306|354||480.0 ; CAGTATCCTCTTCACAGTCACTGAAAACATTGACTCTAATCATGGAATGTAACTGGATACTTCCTTTTATTCT 45 GTCGGTAACTTCAGGGGTCTACTCA 45 GAGGCCTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATAGGGGCT 45 ATTTATCCTGGAAATAGTGATACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTAC 45 TGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QYPLHSHKHL_NHGM*LDTSFYS VGNF_GVYS EAWVKQRPGQGLEWIGA IYPGNSDT SYNQKFKGKAKLTAVTSASTAYMELSSLTNEDSAVYY CTRPAQATWFAYW GQGTLVTVSA_ ::::0:73:98:149:173:284:0:293:294:-3👎306:306:0:323:354::
232 12 4.53364e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACATTCACTGGCTACTGGATAGAGTGGGTAAAGCGAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAAGATGGGGGCTAACTGGTTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(1215.5) IGHD5-800(58),IGHD5-700(52),IGHD6-1*00(52) IGHJ2*00(427.4) IGHG2C*00(58.2) 0|115|314|0|115||1150.0 10|34|87|62|84|DG15DG22ST26GSG30C|58.0;10|30|87|62|80|DG15DG22SC26G|52.0;10|30|87|62|80|DG15DG22SC26G|52.0 25|68|68|226|269||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 GGCTACACATTCACTGGCTACTGG 45 nan nan nan nan nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT GYTFTGYW nan nan nan nan GQGTTLTVSS_ ::::0:75:99::::::62:19:-24:84:226:-5:238:269::
233 12 4.53364e-05 1 3.33422e-05 CAGGTTCAGCTGCAACAGTCTGACGCTGAGTTGGTGAAACCTGGAGCTTCAGTGAAGATATCCTGCAAGGTTTCTGGCTACACCTTCACTGACCATACTATTCACTGGATGAAGCAGAGGCCTGAACAGGGCCTGGAATGGATTGGATATATTTATCCTAGAGATGGTAGTACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTTCTGTGCAAAGGGATGGTTACTACCCTTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-78*00(2912.8) IGHD2-3*00(60) IGHJ4*00(500) nan 0|292|314|0|292||2920.0 22|34|51|295|307||60.0 24|74|74|311|361||500.0 nan CAGGTTCAGCTGCAACAGTCTGACGCTGAGTTGGTGAAACCTGGAGCTTCAGTGAAGATATCCTGCAAGGTTTCT 45 GGCTACACCTTCACTGACCATACT 45 ATTCACTGGATGAAGCAGAGGCCTGAACAGGGCCTGGAATGGATTGGATAT 45 ATTTATCCTAGAGATGGTAGTACT 45 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTTC 45 TGTGCAAAGGGATGGTTACTACCCTTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSDAELVKPGASVKISCKVS GYTFTDHT IHWMKQRPEQGLEWIGY IYPRDGST KYNEKFKGKATLTADKSSSTAYMQLNSLTSEDSAVYF CAKGWLLPFYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:-2:292:295:-5:0:307:311:-4:330:361::
234 12 4.53364e-05 1 3.33422e-05 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGATAAACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGACGGGGTACTACGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN9NNNNNNNNNNNNNNNNNNNN9ENNNNNNFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2652) IGHD1-1*00(75) IGHJ4*00(520) IGHA*00(306) 0|294|314|0|291|SG168TST169ADG170DC171DC172|2768.0 28|43|69|296|311||75.0 22|74|74|318|370||520.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 24 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 24 ATAAACACCTACTCTGGATAA 45 ACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 40 TGTGCAAGACGGGGTACTACGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSG* TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CARRGTTVVAARYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:171:282:0:291:296:-5:-3:311:318:-2:339:370::
235 12 4.53364e-05 1 3.33422e-05 CAAGTGCAGATGAAGGAGTCAGGACCTGACCTTGTGCAGCCATCACAGACTCTGTCTCTCACCTGCACTGTCTCTGGGTTCTCATTAAGTAGCTATGGTGTACATTGGTTTCGCAAGCCTCCGAGAAAGGGATTGGAATGGTTGGGAGGAATATGGTCTGGTGGAAGCATATACTATACTCCAGCTCTCAGTTCCCGACTGAGTGTCAGCAGGGACACCTCTAAGAGCCAAGTTTTCTTTAAAATGAGCAGTCTGCAAAGTGAAGACACGGCTGTGTACCACTGTGCCAGATATGGTAACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV2-7*00(2891.7) nan IGHJ4*00(500.3) IGHA*00(310) 0|294|313|0|294||2940.0 nan 23|74|74|298|349||510.0 nan CAAGTGCAGATGAAGGAGTCAGGACCTGACCTTGTGCAGCCATCACAGACTCTGTCTCTCACCTGCACTGTCTCT 45 GGGTTCTCATTAAGTAGCTATGGT 45 GTACATTGGTTTCGCAAGCCTCCGAGAAAGGGATTGGAATGGTTGGGAGGA 45 ATATGGTCTGGTGGAAGCATA 45 TACTATACTCCAGCTCTCAGTTCCCGACTGAGTGTCAGCAGGGACACCTCTAAGAGCCAAGTTTTCTTTAAAATGAGCAGTCTGCAAAGTGAAGACACGGCTGTGTACCAC 45 TGTGCCAGATATGGTAACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQMKESGPDLVQPSQTLSLTCTVS GFSLSSYG VHWFRKPPRKGLEWLGG IWSGGSI YYTPALSSRLSVSRDTSKSQVFFKMSSLQSEDTAVYH CARYGNYAMDYW GQGTSVTVSS_ ::::0:75:99:150:171:282:1:294:::::298:-3:318:349::
239 11 4.15584e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACCACTGGGCCTCTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2929.5) IGHD4-1*00(30) IGHJ2*00(437.4) IGHG2B00(54.5),IGHG2C00(54.5) 0|294|314|0|294||2940.0 14|20|33|296|302||30.0 24|68|68|305|349||440.0 ; CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACCACTGGGCCTCTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARPLGLFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:296:-3:-2:302:305:-4:318:349::
240 11 4.15584e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCCTCTGGCTACACCTTCACAAGCTATGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATTAGGAAGACTGGGCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(342.1) IGHD3-100(45),IGHD3-200(42) IGHJ1*00(540) IGHA*00(306.2) 0|97|314|0|97|ST71C|941.0 8|34|51|55|81|DG14SG17TSC21ASA22GI24CSG27T|45.0;27|41|48|125|139|SA30CST33C|42.0 19|73|73|187|241||540.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS nan nan nan nan nan GTGTTVTVSS_ ::::0:75:::::::55:9:0:81:187:1:210:241::
241 11 4.15584e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2921.5) IGHD1-1*00(85) IGHJ1*00(510) IGHA*00(310) 0|294|321|0|294||2940.0 23|40|69|294|311||85.0 22|73|73|313|364||510.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CAFITTVVDWYFDVW GTGTTVTVSS_ ::::0:75:105:156:177:288:-7:294:294:0:-6:311:313:-2:333:364::
242 11 4.15584e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTATTGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2844.7) IGHD4-1*00(35) IGHJ2*00(497.8) IGHA*00(310) 0|298|321|0|298|SC253GSC274TSC287TSC292T|2864.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCAGCAGTGTGGACACTGCAGATATTGCCACATACTAT 45 TGTGTTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKISSVDTADIATYY CVRTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
243 11 4.15584e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTAAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGTGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCCCCTATTACTACGGCGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-59*00(2871) IGHD1-1*00(55) IGHJ2*00(452.8) IGHA*00(310) 0|290|314|0|290||2900.0 25|36|69|293|304||55.0 22|68|68|306|352||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTAAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGTG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCCCCTATTACTACGGCGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVRPGTSVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGV IDPSDSYT NYNQKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYY CAPITTAYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:293:-2:-10:304:306:-2:321:352::
244 11 4.15584e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCAGTCCTGGACAAGGCCTTGAGTGGATTGGAAATATTAATCCTAGCAATGGTGGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGATTTTATTACTACGGTAGTAGCCTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-53*00(1610.3) IGHD1-1*00(85) IGHJ2*00(416.4) IGHA*00(310) 0|298|314|0|239|ST58ADC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123SC295T|1632.0 26|43|69|239|256||85.0 26|68|68|257|299||420.0 nan CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCAGTCCTG 45 nan 0 GACAAGGCCTTGAGTGGATTGGAAAT 45 ATTAATCCTAGCAATGGTGGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGATTTTATTACTACGGTAGTAGCCTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGTEL_EAWGFSEAVL nan DKAL_WIGN INPSNGGT NYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYY CARFYYYGSSLDYW GQGTTLTVSS_ ::::0:65:65:91:115:226:4:239:239:-3:-3:256:257:-6:268:299::
245 11 4.15584e-05 1 3.33422e-05 CAGGTGCAGCTGAAGGAGTCAGGACCTGGCCTGGTGGCGCCCTCACAGAGCCTGTCCATCACATGCACCGTCTCAGGGTTCTCATTAACCAGCTATGGTGTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGTAGTGATATGGAGTGATGGAAGCACAACCTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTCCAAACTGATGACACAGCCATGTACTACTGTGCCAGACAGGGTAGTAACTACGTGGGGGTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV2-6*00(2893.9) IGHD2-500(60),IGHD2-600(60),IGHD1-1*00(56) IGHJ3*00(414.6) IGHA*00(310) 0|291|311|0|291||2910.0 24|36|51|296|308||60.0;24|36|51|296|308||60.0;34|48|69|294|308|SG41A|56.0 23|68|68|310|355|ST25G|421.0 nan CAGGTGCAGCTGAAGGAGTCAGGACCTGGCCTGGTGGCGCCCTCACAGAGCCTGTCCATCACATGCACCGTCTCA 45 GGGTTCTCATTAACCAGCTATGGT 45 GTACACTGGGTTCGCCAGCCTCCAGGAAAGGGTCTGGAGTGGCTGGTAGTG 45 ATATGGAGTGATGGAAGCACA 45 ACCTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTCCAAACTGATGACACAGCCATGTACTAC 45 TGTGCCAGACAGGGTAGTAACTACGTGGGGGTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLKESGPGLVAPSQSLSITCTVS GFSLTSYG VHWVRQPPGKGLEWLVV IWSDGST TYNSALKSRLSISKDNSKSQVFLKMNSLQTDDTAMYY CARQGSNYVGVAYW GQGTLVTVSA_ ::::0:75:99:150:171:282:0:291:296:-7:2:308:310:-3:324:355::
246 11 4.15584e-05 1 3.33422e-05 GATCTACGGGTGGTGGAGTCTGGGGGAGACTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCAGTAGCTATGGCATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACCATTAGTGGTGGTGGTGGTTACACCTACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTACTGTGCAAGACGGGGCTCTACCTGGGACGGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-6*00(2737) IGHD4-100(31),IGHD5-500(30),IGHD1-1*00(28) IGHJ1*00(476.2) IGHA*00(310) 0|294|314|0|294|SG2TSG3CSG5ASA7GSC9GSA156GSA165G|2737.0 11|20|33|301|310|SA14C|31.0;12|18|30|301|307||30.0;3|12|69|298|306|DA6|28.0 22|73|73|310|361|ST24G|481.0 nan GATCTACGGGTGGTGGAGTCTGGGGGAGACTTAGTGAAGCCTGGAGGGTCCCTGAAACTCTCCTGTGCAGCCTCT 45 GGATTCACTTTCAGTAGCTATGGC 45 ATGTCTTGGGTTCGCCAGACTCCAGACAAGAGGCTGGAGTGGGTCGCAACC 45 ATTAGTGGTGGTGGTGGTTACACC 45 TACTATCCAGACAGTGTGAAGGGGCGATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCATGTATTAC 45 TGTGCAAGACGGGGCTCTACCTGGGACGGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 DLRVVESGGDLVKPGGSLKLSCAAS GFTFSSYG MSWVRQTPDKRLEWVAT ISGGGGYT YYPDSVKGRFTISRDNAKNTLYLQMSSLKSEDTAMYY CARRGSTWDGYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:301:0:-2:310:310:-2:330:361::
254 11 4.15584e-05 2 6.66844e-05 GAGGTTCAGCTCCAGCAGTCTGGGACTGTGCTGGCAAGGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGACTTCTGGCTACACATTTACCAGCTACTGGATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATAGGGGCTATTTATCCTGGAAATAGTGATACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTACTGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-5*00(2923.1) IGHD3-2*00(60) IGHJ3*00(420) IGHA*00(90.4) 0|294|314|0|294||2940.0 19|31|48|295|307||60.0 20|68|68|307|355||480.0 nan GAGGTTCAGCTCCAGCAGTCTGGGACTGTGCTGGCAAGGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGACTTCT 45 GGCTACACATTTACCAGCTACTGG 45 ATGCACTGGGTAAAACAGAGGCCTGGACAGGGTCTGGAATGGATAGGGGCT 45 ATTTATCCTGGAAATAGTGATACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTAC 45 TGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGTVLARPGASVKMSCKTS GYTFTSYW MHWVKQRPGQGLEWIGA IYPGNSDT SYNQKFKGKAKLTAVTSASTAYMELSSLTNEDSAVYY CTRPAQATWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:295:-3👎307:307:0:324:355::
255 11 4.15584e-05 2 6.66844e-05 GAAGTGAAGCTGGTGGAGTCTGAGGGAGGCTTAGTGCAGCCTGGAAGTTCCATGAAACTCTCCTGCACAGCCTCTGGATTCACTTTCAGTGACTATTACATGGCTTGGGTCCGCCAGGTTCCAGAAAAGGGTCTAGAATGGGTTGCAAACATTAATTATGATGGTAGTAGCACCTACTATCTGGACTCCTTGAAGAGCCGTTTCATCATCTCGAGAGACAATGCAAAGAACATTCTATACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCACGTATTACTGTGCAAGAAGGGTGGTCCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-16*00(2940) nan IGHJ1*00(510) IGHD*00(78.8) 0|294|314|0|294||2940.0 nan 22|73|73|304|355||510.0 nan GAAGTGAAGCTGGTGGAGTCTGAGGGAGGCTTAGTGCAGCCTGGAAGTTCCATGAAACTCTCCTGCACAGCCTCT 45 GGATTCACTTTCAGTGACTATTAC 45 ATGGCTTGGGTCCGCCAGGTTCCAGAAAAGGGTCTAGAATGGGTTGCAAAC 45 ATTAATTATGATGGTAGTAGCACC 45 TACTATCTGGACTCCTTGAAGAGCCGTTTCATCATCTCGAGAGACAATGCAAAGAACATTCTATACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCACGTATTAC 45 TGTGCAAGAAGGGTGGTCCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVKLVESEGGLVQPGSSMKLSCTAS GFTFSDYY MAWVRQVPEKGLEWVAN INYDGSST YYLDSLKSRFIISRDNAKNILYLQMSSLKSEDTATYY CARRVVHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:::::304:-2:324:355::
256 10 3.77803e-05 1 3.33422e-05 CAGGTTCAGCTGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCCTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATTAGGAAGACTGGGCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2753.1) IGHD4-100(25),IGHD6-200(25) IGHJ1*00(540) IGHA*00(304) 0|295|314|0|292|DC15DA16DG17ST71C|2807.0 14|19|33|299|304||25.0;16|21|87|297|302||25.0 19|73|73|304|358||540.0 nan CAGGTTCAGCTGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCCTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATTAGGAAGACTGGGCTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARLGRLGYWYFDVW GTGTTVTVSS_ ::::0:72:96:147:171:282:1:292:299:-3:-3:304:304:1:327:358::
257 10 3.77803e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATGGGATTACTACGGTAGTAGCTACGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2937.6) IGHD1-1*00(100) IGHJ2*00(400) nan 0|295|314|0|295||2950.0 26|46|69|298|318||100.0 28|68|68|318|358||400.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATGGGATTACTACGGTAGTAGCTACGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARWDYYGSSYDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:298:-3:0:318:318:-8:327:358::
258 10 3.77803e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTCAAGGCTACTGGCTACACATGGCCTTGAGTGGATTGGAGAGATTTTACCTGGAAGTGGTAGTACTAACTACAATGAGAAGTTCAAGGGCGAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAAGATGGGGGCTAACTGGTTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(1867.6) IGHD4-1*00(45) IGHJ2*00(430) IGHG2C*00(62.8) 0|295|314|0|250|DG64DT85DC86DA87DC88DT89DG90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DA101DG102DA103DG104DT105DG106DG107DG108DT109DA110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123DG124DA125DC126DA127DT128SA198G|1874.0 10|19|33|254|263||45.0 25|68|68|264|307||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTCAAGGCTACT 45 GGCTACACAT 45 GGCCTTGAGTGGATTGGAGAG 45 ATTTTACCTGGAAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGGGCGAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGATGGGGGCTAACTGGTTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELM_AWGLSEAFLKAT GY_H GLEWIGE ILPGSGST NYNEKFKGEATFTADTSSNTAYMQLSSLTTEDSAIYY CARWGLTGFDYW GQGTTLTVSS_ ::::0:74:84:105:129:240:1:250:254:1:-3:263:264:-5:276:307::
259 10 3.77803e-05 2 6.66844e-05 CAGGTTCAGCTGCAACAGTCTGACGCTGAGTTGGTGAAACCTGGAGCTTCAGTGAAGATATCCTGCAAGGTTTCTGGCTACACCTTCACTGACCATACTATTCACTGGATGAAGCAGAGGCCTGAACAGGGCCTGGAATGGATTGGATATATTTATCCTAGAGATGGTAGTACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTTCTGTGCAAGGGGTAGTAGTCCTTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-78*00(2926.4) IGHD1-100(40),IGHD2-500(36),IGHD2-6*00(36) IGHJ2*00(490) nan 0|293|314|0|293||2930.0 34|42|69|294|302||40.0;10|20|51|296|306|SG16T|36.0;10|20|51|296|306|SG16T|36.0 19|68|68|306|355||490.0 nan CAGGTTCAGCTGCAACAGTCTGACGCTGAGTTGGTGAAACCTGGAGCTTCAGTGAAGATATCCTGCAAGGTTTCT 45 GGCTACACCTTCACTGACCATACT 45 ATTCACTGGATGAAGCAGAGGCCTGAACAGGGCCTGGAATGGATTGGATAT 45 ATTTATCCTAGAGATGGTAGTACT 45 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACATTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTTC 45 TGTGCAAGGGGTAGTAGTCCTTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSDAELVKPGASVKISCKVS GYTFTDHT IHWMKQRPEQGLEWIGY IYPRDGST KYNEKFKGKATLTADKSSSTAYMQLNSLTSEDSAVYF CARGSSPYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285👎293:294:-11:-4:302:306:1:324:355::
260 10 3.77803e-05 1 3.33422e-05 CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACAGCTTCACAAGCTACTATATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGGATTTATCCTGGAAGTGGTAATACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATGTCTACTATGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-66*00(2884.2) IGHD2-700(50),IGHD2-800(50),IGHD2-4*00(45) IGHJ4*00(516) IGHA*00(62) 0|295|314|0|295||2950.0 17|27|51|296|306||50.0;17|27|51|296|306||50.0;17|26|51|296|305||45.0 22|74|74|306|358||520.0 nan CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACAGCTTCACAAGCTACTAT 45 ATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGG 45 ATTTATCCTGGAAGTGGTAATACT 45 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATGTCTACTATGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYSFTSYY IHWVKQRPGQGLEWIGW IYPGSGNT KYNEKFKGKATLTADTSSSTAYMQLSSLTSEDSAVYY CARCLLWYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:1:295:296:0:-7:306:306:-2:327:358::
261 10 3.77803e-05 1 3.33422e-05 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAACTGGGTGAAGCAGTCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2821.4) IGHD2-800(60),IGHD2-700(55) IGHJ2*00(446.9) IGHG2C*00(65) 0|296|314|0|294|SA117TDG118DG119|2838.0 17|29|51|296|308||60.0;17|28|51|296|307||55.0 20|68|68|308|356|ST25G|451.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGTCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTC 45 TGTGCAAGATCGGTCTACTATGGTAACTACGTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQSW_QGLEWIAR IYPGSGNT YYNEKFKGKATLTAEKSSSTAYMQLSSLTSEDSAVYF CARSVYYGNYVDYW GQGTTLTVSS_ ::::0:75:99:148:172:283:2:294:296:0:-5:308:308:0:325:356::
262 10 3.77803e-05 1 3.33422e-05 CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACTTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGGATTTATCCTGGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTCTGTGCAAGATGCTATGGTAACTACTTGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-76*00(2950) IGHD2-8*00(65) IGHJ2*00(500) nan 0|295|314|0|295||2950.0 21|34|51|296|309||65.0 18|68|68|311|361||500.0 nan CAGGTCCAGCTGAAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACTTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGCAAGG 45 ATTTATCCTGGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGAAAAATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCTGTCTATTTC 45 TGTGCAAGATGCTATGGTAACTACTTGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLKQSGAELVRPGASVKLSCKAS GYTFTDYY INWVKQRPGQGLEWIAR IYPGSGNT YYNEKFKGKATLTAEKSSSTAYMQLSSLTSEDSAVYF CARCYGNYLYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:296:-4:0:309:311:2:330:361::
263 10 3.77803e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGATCCTACGGTAGTCCTTATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2921.3),IGHV1-62-300(2863.3) IGHD1-1*00(50) IGHJ4*00(550) IGHD*00(79.2) 0|296|314|0|296||2960.0;0|296|314|0|296|SA63TSC284T|2902.0 30|40|69|296|306||50.0 19|74|74|309|364||550.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGATCCTACGGTAGTCCTTATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARSYGSPYYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:2:296:296:-7:-6:306:309:1:333:364::
264 10 3.77803e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGGACAAGGCCTTGAGTGGATCGGAGTGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCCCCTATTACTACGGCGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-59*00(1540.4) IGHD1-1*00(55) IGHJ2*00(454.2) nan 0|290|314|0|231|DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DA110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123|1610.0 25|36|69|234|245||55.0 22|68|68|247|293||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTG 45 nan 0 GACAAGGCCTTGAGTGGATCGGAGTG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCCCCTATTACTACGGCGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAEL_EAWDFSEVVL nan DKAL_WIGV IDPSDSYT NYNQKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYY CAPITTAYFDYW GQGTTLTVSS_ ::::0:65:65:91:115:226:-4:231:234:-2:-10:245:247:-2:262:293::
265 10 3.77803e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGGTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGCCAAGGCCTTGAGTGGATTGGAAGGATTCATCCTTCTGATAGTGATACTAACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAATCTACTACGGTAGTAGCTACGATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-74*00(2920.1) IGHD1-1*00(65) IGHJ4*00(491) nan 0|296|314|0|296|SA293C|2931.0 30|43|69|296|309||65.0 22|74|74|309|361|ST25G|491.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGGTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGCCAAGGCCTTGAGTGGATTGGAAGG 45 ATTCATCCTTCTGATAGTGATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAATCTACTACGGTAGTAGCTACGATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKVSCKAS GYTFTSYW MHWVKQRPGQGLEWIGR IHPSDSDT NYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYY CAIYYGSSYDAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:2:296:296:-7:-3:309:309:-2:330:361::
267 10 3.77803e-05 1 3.33422e-05 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATTCTGTGCTCATTACGACGGCTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2782.6) IGHD5-700(51),IGHD5-800(51),IGHD6-2*00(51) IGHJ2*00(470) IGHA*00(307.2) 0|280|314|0|280||2800.0 40|53|87|161|174|SC45G|51.0;40|53|87|161|174|SC45G|51.0;40|53|87|161|174|SC45G|51.0 21|68|68|299|346||470.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSGVP nan nan GQGTTLTVSS_ ::::0:75:99:150:174::::161:-11:-5:174:299:-1:315:346::
275 9 3.40023e-05 1 3.33422e-05 CAGGTTCAGCTGCAGTAGTCTGGAGCTGAACTGGTGAAACCAGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAACTACATCATAAACTGGGTAAAGGAAGGGCCTGGACATGGCCTTGAGTGGATTGGATGGATTTCTCCTGAATATGGTCATACTTACTACAATCAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGACACATCCTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTTCTGTGCAAGTTGGTGGGACGCTACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-79*00(2909.3) IGHD4-1*00(30) IGHJ1*00(531.7) nan 0|293|314|0|293||2930.0 16|22|33|297|303||30.0 19|73|73|303|357||540.0 nan CAGGTTCAGCTGCAGTAGTCTGGAGCTGAACTGGTGAAACCAGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAACTACATC 45 ATAAACTGGGTAAAGGAAGGGCCTGGACATGGCCTTGAGTGGATTGGATGG 45 ATTTCTCCTGAATATGGTCATACT 45 TACTACAATCAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGACACATCCTCCAGCACAGCCTACATGGAGCTCAGCAGCCTGACATCTGAGGACTCTGCAGTCTATTTC 45 TGTGCAAGTTGGTGGGACGCTACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQ*SGAELVKPGASVKLSCKAS GYTFTNYI INWVKEGPGHGLEWIGW ISPEYGHT YYNQKFKGKATFTADTSSSTAYMELSSLTSEDSAVYF CASWWDA_WYFDVW GTGTTVTVSS_ :::0:0:75:99:150:174:285:-1:293:297:-5:0:303:303:1:326:357::
276 9 3.40023e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCTGGCTACGCATTCAGTAACTCCTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGGATTTATCCTGGAGATGGAGATACTAACTACAATGGGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTACTTCTGTGCAAGACGATGGTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-82*00(2901.3) IGHD2-3*00(25) IGHJ2*00(430) nan 0|294|314|0|294|SG91A|2911.0 22|27|51|295|300||25.0 25|68|68|300|343||430.0 nan CAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAGGCTTCT 45 GGCTACGCATTCAGTAACTCCTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACGG 45 ATTTATCCTGGAGATGGAGATACT 45 AACTACAATGGGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAACTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTACTTC 45 TGTGCAAGACGATGGTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYAFSNSW MNWVKQRPGKGLEWIGR IYPGDGDT NYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CARRWFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:295:-5:-7:300:300:-5:312:343::
277 9 3.40023e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCTATTACTACGGTAGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2858.1) IGHD1-1*00(65) IGHJ2*00(396.8) nan 0|290|314|0|290||2900.0 25|38|69|290|303||65.0 28|68|68|303|343||400.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCTATTACTACGGTAGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CAITTVDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:290:-2:-8:303:303:-8:312:343::
278 9 3.40023e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2896.5) IGHD1-1*00(85) IGHJ1*00(510) IGHM*00(71) 0|294|321|0|294||2940.0 23|40|69|294|311||85.0 22|73|73|313|364||510.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTTTTATTACTACGGTAGTTGACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CAFITTVVDWYFDVW GTGTTVTVSS_ ::::0:75:105:156:177:288:-7:294:294:0:-6:311:313:-2:333:364::
279 9 3.40023e-05 2 6.66844e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2974.2) IGHD4-1*00(35) IGHJ2*00(501) IGHG2B00(55),IGHG2C00(55) 0|298|321|0|298||2980.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 ; CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
280 9 3.40023e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCCCTTATTACTACGGCACCCCCGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-69*00(2865.1) IGHD1-1*00(60) IGHJ3*00(447.5) IGHA*00(282) 0|290|314|0|290||2900.0 24|36|69|292|304||60.0 24|68|68|311|355||440.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCCCTTATTACTACGGCACCCCCGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQPGAELVMPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGE IDPSDSYT NYNQKFKGKSTLTVDKSSSTAYMQLSSLTSEDSAVYY CALITTAPPFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:-4:290:292:-1:-10:304:311:-4:324:355::
281 9 3.40023e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGAGACTGGGACAACCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-69*00(2901.4) IGHD4-1*00(40) IGHJ1*00(513.8) IGHA*00(310) 0|294|314|0|294||2940.0 14|22|33|295|303||40.0 22|73|73|307|358||510.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGATGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGAG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGTCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGAGACTGGGACAACCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQPGAELVMPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGE IDPSDSYT NYNQKFKGKSTLTVDKSSSTAYMQLSSLTSEDSAVYY CARDWDNHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:295:-3:0:303:307:-2:327:358::
282 9 3.40023e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGTAAGGCCACACTGACTGTAGACAAACCCTCCAGTACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNNNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2864.6),IGHV1-62-300(2806.6) IGHD4-1*00(45) IGHJ4*00(303) IGHA*00(307.2) 0|294|314|0|294|SC197TSC230T|2882.0;0|294|314|0|294|SA63TSC197TSC230TSC284T|2824.0 14|23|33|300|309||45.0 24|74|74|311|358|DA35DC36DT37|386.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGTAAGGCCACACTGACTGTAGACAAACCCTCCAGTACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGGACTGGGACGCTCTATGCTATGGACTGG 42 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGTGTLYAMDW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:300:-3:1:309:311:-4:327:358::
283 9 3.40023e-05 1 3.33422e-05 CAGGCTTATCTACAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCCTCAGTGAAGATGTCCTGCAAGGCTTCTGGCTACACATTTACCAGTTACAATATGCACTGGGTAAAGCAGACACCTAGACAGGGCCTGGAATGGATTGGAGCTATTTATCCAGGAAATGGTGATACTTCCTACAATCAGAAGTTCAAGGGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAAGACTCTGCGGTCTATTTCTGTGCAAGATCCACCCTTTATTACTACGGTAGTAGCTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-12*00(2954.2) IGHD1-1*00(95) IGHJ1*00(500) nan 0|296|314|0|296||2960.0 23|42|69|301|320||95.0 23|73|73|320|370||500.0 nan CAGGCTTATCTACAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCCTCAGTGAAGATGTCCTGCAAGGCTTCT 45 GGCTACACATTTACCAGTTACAAT 45 ATGCACTGGGTAAAGCAGACACCTAGACAGGGCCTGGAATGGATTGGAGCT 45 ATTTATCCAGGAAATGGTGATACT 45 TCCTACAATCAGAAGTTCAAGGGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAAGACTCTGCGGTCTATTTC 45 TGTGCAAGATCCACCCTTTATTACTACGGTAGTAGCTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QAYLQQSGAELVRPGASVKMSCKAS GYTFTSYN MHWVKQTPRQGLEWIGA IYPGNGDT SYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYF CARSTLYYYGSSWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:2:296:301:0:-4:320:320:-3:339:370::
290 9 3.40023e-05 1 3.33422e-05 GAGGTTCAGCTCCAGCAGTCTGGGACTGTGCTGGCAAGGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGACTTCTAGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTACTGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-5*00(740.3) IGHD3-2*00(60) IGHJ3*00(473.6) IGHG2C*00(62.8) 0|294|314|0|195|DG75DG76DC77DT78DA79DC80DA81DC82DA83DT84DT85DT86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DA110DA111DA112DA113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123DG124DA125DC126DA127DG128DG129DG130DT131DC132DT133DG134DG135DA136DA137DT138DG139DG140DA141DT142DA143DG144DG145DG146DG147DC148DT149DA150DT151DT152DT153DA154DT155DC156DC157DT158DG159DG160DA161DA162DA163DT164DA165DG166DT167DG168DA169DT170DA171DC172DT173|810.0 19|31|48|196|208||60.0 20|68|68|208|256||480.0 nan GAGGTTCAGCTCCAGCAGTCTGGGACTGTGCTGGCAAGGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGACTTCT 43 nan 0 nan 0 nan 0 AGCTACAACCAGAAGTTCAAGGGCAAGGCCAAACTGACTGCAGTCACATCCGCCAGCACTGCCTACATGGAGCTCAGCAGCCTGACAAATGAGGACTCTGCGGTCTATTAC 45 TGTACAAGACCAGCTCAGGCTACCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGTVLARPGASVKMSCKTS nan nan nan SYNQKFKGKAKLTAVTSASTAYMELSSLTNEDSAVYY CTRPAQATWFAYW GQGTLVTVSA_ ::::0:75:75:75:75:186:0:195:196:-3👎208:208:0:225:256::
291 9 3.40023e-05 1 3.33422e-05 GAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTCGTGAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTCACTAGCTACTAAATGCACTGGGTGAAGCAAAGCCATGGAAAGAGCCTTGAGTGGATTGGACTTATTATTCCTTACAATGGTGATACTGGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACTAGTCCTTCAGCACAACCTACATGGAGCTCCGCAGCCTGAAATCTGAGGACTCTGCGGTCTATTACTCTACCTCTATGGTAAACCCTCGTCTACTGACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN7NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-38*00(2856.2) IGHD2-8*00(45) IGHJ2*00(450) IGHA*00(307.7) 0|289|313|0|289||2890.0 21|30|51|291|300||45.0 23|68|68|314|359||450.0 nan GAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTCGTGAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTCACTAGCTACTAA 45 ATGCACTGGGTGAAGCAAAGCCATGGAAAGAGCCTTGAGTGGATTGGACTT 45 ATTATTCCTTACAATGGTGATACT 45 GGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACTAGTCCTTCAGCACAACCTACATGGAGCTCCGCAGCCTGAAATCTGAGGACTCTGCGGTCTATTAC 45 TCTACCTCTATGGTAAACCCTCGTCTACTGACTTTGACTACTGG 22 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELV_PGASVKISCKAS GYSFTSY* MHWVKQSHGKSLEWIGL IIPYNGDT GYNQKFKGKATLTVD*SFSTTYMELRSLKSEDSAVYY STSMVNP_STDFDYW GQGTTLTVSS_ :::0:0:74:98:149:173:284:-4:289:291:-4:-4:300:314:-3:328:359::
292 9 3.40023e-05 1 3.33422e-05 GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCAGGGTTCACTTTTAGTGGCTTCTGGATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGACATTAATTCTGATGGCAGTGCAATAAACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTCTGTATGAGGGGAACTGGCTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV11-2*00(2921.7) IGHD4-1*00(30) IGHJ1*00(495.9) IGHM*00(85) 0|293|316|0|293||2930.0 13|19|33|296|302||30.0 23|73|73|302|352||500.0 nan GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCA 45 GGGTTCACTTTTAGTGGCTTCTGG 45 ATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGAC 45 ATTAATTCTGATGGCAGTGCAATA 45 AACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTC 45 TGTATGAGGGGAACTGGCTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLLETGGGLVQPGGSRGLSCEGS GFTFSGFW MSWVRQTPGKTLEWIGD INSDGSAI NYAPSIKDRFTIFRDNDKSTLYLQMSNVRSEDTATYF CMRGTGWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:-3:293:296:-2:-3:302:302:-3:321:352::
294 8 3.02243e-05 1 3.33422e-05 TACGGGACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTTTGGTATGGGTGTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACACATTTGGTGGGATGATGATAAGTACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-8*00(2864.3) IGHD2-4*00(70) IGHJ3*00(490.3) IGHG2C*00(66.7) 0|299|321|0|299|SC0TSG2CST4GST5G|2874.0 20|34|51|301|315||70.0 18|68|68|317|367||500.0 nan TACGGGACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTTTGGTATGGGT 45 GTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTGGTGGGATGATGATAAG 45 TACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 YGTLKESGPGILQPSQTLSLTCSFS GFSLSTFGMG VGWIRQPSGKGLEWLAH IWWDDDK YYNPALKSRLTISKDTSKNQVFLKIANVDTADTATYY CARMDYDYDRAWFAYW GQGTLVTVSA_ ::::0:75:105:156:177:288:-2:299:301:-3:0:315:317:2:336:367::
295 8 3.02243e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGTTCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATTCTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGGGGGACAGGGGGACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2847.2) IGHD3-200(25),IGHD4-100(25),IGHD5-8*00(25) IGHJ2*00(450) IGHA*00(310) 0|294|314|0|294|SA28TSG29TSA171T|2853.0 17|22|48|298|303||25.0;17|22|33|296|301||25.0;30|35|87|298|303||25.0 23|68|68|307|352||450.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGTTCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATTCT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGGGGGACAGGGGGACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAVLARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNS YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARGGQGDFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:298:-1:-10:303:307:-3:321:352::
296 8 3.02243e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGGGGTGATGGTTACTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2915.5) IGHD2-3*00(45) IGHJ3*00(470) nan 0|293|314|0|293||2930.0 21|30|51|296|305||45.0 21|68|68|305|352||470.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGGGGTGATGGTTACTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARGDGYWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285👎293:296:-4:-4:305:305:-1:321:352::
297 8 3.02243e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGGGGAGGGACTGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2935.2) IGHD4-1*00(25) IGHJ2*00(320) nan 0|294|314|0|294||2940.0 17|22|33|299|304||25.0 36|68|68|305|337||320.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGGGGAGGGACTG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARGEGL GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:299:-6:0:304:305:-16:306:337::
298 8 3.02243e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGGAAGATCGGTAACTACGGATATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(305) IGHD6-200(64),IGHD5-700(58),IGHD5-8*00(58) IGHJ4*00(556.4) IGHG2C*00(65) 0|85|321|0|85||850.0 3|21|87|133|152|I8ASG17T|64.0;3|17|87|133|148|I8A|58.0;3|17|87|133|148|I8A|58.0 18|74|74|190|246||560.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS nan nan nan nan nan GQGTSVTVSS_ ::::0:75:::::::133:26:-37:152:190:2:215:246::
304 8 3.02243e-05 1 3.33422e-05 GAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTTAACATTAAAGACGACTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGGATTGATCCTGAGAATGGTGATACTGAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTACTACCCTAGACAGCTCAGGCTACGATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-4*00(2889) IGHD3-2*00(75) IGHJ4*00(486.2) IGHD*00(80) 0|293|314|0|293||2930.0 14|29|48|294|309||75.0 22|74|74|309|361|ST25G|491.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 42 GGCTTTAACATTAAAGACGACTAT 45 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGG 45 ATTGATCCTGAGAATGGTGATACT 45 GAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTACTACCCTAGACAGCTCAGGCTACGATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 EVQLQQSGAELVRPGASVKLSCTAS GFNIKDDY MHWVKQRPEQGLEWIGW IDPENGDT EYASKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CTTLDSSGYDAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285👎293:294:2:-3:309:309:-2:330:361::
305 8 3.02243e-05 1 3.33422e-05 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCGGCGAGGAGGGGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2895.2) nan IGHJ2*00(400) IGHA*00(62) 0|290|314|0|290||2900.0 nan 28|68|68|303|343||400.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCGGCGAGGAGGGGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CAARRGDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:::::303:-8:312:343::
306 8 3.02243e-05 1 3.33422e-05 GAGGTCCAGCTGCAACAATCTGGACCGGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGATGAAACAGAGCCATGGACAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATAGAACTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCGGCGAGGAGGGGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2705) nan IGHJ2*00(400) IGHA*00(101) 0|290|314|0|290|ST26GSG108ASG113ASA126CSG242ASG245A|2726.0 nan 28|68|68|303|343||400.0 nan GAGGTCCAGCTGCAACAATCTGGACCGGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGATGAAACAGAGCCATGGACAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATAGAACTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCGGCGAGGAGGGGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWMKQSHGQSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYIELRSLTSEDSAVYY CAARRGDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:::::303:-8:312:343::
310 7 2.64462e-05 1 3.33422e-05 CAGGTTCAACTGCAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGACGCTGTCCTGCAAGGCTTCGGGCTACACATTTACTGACTATGAAATGCACTGGGTGAAGCAGACACCTGTGCATGGCCTGGAATGGATTGGAGCTATTGATCCTGAAACTGGTGGTACTGCCTACAATCAGAAGTTCAAGGGCAAGGCCATACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCCGTCTATTACTGTACAAGACAGGTGGGACGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-15*00(2940) IGHD4-1*00(35) IGHJ3*00(500) nan 0|294|314|0|294||2940.0 16|23|33|298|305||35.0 18|68|68|305|355||500.0 nan CAGGTTCAACTGCAGCAGTCTGGGGCTGAGCTGGTGAGGCCTGGGGCTTCAGTGACGCTGTCCTGCAAGGCTTCG 45 GGCTACACATTTACTGACTATGAA 45 ATGCACTGGGTGAAGCAGACACCTGTGCATGGCCTGGAATGGATTGGAGCT 45 ATTGATCCTGAAACTGGTGGTACT 45 GCCTACAATCAGAAGTTCAAGGGCAAGGCCATACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCCGTCTATTAC 45 TGTACAAGACAGGTGGGACGGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQSGAELVRPGASVTLSCKAS GYTFTDYE MHWVKQTPVHGLEWIGA IDPETGGT AYNQKFKGKAILTADKSSSTAYMELRSLTSEDSAVYY CTRQVGRAWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:298:-5:1:305:305:2:324:355::
311 7 2.64462e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-8*00(809.7) IGHD2-400(70),IGHD6-200(64) IGHJ3*00(500) IGHG2C*00(65) 0|85|321|0|85||850.0 20|34|51|200|214||70.0;3|21|87|156|175|I8ASG17T|64.0 18|68|68|216|266||500.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 nan nan nan nan nan nan nan nan nan nan GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVTLKESGPGILQPSQTLSLTCSFS nan nan nan nan nan GQGTLVTVSA_ ::::0:75:::::::200:-3:0:214:216:2:235:266::
312 7 2.64462e-05 1 3.33422e-05 CAGGTCCAATTGCAGCAGCCTGGGGCTGAGTTTGTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-72*00(731) IGHD2-8*00(50) IGHJ4*00(500) IGHG2C*00(70) 0|294|314|0|194|SC9TSC30TDA37DG38DC39DC40DT41DG42DG43DG44DG45DC46DT47DT48DC49DA50DG51DT52DG53DA54DA55DG56DC57DT58DG59DT60DC61DC62DT63DG64DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123DG124DA125DC126DG127DA128DG129DG130DC131DC132DT133DT134DG135DA136|731.0 21|31|51|199|209||50.0 24|74|74|211|261||500.0 nan CAGGTCCAATTGCAGCAGCCTGGGGCTGAGTTTGTGA 45 nan 0 GTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQ_LGLSL* nan VD_GR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGYGNLYAMDYW GQGTSVTVSS_ ::::0:37:37:50:74:185:0:194:199:-4:-3:209:211:-4:230:261::
326 7 2.64462e-05 1 3.33422e-05 GAGCCCAAGTCTTAGACATCATGGGTTGGCTGTGGAACTTGCTATTCCTGATGGCAGCTGCCCAAAGTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACGTATGCTGATGACTTCAAGGGACGGTTTACCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAAGACACGGCTACATATTTCTGTGCAAGACGGGGTACTGCGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(1643) IGHD1-1*00(61) IGHJ4*00(515.9) IGHA*00(308) 0|294|314|0|298|SC0GSA3CST4CSC6AI10CSG11TSG12AST13GSG17TST18CSC19ASA23GDC24DC25SG27TSA28GSA33TSA34GDG38DC39SG42TSA44CSG45TSG47TSA48TI50CI50TI50GSG51TST52GSC53GSA54CSA57CSC59GST60CI63AI63AI63AI63GSA176GSG204ASG266A|1643.0 28|43|69|303|318|SA32G|61.0 22|74|74|325|377||520.0 nan GAGCCCAAGTCTTAGACATCATGGGTTGGCTGTGGAACTTGCTATTCCTGATGGCAGCTGCCCAAAGTGCAAGGCTTCT 45 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 45 ATAAACACCTACTCTGGAGTGCCA 45 ACGTATGCTGATGACTTCAAGGGACGGTTTACCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAAGACACGGCTACATATTTC 45 TGTGCAAGACGGGGTACTGCGGTAGTAGCGGCGAGGTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 EPKS*TSWVGCGT_AIPDGSCPKCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSGVP TYADDFKGRFTFSLETSASTAYLQINNLKNEDTATYF CARRGTAVVAARYYAMDYW GQGTSVTVSS_ ::::0:79:103:154:178:289:0:298:303:-5:-3:318:325:-2:346:377::
327 7 2.64462e-05 1 3.33422e-05 GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCAGGGTTCACTTTTAGTGGCTTCTGGATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGACATTAATTCTGATGGCAGTGCAATAAACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTCTGTATGAGGGGAACTGGCTGGTACTTCGATGTCTGGGGCACAGGAACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV11-2*00(2931.8) IGHD4-1*00(30) IGHJ1*00(482.7) IGHM*00(85) 0|293|316|0|293||2930.0 13|19|33|296|302||30.0 23|73|73|302|352|SG50A|471.0 nan GAAGTGCAGCTGTTGGAGACTGGAGGAGGCTTGGTGCAACCTGGGGGGTCACGGGGACTCTCTTGTGAAGGCTCA 45 GGGTTCACTTTTAGTGGCTTCTGG 45 ATGAGCTGGGTTCGACAGACACCTGGGAAGACCCTGGAGTGGATTGGAGAC 45 ATTAATTCTGATGGCAGTGCAATA 45 AACTACGCACCATCCATAAAGGATCGATTCACTATCTTCAGAGACAATGACAAGAGCACCCTGTACCTGCAGATGAGCAATGTGCGATCGGAGGACACAGCCACGTATTTC 45 TGTATGAGGGGAACTGGCTGGTACTTCGATGTCTGG 45 GGCACAGGAACCACGGTCACCGTCTCCTCAG 45 EVQLLETGGGLVQPGGSRGLSCEGS GFTFSGFW MSWVRQTPGKTLEWIGD INSDGSAI NYAPSIKDRFTIFRDNDKSTLYLQMSNVRSEDTATYF CMRGTGWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:-3:293:296:-2:-3:302:302:-3:321:352::
329 7 2.64462e-05 1 3.33422e-05 ACGGGGACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTTTGGTATGGGTGTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACACATTTGGTGGGATGATGATAAGTACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-8*00(2874) IGHD2-4*00(70) IGHJ3*00(500) IGHG2C*00(62) 0|299|321|0|299|SC0ASA1CST4GST5G|2874.0 20|34|51|301|315||70.0 18|68|68|317|367||500.0 nan ACGGGGACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTTTGGTATGGGT 45 GTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTGGTGGGATGATGATAAG 45 TACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 TGTLKESGPGILQPSQTLSLTCSFS GFSLSTFGMG VGWIRQPSGKGLEWLAH IWWDDDK YYNPALKSRLTISKDTSKNQVFLKIANVDTADTATYY CARMDYDYDRAWFAYW GQGTLVTVSA_ ::::0:75:105:156:177:288:-2:299:301:-3:0:315:317:2:336:367::
330 6 2.26682e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCTACGGTAGTCCAGGGTATGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2856.5) IGHD1-1*00(45) IGHJ2*00(400) nan 0|290|314|0|290||2900.0 31|40|69|290|299||45.0 28|68|68|309|349||400.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCTACGGTAGTCCAGGGTATGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CATVVQGMDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:290:-8:-6:299:309:-8:318:349::
331 6 2.26682e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACGTTACTACCATTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN>NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2922) IGHD2-300(40),IGHD1-100(35),IGHD2-6*00(35) IGHJ2*00(490) IGHD*00(80) 0|294|314|0|294||2940.0 26|34|51|295|303||40.0;5|12|69|297|304||35.0;3|10|51|295|302||35.0 19|68|68|306|355||490.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 29 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACGTTACTACCATTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARRYYHYYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:295:-9:0:303:306:1:324:355::
332 6 2.26682e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGAGGGGGCAGCTCAGGCTACCGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2911) IGHD3-2*00(65) IGHJ2*00(400) nan 0|294|314|0|294||2940.0 19|32|48|301|314||65.0 28|68|68|315|355||400.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGAGGGGGCAGCTCAGGCTACCGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CAREGAAQATDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:301:-3:0:314:315:-8:324:355::
333 6 2.26682e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACTGGCTACACATTCACTGGCTACTGGATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAGATTTTACCTGGAAGTGGTAGTACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTACTGTGCAAGATGGGGCGGGGGAATTTGGGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-9*00(2935.5) IGHD1-1*00(25) IGHJ2*00(400) IGHD*00(80) 0|295|314|0|295||2950.0 21|26|69|305|310||25.0 28|68|68|312|352||400.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGATGAAGCCTGGGGCCTCAGTGAAGCTTTCCTGCAAGGCTACT 45 GGCTACACATTCACTGGCTACTGG 45 ATAGAGTGGGTAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAG 45 ATTTTACCTGGAAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGGGCAAGGCCACATTCACTGCAGATACATCCTCCAACACAGCCTACATGCAACTCAGCAGCCTGACAACTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGATGGGGCGGGGGAATTTGGGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELMKPGASVKLSCKAT GYTFTGYW IEWVKQRPGHGLEWIGE ILPGSGST NYNEKFKGKATFTADTSSNTAYMQLSSLTTEDSAIYY CARWGGGIWDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:305:2:-20:310:312:-8:321:352::
334 6 2.26682e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAGGAGACTACTAGTCTTTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2923) IGHD6-200(35),IGHD2-300(33),IGHD2-8*00(33) IGHJ4*00(530) IGHG2C*00(69) 0|301|321|0|301|SA297G|2981.0 35|42|87|305|312||35.0;29|39|51|301|310|DG34|33.0;29|39|51|301|310|DG34|33.0 21|74|74|312|365||530.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAGGAGACTACTAGTCTTTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARGDY*S_YYAMDYW GQGTSVTVSS_ ::::0:75:105:156:177:288:0:301:305:-6:-16:312:312:-1:334:365::
335 6 2.26682e-05 1 3.33422e-05 CAGGTCCAGCTACAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACACCTTCACTGACTACTATATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGGATTTTTCCTGGAAGTGGTAGTACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTTACTGTAGACAAATCCTCCAGCACAGCCTACATGTTGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTCTGTGCAACTACGGTAGTAGCTACGAGGGACTACTTCTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-75*00(2866.8) IGHD1-1*00(85) IGHJ1*00(501) IGHA*00(310) 0|292|314|0|292||2920.0 30|47|69|292|309||85.0 20|73|73|317|370|SA22T|501.0 nan CAGGTCCAGCTACAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACACCTTCACTGACTACTAT 45 ATAAACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGG 45 ATTTTTCCTGGAAGTGGTAGTACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTTACTGTAGACAAATCCTCCAGCACAGCCTACATGTTGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAACTACGGTAGTAGCTACGAGGGACTACTTCTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYTFTDYY INWVKQRPGQGLEWIGW IFPGSGST YYNEKFKGKATLTVDKSSSTAYMLLSSLTSEDSAVYF CATTVVATRDYFWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:-2:292:292:-7:1:309:317:0:339:370::
336 6 2.26682e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATAACCTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGATATTTATCCTGGTAGTGGTAGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGATCCTCACTACTAGGAGGCCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-55*00(2937.3) IGHD2-400(31),IGHD1-100(30),IGHD2-8*00(30) IGHJ1*00(511) IGHM*00(85) 0|296|314|0|296||2960.0 18|27|51|300|309|ST24G|31.0;4|10|69|300|306||30.0;18|24|51|300|306||30.0 19|73|73|310|364|ST21C|511.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGATGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATAACCTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAGAT 45 ATTTATCCTGGTAGTGGTAGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGATCCTCACTACTAGGAGGCCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQPGAELVKPGASVKMSCKAS GYTFTSYW ITWVKQRPGQGLEWIGD IYPGSGST NYNEKFKSKATLTVDTSSSTAYMQLSSLTSEDSAVYY CARSSLLGGHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:2:296:300:-1:-7:309:310:1:333:364::
349 6 2.26682e-05 1 3.33422e-05 GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTCACTGACTACAACATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTAATTAATCCTAACTATGGTACTACTAGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAAAGGGGGGACCCTGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNINNNN IGHV1-39*00(2914.2) IGHD4-1*00(25) IGHJ3*00(346.2) IGHG2B00(55),IGHG2C00(55) 0|292|314|0|292||2920.0 17|22|33|297|302||25.0 24|68|68|305|349||440.0 ; GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTCACTGACTACAAC 45 ATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTA 45 ATTAATCCTAACTATGGTACTACT 45 AGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAAAGGGGGGACCCTGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 40 EFQLQQSGPELVKPGASVKISCKAS GYSFTDYN MNWVKQSNGKSLEWIGV INPNYGTT SYNQKFKGKATLTVDQSSSTAYMQLNSLTSEDSAVYY CAKGGTLFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:-2:292:297:-6:0:302:305:-4:318:349::
350 6 2.26682e-05 1 3.33422e-05 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACTCTGCAGTCTATTACTGTGCAAGATCGAGATACTACGGTAGCCATGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(1097) IGHD1-100(55),IGHD5-700(51),IGHD6-2*00(51) IGHJ2*00(410) IGHG2B*00(69) 0|219|314|0|219||2190.0 28|39|69|249|260||55.0;36|49|87|214|227|SC39A|51.0;36|49|87|214|227|ST39A|51.0 27|68|68|263|304||410.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 nan nan nan nan GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT nan nan GQGTTLTVSS_ ::::0:75:99:150:174::::249:-5:-7:260:263:-7:273:304::
351 6 2.26682e-05 1 3.33422e-05 ACGGGTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTTTGGTATGGGTGTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACACATTTGGTGGGATGATGATAAGTACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-8*00(2864.3) IGHD2-4*00(70) IGHJ3*00(500) IGHG2C*00(72.5) 0|299|321|0|299|SC0ASA1CST4G|2903.0 20|34|51|301|315||70.0 18|68|68|317|367||500.0 nan ACGGGTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTTTGGTATGGGT 45 GTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTGGTGGGATGATGATAAG 45 TACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAATGGACTATGATTACGACAGGGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 TGTLKESGPGILQPSQTLSLTCSFS GFSLSTFGMG VGWIRQPSGKGLEWLAH IWWDDDK YYNPALKSRLTISKDTSKNQVFLKIANVDTADTATYY CARMDYDYDRAWFAYW GQGTLVTVSA_ ::::0:75:105:156:177:288:-2:299:301:-3:0:315:317:2:336:367::
353 5 1.88902e-05 1 3.33422e-05 TACGGGCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTTAACATTAAAGACGACTATATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGGATTGATCCTGAGAATGGTGATACTGAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTACTACCTTAATTTATTACTACGGTAGTAGCCATGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-4*00(2814) IGHD1-1*00(110) IGHJ2*00(410) IGHG2B00(55),IGHG2C00(55) 0|293|314|0|293|SG0TSG2CST4GST5G|2814.0 21|43|69|296|318||110.0 27|68|68|320|361||410.0 ; TACGGGCAGCTGCAGCAGTCTGGGGCTGAGCTTGTGAGGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTTAACATTAAAGACGACTAT 45 ATGCACTGGGTGAAGCAGAGGCCTGAACAGGGCCTGGAGTGGATTGGATGG 45 ATTGATCCTGAGAATGGTGATACT 45 GAATATGCCTCGAAGTTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTACTACCTTAATTTATTACTACGGTAGTAGCCATGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 YGQLQQSGAELVRPGASVKLSCTAS GFNIKDDY MHWVKQRPEQGLEWIGW IDPENGDT EYASKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CTTLIYYYGSSHDYW GQGTTLTVSS_ ::::0:75:99:150:174:285👎293:296:2:-3:318:320:-7:330:361::
356 5 1.88902e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAATGCTCTACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2920) nan IGHJ2*00(390) IGHD*00(80) 0|292|314|0|292||2920.0 nan 29|68|68|298|337||390.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAATGCTCTACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CAMLYYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-2:292:::::298:-9:306:337::
357 5 1.88902e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACCGATCTACTATGATTACGACGTGGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNBENBBBHDNNNBNNBBNNBNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2853) IGHD2-400(105),IGHD2-700(91) IGHJ2*00(427.8) IGHA*00(77.5) 0|294|314|0|294||2940.0 15|36|51|296|317||105.0;15|36|51|296|317|SG26A|91.0 26|68|68|319|361||420.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACCGATCTACTATGATTACGACGTGGTTGACTACTGG 33 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARPIYYDYDVVDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:296:2:2:317:319:-6:330:361::
358 5 1.88902e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGCCATCTACTATGGTAACCATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2932.8) IGHD2-8*00(75) IGHJ4*00(540) nan 0|294|314|0|294||2940.0 16|31|51|297|312||75.0 20|74|74|313|367||540.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGCCATCTACTATGGTAACCATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARAIYYGNHYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:297:1:-3:312:313:0:336:367::
359 5 1.88902e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGCCATCTACTATGGTAACCATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2932.8) IGHD2-8*00(75) IGHJ4*00(540) IGHD*00(80) 0|294|314|0|294||2940.0 16|31|51|297|312||75.0 20|74|74|313|367||540.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGCCATCTACTATGGTAACCATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARAIYYGNHYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:297:1:-3:312:313:0:336:367::
360 5 1.88902e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACGTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGAGGAGGCTACGAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNLNNNN:7NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2642) IGHD3-200(40),IGHD3-100(35),IGHD5-7*00(35) IGHJ2*00(480) IGHA*00(308.8) 0|294|314|0|285|SC83GDA240DT241DG242DG243DA244DG245DC246DT247DC248|2671.0 25|33|48|289|297||40.0;28|35|51|290|297||35.0;15|22|87|288|295||35.0 20|68|68|298|346||480.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACGTTCACAAGCTATGGT 22 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGAGGAGGCTACGAACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYRSLTSEDSAVYF CAREEATNYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:276:0:285:289:-9:1:297:298:0:315:346::
361 5 1.88902e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2965.5) IGHD4-1*00(35) IGHJ2*00(501) IGHA*00(310) 0|298|321|0|298||2980.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
362 5 1.88902e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2970.3) IGHD4-1*00(35) IGHJ2*00(501) IGHG2C*00(90) 0|298|321|0|298||2980.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 45 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
363 5 1.88902e-05 1 3.33422e-05 CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTCTGGTATGGGTGTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACACATTTACTGGGATGATGACAAGCGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV8-12*00(2951) IGHD4-1*00(35) IGHJ2*00(501) IGHM*00(71) 0|298|321|0|298||2980.0 15|22|33|298|305||35.0 15|68|68|305|358|SA17C|501.0 nan CAGGTTACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGTCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTCTGGTATGGGT 37 GTGAGCTGGATTCGTCAGCCTTCAGGAAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTACTGGGATGATGACAAG 45 CGCTATAACCCATCCCTGAAGAGCCGGCTCACAATCTCCAAGGATACCTCCAGAAACCAGGTATTCCTCAAGATCACCAGTGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAACTGGGACGTCGTACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVTLKESGPGILQSSQTLSLTCSFS GFSLSTSGMG VSWIRQPSGKGLEWLAH IYWDDDK RYNPSLKSRLTISKDTSRNQVFLKITSVDTADTATYY CARTGTSYYFDYW GQGTTLTVSS_ ::::0:75:105:156:177:288:-3:298:298:-4:0:305:305:5:327:358::
364 5 1.88902e-05 1 3.33422e-05 CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGCTACAGCTTCACAAGCTACTATATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGGATTTATCCTGGAAGTGGTAATACTAAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTACTGTGCAAGAGGGCTCTATGGTAACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-66*00(2920.7) IGHD2-800(40),IGHD2-700(35) IGHJ2*00(480) nan 0|294|314|0|294||2940.0 21|29|51|299|307||40.0;21|28|51|299|306||35.0 20|68|68|307|355||480.0 nan CAGGTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGCTACAGCTTCACAAGCTACTAT 45 ATACACTGGGTGAAGCAGAGGCCTGGACAGGGACTTGAGTGGATTGGATGG 32 ATTTATCCTGGAAGTGGTAATACT 45 AAGTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACGGCAGACACATCCTCCAGCACTGCCTACATGCAGCTCAGCAGCCTAACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCAAGAGGGCTCTATGGTAACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGPELVKPGASVKISCKAS GYSFTSYY IHWVKQRPGQGLEWIGW IYPGSGNT KYNEKFKGKATLTADTSSSTAYMQLSSLTSEDSAVYY CARGLYGNYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:299:-4:-5:307:307:0:324:355::
365 5 1.88902e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTAAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGTGATTGATCCTTCTGATAGTTATACTAACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCCCCTATTACTACGGCGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-59*00(2854) IGHD1-1*00(55) IGHJ2*00(458.2) IGHG2B00(55),IGHG2C00(55) 0|290|314|0|290||2900.0 25|36|69|293|304||55.0 22|68|68|306|352||460.0 ; CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGACTTCAGTGAAGTTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTAAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATCGGAGTG 45 ATTGATCCTTCTGATAGTTATACT 45 AACTACAATCAAAAGTTCAAGGGCAAGGCCACATTGACTGTAGACACATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 45 TGTGCCCCTATTACTACGGCGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAELVRPGTSVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGV IDPSDSYT NYNQKFKGKATLTVDTSSSTAYMQLSSLTSEDSAVYY CAPITTAYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-4:290:293:-2:-10:304:306:-2:321:352::
366 5 1.88902e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGGACAAGGCCTTGAGTGGATTGGAAATATTAATCCTAGCAATGGTGGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGATTTTATTACTACGGTAGTAGCCTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-53*00(1661) IGHD1-1*00(85) IGHJ2*00(420) IGHA*00(305.3) 0|298|314|0|239|DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123SC295T|1661.0 26|43|69|239|256||85.0 26|68|68|257|299||420.0 nan CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTG 45 nan 0 GACAAGGCCTTGAGTGGATTGGAAAT 45 ATTAATCCTAGCAATGGTGGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGATTTTATTACTACGGTAGTAGCCTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGTEL_EAWGFSEAVL nan DKAL_WIGN INPSNGGT NYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYY CARFYYYGSSLDYW GQGTTLTVSS_ ::::0:65:65:91:115:226:4:239:239:-3:-3:256:257:-6:268:299::
385 5 1.88902e-05 1 3.33422e-05 GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGAGGATGGTGAAACTAAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGAGCCCTCTATGATGGTTACTACTTGGGTTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-2*00(2911) IGHD2-3*00(85) IGHJ3*00(460) IGHM*00(85) 0|294|314|0|294||2940.0 17|34|51|298|315||85.0 22|68|68|321|367||460.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 45 GGCTTCAACATTAAAGACTACTAT 45 ATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGAGGATGGTGAAACT 45 AAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTGCTAGAGCCCTCTATGATGGTTACTACTTGGGTTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 EVQLQQSGAELVKPGASVKLSCTAS GFNIKDYY MHWVKQRTEQGLEWIGR IDPEDGET KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CARALYDGYYLGWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:298:0:0:315:321:-2:336:367::
386 5 1.88902e-05 1 3.33422e-05 GAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGATTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTTACTGGCTACTTTATGAACTGGGTGATGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGACGTATTAATCCTTACAATGGTGATACTTTCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAATCCTCTAGCACAGCCCACATGGAGCTCCGGAGCCTGACATCTGAGGACTCTGCAGTCTATTATTGTGCAAGAAATGGGTATCCTTATTACTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN?NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-20*00(2905.2) IGHD5-200(25),IGHD5-300(25),IGHD5-4*00(25) IGHJ4*00(550) IGHD*00(77.2) 0|294|314|0|294||2940.0 3|8|30|298|303||25.0;3|8|30|298|303||25.0;3|8|30|298|303||25.0 19|74|74|306|361||550.0 nan GAGGTTCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGGGATTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTTACTGGCTACTTT 45 ATGAACTGGGTGATGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGACGT 30 ATTAATCCTTACAATGGTGATACT 45 TTCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAATCCTCTAGCACAGCCCACATGGAGCTCCGGAGCCTGACATCTGAGGACTCTGCAGTCTATTAT 45 TGTGCAAGAAATGGGTATCCTTATTACTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 EVQLQQSGPELVKPGDSVKISCKAS GYSFTGYF MNWVMQSHGKSLEWIGR INPYNGDT FYNQKFKGKATLTVDKSSSTAHMELRSLTSEDSAVYY CARNGYPYYYAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:298:7:-12:303:306:1:330:361::
387 5 1.88902e-05 1 3.33422e-05 GAAGTGAAGCTGGTGGAGTCTGAGGGAGGCTTAGTGCAGCCTGGAAGTTCCATGAAACTCTCCTGCACAGCCTCTGGATTCACTTTCAGTGACTATTACATGGCTTGGGTCCGCCAGGTTCCAGAAAAGGGTCTAGAATGGGTTGCAAACATTAATTATGATGGTAGTAGCACCTACTATCTGGACTCCTTGAAGAGCCGTTTCATCATCTCGAGAGACAATGCAAAGAACATTCTATACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCACGTATTACTGTGCAAGAAGGGTGGTCCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV5-16*00(2925.5) nan IGHJ1*00(502.8) nan 0|294|314|0|294||2940.0 nan 22|73|73|304|355||510.0 nan GAAGTGAAGCTGGTGGAGTCTGAGGGAGGCTTAGTGCAGCCTGGAAGTTCCATGAAACTCTCCTGCACAGCCTCT 45 GGATTCACTTTCAGTGACTATTAC 45 ATGGCTTGGGTCCGCCAGGTTCCAGAAAAGGGTCTAGAATGGGTTGCAAAC 45 ATTAATTATGATGGTAGTAGCACC 45 TACTATCTGGACTCCTTGAAGAGCCGTTTCATCATCTCGAGAGACAATGCAAAGAACATTCTATACCTGCAAATGAGCAGTCTGAAGTCTGAGGACACAGCCACGTATTAC 45 TGTGCAAGAAGGGTGGTCCACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVKLVESEGGLVQPGSSMKLSCTAS GFTFSDYY MAWVRQVPEKGLEWVAN INYDGSST YYLDSLKSRFIISRDNAKNILYLQMSSLKSEDTATYY CARRVVHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:::::304:-2:324:355::
393 4 1.51121e-05 1 3.33422e-05 TACGGGACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCTGGGTTTTCACTGAGCACTTTTGGTATGGGTGTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACACATTTGGTGGGATGATGATAAGTACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTACTGTGCTCGAATAGAGGGTAATGGCGGTTACTATTCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN:NNNNNNNNNNNN IGHV8-8*00(2884.3) IGHD1-100(25),IGHD2-400(25),IGHD2-8*00(25) IGHJ4*00(491.3) IGHG2B00(55),IGHG2C00(55) 0|301|321|0|301|SC0TSG2CST4GST5G|2894.0 15|20|69|304|309||25.0;3|8|51|304|309||25.0;25|30|51|303|308||25.0 21|74|74|314|367|SG28T|501.0 ; TACGGGACTCTGAAAGAGTCTGGCCCTGGGATATTGCAGCCCTCCCAGACCCTCAGTCTGACTTGTTCTTTCTCT 45 GGGTTTTCACTGAGCACTTTTGGTATGGGT 45 GTAGGCTGGATTCGTCAGCCTTCAGGGAAGGGTCTGGAGTGGCTGGCACAC 45 ATTTGGTGGGATGATGATAAG 45 TACTATAACCCAGCCCTGAAGAGTCGGCTCACAATCTCCAAGGATACCTCCAAAAACCAGGTATTCCTCAAGATCGCCAATGTGGACACTGCAGATACTGCCACATACTAC 45 TGTGCTCGAATAGAGGGTAATGGCGGTTACTATTCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 25 YGTLKESGPGILQPSQTLSLTCSFS GFSLSTFGMG VGWIRQPSGKGLEWLAH IWWDDDK YYNPALKSRLTISKDTSKNQVFLKIANVDTADTATYY CARIEGNGGYYSMDYW GQGTSVTVSS_ ::::0:75:105:156:177:288:0:301:304:8:-26:309:314:-1:336:367::
395 4 1.51121e-05 1 3.33422e-05 CGGGAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGACCGATCTACTATGATTACGACGTGGTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2797) IGHD2-400(105),IGHD2-700(91) IGHJ2*00(420) IGHG2B00(55),IGHG2C00(55) 0|294|314|0|291|SA1GDT4DT5DC6|2797.0 15|36|51|293|314||105.0;15|36|51|293|314|SG26A|91.0 26|68|68|316|358||420.0 ; CGGGAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGACCGATCTACTATGATTACGACGTGGTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 RELQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARPIYYDYDVVDYW GQGTTLTVSS_ ::::0:72:96:147:171:282:0:291:293:2:2:314:316:-6:327:358::
396 4 1.51121e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGGGCTGAATTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAAGCTTCTGGCTACGCATTCAGTAGCTACTGGATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACAGATTTATCCTGGAGATGGTGATACTAACTACAACGGAAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTCTGTGCAGGGGCCTTTGGTCCCCTTTACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-80*00(2852) IGHD2-500(25),IGHD2-600(25),IGHD4-1*00(25) IGHJ2*00(391) IGHG2B00(55),IGHG2C00(55) 0|291|314|0|291|SG29ASC30T|2852.0 15|20|51|293|298||25.0;15|20|51|293|298||25.0;0|5|33|301|306||25.0 26|68|68|307|349|SG28T|391.0 ; CAGGTTCAGCTGCAGCAGTCTGGGGCTGAATTGGTGAAGCCTGGGGCCTCAGTGAAGATTTCCTGCAAAGCTTCT 45 GGCTACGCATTCAGTAGCTACTGG 45 ATGAACTGGGTGAAGCAGAGGCCTGGAAAGGGTCTTGAGTGGATTGGACAG 45 ATTTATCCTGGAGATGGTGATACT 45 AACTACAACGGAAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACCTCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAGGGGCCTTTGGTCCCCTTTACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELVKPGASVKISCKAS GYAFSSYW MNWVKQRPGKGLEWIGQ IYPGDGDT NYNGKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYF CAGAFGPLYYW GQGTTLTVSS_ ::::0:75:99:150:174:285:-3:291:293:2:-14:298:307:-6:318:349::
397 4 1.51121e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAGGGGTTACGACGGGCGCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2920.7) IGHD2-7*00(50) IGHJ3*00(490) IGHD*00(80) 0|294|314|0|294||2940.0 25|35|51|296|306||50.0 19|68|68|309|358||490.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 44 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAGGGGTTACGACGGGCGCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARGVTTGAWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:296:-8:1:306:309:1:327:358::
398 4 1.51121e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGAAGTAACGTCCTGGGACACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2940) IGHD4-100(35),IGHD2-300(30),IGHD2-6*00(30) IGHJ1*00(510) IGHD*00(81.7) 0|294|314|0|294||2940.0 15|22|33|303|310||35.0;2|8|51|294|300||30.0;25|31|51|294|300||30.0 22|73|73|310|361||510.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGAAGTAACGTCCTGGGACACTGGTACTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARSNVLGHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:303:-4:0:310:310:-2:330:361::
399 4 1.51121e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAATCATTACTACGGAGGTTCCTGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2920) IGHD1-1*00(50) IGHJ3*00(480) IGHD*00(78.8) 0|292|314|0|292||2920.0 26|36|69|295|305||50.0 20|68|68|310|358||480.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAATCATTACTACGGAGGTTCCTGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CANHYYGGSWFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:-2:292:295:-3:-10:305:310:0:327:358::
400 4 1.51121e-05 1 3.33422e-05 CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTAAGGCCTGGGACTTCAGTGAAGATGTCCTGCAAGGCTTCTGGATACACCTTCACTAACTACTGGATAGGTTGGGCAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGATATTTACCCTGGAGGTGGTTATACTAACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGTTCAGCAGCCTGACATCTGAGGACTCTGCCATCTATTACTGTGCAAGAAGGGGGTTCTACCCGACGGGTTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-63*00(2930.3) IGHD2-300(28),IGHD1-100(25),IGHD2-8*00(25) IGHJ2*00(430) IGHD*00(80) 0|294|314|0|294||2940.0 25|34|51|298|306|DA29|28.0;7|12|69|302|307||25.0;17|22|51|301|306||25.0 25|68|68|315|358||430.0 nan CAGGTCCAGCTGCAGCAGTCTGGAGCTGAGCTGGTAAGGCCTGGGACTTCAGTGAAGATGTCCTGCAAGGCTTCT 34 GGATACACCTTCACTAACTACTGG 45 ATAGGTTGGGCAAAGCAGAGGCCTGGACATGGCCTTGAGTGGATTGGAGAT 42 ATTTACCCTGGAGGTGGTTATACT 45 AACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCCTACATGCAGTTCAGCAGCCTGACATCTGAGGACTCTGCCATCTATTAC 45 TGTGCAAGAAGGGGGTTCTACCCGACGGGTTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELVRPGTSVKMSCKAS GYTFTNYW IGWAKQRPGHGLEWIGD IYPGGGYT NYNEKFKGKATLTADKSSSTAYMQFSSLTSEDSAIYY CARRGFYPTGFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:298:-8:0:306:315:-5:327:358::
401 4 1.51121e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTGGACAAGGCCTTGAATGGATTGGTAACATTTACCCTTCTGATAGTGAAACTCACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTACTGTGCAACTGGGACGTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-61*00(1485) IGHD4-1*00(40) IGHJ2*00(460) IGHM*00(85) 0|292|314|0|233|DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DG102DA103DT104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123|1630.0 15|23|33|233|241||40.0 22|68|68|241|287||460.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTGGTGAGGCCTGGGTCTTCAGTGAAGCTGTCCTG 45 nan 0 GACAAGGCCTTGAATGGATTGGTAAC 45 ATTTACCCTTCTGATAGTGAAACT 45 CACTACAATCAAAAGTTCAAGGACAAGGCCACATTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAC 43 TGTGCAACTGGGACGTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGAEL_EAWVFSEAVL nan DKAL_WIGN IYPSDSET HYNQKFKDKATLTVDKSSSTAYMQLSSLTSEDSAVYY CATGTYFDYW GQGTTLTVSS_ ::::0:65:65:91:115:226:-2:233:233:-4:1:241:241:-2:256:287::
402 4 1.51121e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAAATATTAATCCTAGCAATGGTGGTACTAACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAGTGCGTAACGGGTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-53*00(2932.8) IGHD2-7*00(30) IGHJ2*00(430) nan 0|294|314|0|294||2940.0 2|8|51|297|303||30.0 25|68|68|306|349||430.0 nan CAGGTCCAACTGCAGCAGCCTGGGACTGAACTGGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACAAGGCCTTGAGTGGATTGGAAAT 45 ATTAATCCTAGCAATGGTGGTACT 45 AACTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAATCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAGTGCGTAACGGGTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQPGTELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGQGLEWIGN INPSNGGT NYNEKFKSKATLTVDKSSSTAYMQLSSLTSEDSAVYY CARVRNGFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:297:15:-26:303:306:-5:318:349::
426 4 1.51121e-05 1 3.33422e-05 GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCTGGTTACTCATTCACTGACTACAACATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTAATTAATCCTAACTATGGTACTACTAGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGACGGGCCTACTATAGGGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-39*00(2940) IGHD2-500(60),IGHD2-600(60) IGHJ4*00(460) IGHG2B*00(78.3) 0|294|314|0|294||2940.0 15|27|51|296|308||60.0;15|27|51|296|308||60.0 28|74|74|309|355||460.0 nan GAGTTCCAGCTGCAGCAGTCTGGACCTGAGCTGGTGAAGCCTGGCGCTTCAGTGAAGATATCCTGCAAGGCTTCT 45 GGTTACTCATTCACTGACTACAAC 45 ATGAACTGGGTGAAGCAGAGCAATGGAAAGAGCCTTGAGTGGATTGGAGTA 45 ATTAATCCTAACTATGGTACTACT 45 AGCTACAATCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACCAATCTTCCAGCACAGCCTACATGCAGCTCAACAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGACGGGCCTACTATAGGGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 EFQLQQSGPELVKPGASVKISCKAS GYSFTDYN MNWVKQSNGKSLEWIGV INPNYGTT SYNQKFKGKATLTVDQSSSTAYMQLNSLTSEDSAVYY CARRAYYRAMDYW GQGTSVTVSS_ ::::0:75:99:150:174:285:0:294:296:2:-7:308:309:-8:324:355::
427 4 1.51121e-05 1 3.33422e-05 GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCTGGCTTCAACATTAAAGACTACTATATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGGATTGATCCTGAGGATGGTGAAACTAAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTACTGTGCTAGGGACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNJNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV14-2*00(2901) nan IGHJ2*00(480) IGHA*00(310) 0|293|314|0|293||2930.0 nan 20|68|68|295|343||480.0 nan GAGGTTCAGCTGCAGCAGTCTGGGGCAGAGCTTGTGAAGCCAGGGGCCTCAGTCAAGTTGTCCTGCACAGCTTCT 41 GGCTTCAACATTAAAGACTACTAT 45 ATGCACTGGGTGAAGCAGAGGACTGAACAGGGCCTGGAGTGGATTGGAAGG 45 ATTGATCCTGAGGATGGTGAAACT 45 AAATATGCCCCGAAATTCCAGGGCAAGGCCACTATAACAGCAGACACATCCTCCAACACAGCCTACCTGCAGCTCAGCAGCCTGACATCTGAGGACACTGCCGTCTATTAC 45 TGTGCTAGGGACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 EVQLQQSGAELVKPGASVKLSCTAS GFNIKDYY MHWVKQRTEQGLEWIGR IDPEDGET KYAPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYY CARDYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285👎293:::::295:0:312:343::
428 4 1.51121e-05 1 3.33422e-05 GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCTGGATACACGTTCACTGACTACTACATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGATATTAATCCTAACAATGGTGGTACTAGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTACTGTGCAAGAGTGAGGAAAAATTACTACGGTAGTAGGGGGTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-26*00(2940) IGHD1-1*00(80) IGHJ1*00(430) nan 0|294|314|0|294||2940.0 26|42|69|304|320||80.0 30|73|73|324|367||430.0 nan GAGGTCCAGCTGCAACAATCTGGACCTGAGCTGGTGAAGCCTGGGGCTTCAGTGAAGATATCCTGTAAGGCTTCT 45 GGATACACGTTCACTGACTACTAC 45 ATGAACTGGGTGAAGCAGAGCCATGGAAAGAGCCTTGAGTGGATTGGAGAT 45 ATTAATCCTAACAATGGTGGTACT 45 AGCTACAACCAGAAGTTCAAGGGCAAGGCCACATTGACTGTAGACAAGTCCTCCAGCACAGCCTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCAGTCTATTAC 45 TGTGCAAGAGTGAGGAAAAATTACTACGGTAGTAGGGGGTTCGATGTCTGG 45 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 EVQLQQSGPELVKPGASVKISCKAS GYTFTDYY MNWVKQSHGKSLEWIGD INPNNGGT SYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYY CARVRKNYYGSRGFDVW GTGTTVTVSS_ ::::0:75:99:150:174:285:0:294:304:-3:-4:320:324:-10:336:367::
430 4 1.51121e-05 1 3.33422e-05 ACGGGGAAGCTGGTGGAGTCTGGAGGAGGCTTGGTACAGCCTGGGGGTTCTCTGAGTCTCTCCTGTGCAGCTTCTGGATTCACCTTCACTGATTACTACATGAGCTGGGTCCGCCAGCCTCCAGGGAAGGCACTTGAGTGGTTGGGTTTTATTAGAAACAAAGCTAATGGTTACACAACAGAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAATGCCCTGAGAGCTGAGGACAGTGCCACTTATTACTGTGCAAGATCCCCCTATAGTAACTACCTCCACTGGTACTTCGATGTCTGGGGCACAGGGACCACGGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV7-3*00(2923) IGHD2-500(65),IGHD2-600(65) IGHJ1*00(510) IGHG2B00(55),IGHG2C00(55) 0|301|324|0|301|SG0ASA1CST4G|2923.0 21|34|51|305|318||65.0;21|34|51|305|318||65.0 22|73|73|322|373||510.0 ; ACGGGGAAGCTGGTGGAGTCTGGAGGAGGCTTGGTACAGCCTGGGGGTTCTCTGAGTCTCTCCTGTGCAGCTTCT 45 GGATTCACCTTCACTGATTACTAC 45 ATGAGCTGGGTCCGCCAGCCTCCAGGGAAGGCACTTGAGTGGTTGGGTTTT 45 ATTAGAAACAAAGCTAATGGTTACACAACA 45 GAGTACAGTGCATCTGTGAAGGGTCGGTTCACCATCTCCAGAGATAATTCCCAAAGCATCCTCTATCTTCAAATGAATGCCCTGAGAGCTGAGGACAGTGCCACTTATTAC 45 TGTGCAAGATCCCCCTATAGTAACTACCTCCACTGGTACTTCGATGTCTGG 43 GGCACAGGGACCACGGTCACCGTCTCCTCAG 45 TGKLVESGGGLVQPGGSLSLSCAAS GFTFTDYY MSWVRQPPGKALEWLGF IRNKANGYTT EYSASVKGRFTISRDNSQSILYLQMNALRAEDSATYY CARSPYSNYLHWYFDVW GTGTTVTVSS_ ::::0:75:99:150:180:291:-3:301:305:-4:0:318:322:-2:342:373::
432 3 1.13341e-05 1 3.33422e-05 CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACAAGCTATGGTATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAGATTTATCCTAGAAGTGGTAATACTTACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTCTGTGCAAGATGGGTCGGTGACTACTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-81*00(2950) nan IGHJ2*00(480) nan 0|295|314|0|295||2950.0 nan 20|68|68|304|352||480.0 nan CAGGTTCAGCTGCAGCAGTCTGGAGCTGAGCTGGCGAGGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACAAGCTATGGT 45 ATAAGCTGGGTGAAGCAGAGAACTGGACAGGGCCTTGAGTGGATTGGAGAG 45 ATTTATCCTAGAAGTGGTAATACT 45 TACTACAATGAGAAGTTCAAGGGCAAGGCCACACTGACTGCAGACAAATCCTCCAGCACAGCGTACATGGAGCTCCGCAGCCTGACATCTGAGGACTCTGCGGTCTATTTC 45 TGTGCAAGATGGGTCGGTGACTACTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QVQLQQSGAELARPGASVKLSCKAS GYTFTSYG ISWVKQRTGQGLEWIGE IYPRSGNT YYNEKFKGKATLTADKSSSTAYMELRSLTSEDSAVYF CARWVGDYFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:1:295:::::304:0:321:352::
433 3 1.13341e-05 1 3.33422e-05 CAGGTCCAATTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGGGGTCAAGGAACCTCAGTCACCGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(1592),IGHV1-62-300(1563) IGHD2-8*00(50) IGHJ4*00(500) IGHG2C*00(78.3) 0|294|314|0|235|SC9TSC30TDC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121DT122DG123|1592.0;0|294|314|0|235|SC9TSC30TDA63DG64DC65DA66DA67DG68DG69DC70DT71DT72DC73DT74DG75DG76DC77DT78DA79DC80DA81DC82DC83DT84DT85DC86DA87DC88DC89DA90DG91DC92DT93DA94DC95DT96DG97DG98DA99DT100DG101DC102DA103DC104DT105DG106DG107DG108DT109DG110DA111DA112DG113DC114DA115DG116DA117DG118DG119DC120DC121SC284T|1563.0 21|31|51|240|250||50.0 24|74|74|252|302||500.0 nan CAGGTCCAATTGCAGCAGCCTGGGGCTGAGTTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTG 45 nan 0 GACGAGGCCTTGAGTGGATTGGAAGG 45 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 45 TGTGCAAGAAGGGGCTATGGTAACCTCTATGCTATGGACTACTGG 45 GGTCAAGGAACCTCAGTCACCGTCTCCTCAG 45 QVQLQQPGAEF_EAWGFSEAVL nan DEAL_WIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARRGYGNLYAMDYW GQGTSVTVSS_ ::::0:65:65:91:115:226:0:235:240:-4:-3:250:252:-4:271:302::
434 3 1.13341e-05 1 3.33422e-05 CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCTGGCTACACCTTCACCAGCTACTGGATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGGATTGATCCTAATAGTGGTGGTACTAAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTATTGTGCAAGAGGGGGACAGGGGTTTGCTTACTGGGGCCAAGGGACTCTGGTCACTGTCTCTGCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNJNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNJNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV1-7200(2891.7),IGHV1-62-300(2833.7) IGHD3-200(25),IGHD4-100(25),IGHD5-8*00(25) IGHJ3*00(450) nan 0|294|314|0|294||2940.0;0|294|314|0|294|SA63TSC284T|2882.0 17|22|48|298|303||25.0;17|22|33|296|301||25.0;30|35|87|298|303||25.0 23|68|68|304|349||450.0 nan CAGGTCCAACTGCAGCAGCCTGGGGCTGAGCTTGTGAAGCCTGGGGCTTCAGTGAAGCTGTCCTGCAAGGCTTCT 45 GGCTACACCTTCACCAGCTACTGG 45 ATGCACTGGGTGAAGCAGAGGCCTGGACGAGGCCTTGAGTGGATTGGAAGG 41 ATTGATCCTAATAGTGGTGGTACT 45 AAGTACAATGAGAAGTTCAAGAGCAAGGCCACACTGACTGTAGACAAACCCTCCAGCACAGCCTACATGCAGCTCAGCAGCCTGACATCTGAGGACTCTGCGGTCTATTAT 41 TGTGCAAGAGGGGGACAGGGGTTTGCTTACTGG 45 GGCCAAGGGACTCTGGTCACTGTCTCTGCAG 45 QVQLQQPGAELVKPGASVKLSCKAS GYTFTSYW MHWVKQRPGRGLEWIGR IDPNSGGT KYNEKFKSKATLTVDKPSSTAYMQLSSLTSEDSAVYY CARGGQGFAYW GQGTLVTVSA_ ::::0:75:99:150:174:285:0:294:298:-1:-10:303:304:-3:318:349::
437 3 1.13341e-05 1 3.33422e-05 CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCTGGGTATACCTTCACAACCTATGGAATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGGATAAACACCTACTCTGGAGTGCCAACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTCTGTGCAAGACGGTATTACTACGGTAGTAGTTTTGACTACTGGGGCCAAGGCACCACTCTCACAGTCTCCTCAG NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNBNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN IGHV9-3*00(2930.3) IGHD1-1*00(85) IGHJ2*00(430) nan 0|294|314|0|294||2940.0 25|42|69|297|314||85.0 25|68|68|315|358||430.0 nan CAGATCCAGTTGGTACAGTCTGGACCTGAGCTGAAGAAGCCTGGAGAGACAGTCAAGATCTCCTGCAAGGCTTCT 33 GGGTATACCTTCACAACCTATGGA 45 ATGAGCTGGGTGAAACAGGCTCCAGGAAAGGGTTTAAAGTGGATGGGCTGG 32 ATAAACACCTACTCTGGAGTGCCA 45 ACATATGCTGATGACTTCAAGGGACGGTTTGCCTTCTCTTTGGAAACCTCTGCCAGCACTGCCTATTTGCAGATCAACAACCTCAAAAATGAGGACACGGCTACATATTTC 45 TGTGCAAGACGGTATTACTACGGTAGTAGTTTTGACTACTGG 45 GGCCAAGGCACCACTCTCACAGTCTCCTCAG 45 QIQLVQSGPELKKPGETVKISCKAS GYTFTTYG MSWVKQAPGKGLKWMGW INTYSGVP TYADDFKGRFAFSLETSASTAYLQINNLKNEDTATYF CARRYYYGSSFDYW GQGTTLTVSS_ ::::0:75:99:150:174:285:0:294:297:-2:-4:314:315:-5:327:358::

In order to run the analysis for all samples in the project on Linux we can use GNU Parallel in the following way:

#!/usr/bin/env bash

mkdir -p results/

ls raw/*R1* | \
    parallel -j 4 \
    'mixcr analyze neb-mouse-rna-xcr-umi-nebnext \
    {} \
    {=s:R1:R2:=} \
    {=s:.*/:results/:;s:_R.*::=}'

Under the hood of mixcr analyze pipeline

Under the hood, mixcr analyze nebnext-mouse-bcr-full-length command that we use above actually executes the following pipeline of MiXCR actions:

align

Performs:

  • alignment of raw sequencing reads against reference database of V-, D-, J- and C- gene segments
  • pattern matching of tag pattern sequence and extraction of barcodes
mixcr align \
    -p generic-amplicon-with-umi
    --species mmu \
    --report result/Multi_TRA_10ng_3.align.report.txt \
    --json-report result/Multi_TRA_10ng_3.align.report.json \
    --tagPattern "^N{22}(R1:*) \ ^(UMI:N{17})(R2:*)" \
    -OvParameters.parameters.floatingLeftBound=false \
    -OjParameters.parameters.floatingRightBound=false \
    -OcParameters.parameters.floatingRightBound=false \
    raw/mouse_3_Cd4Cre_R1.fastq.gz \
    raw/mouse_3_Cd4Cre_R2.fastq.gz \
    results/mouse_3_Cd4Cre.vdjca

Options --report and --json-report are specified here explicitly. Since we start from RNA data we use VTranscriptWithout5UTRWithP for the alignment of V segments (see Gene features and anchor points.

--tagPattern "^N{22}(R1:*) \ ^(UMI:N{17})(R2:*)"
this pattern sets the UMI location and also trims C-gene primer sequences.
-OvParameters.parameters.floatingLeftBound=false -OjParameters.parameters floatingRightBound=false -OcParameters.parameters.floatingRightBound=false
These options determine global vs local alignment algorithm on the bounds of gene segments. We want to use global alignment on all gene-segments bounds because no V-gene primers were used and C-gene primers were trimmed using --tagPattern.

This step utilizes all available CPUs and scales perfectly. When there are a lot of CPUs, the only limiting factor is the speed of disk I/O. To limit the number of used CPUs one can pass --threads N option.

refineTagsAndSort

Corrects sequencing and PCR errors inside barcode sequences. This step does extremely important job by correcting artificial diversity caused by errors in barcodes. In the considered example project it corrects only sequences of UMIs.

mixcr refineTagsAndSort \
   --report results/mouse_3_Cd4Cre.refine.report.txt \
   --json-report results/mouse_3_Cd4Cre.refine.report.json \
   results/mouse_3_Cd4Cre.vdjca \
   results/mouse_3_Cd4Cre.refined.vdjca

assemble

Assembles clonotypes and applies several layers of errors correction:

  • assembly consensus CDR3 sequence
  • quality-awared correction for sequencing errors
  • clustering to correct for PCR errors
mixcr assemble \
    --report results/mouse_3_Cd4Cre.assemble.report.txt \
    --json-report results/mouse_3_Cd4Cre.assemble.report.json \
    -OassemblingFeatures={FR1Begin:FR4End} \
    -OseparateByC=true \
    mouse_3_Cd4Cre.corrected.vdjca \
    mouse_3_Cd4Cre.clns
-OassemblingFeatures=VDJRegion
By default nebnext-mouse-bcr-full-length preset assembles clones by VDJRegion. There is also an alternative preset nebnext-mouse-bcr-cdr3 which assembles clones only by CDR3 sequence.
-separateByC: true
Separate clones with the same assembling feature, but different C-genes, which is essential for isotype identification.

Options --report and --json-report are specified here explicitly so that the report files will be appended with assembly report.

exportClones

Finally, to export clonotype tables in tabular form exportClones is used. By default mixcr analyze will export all available chains into separate files which is equivalent to running a set of the following commands :

mixcr exportClones \
     results/mouse_3_Cd4Cre.clns \
     results/mouse_3_Cd4Cre.tsv
By default mixcr export will create separate files for every receptor chain. To change this behavior and export all chains in a single file use --dont-split-files option, or export only a desired set of chains using --chains option.

Quality control

Now when the upstream analysis is finished we can move on to quality control. First lets look at the alignment report plot.

mixcr exportQc align results/*.clns figs/alignQc.pdf

alignQc.svg

We see that all samples have a very high score of successfully aligned reads. No significant issues present.

Next, lets examine chain usage distribution:

mixcr exportQc chainUsage results/*.clns figs/chainUsage.pdf

chainUsage.svg

This plot tells us that all samples mostly consist of IGH and IGK with relatively small numbers of IGL, which is pretty much what we would expect. Thus, quality reports look good, and we can move on to downstream analysis.

Downstream analysis

There are two types of basic downstream analysis: individual and overlap. Individual computes CDR3 metrics, diversity and gene usage metrics for each dataset. Overlap computes statistical metrics of repertoires overlap. In both cases MiXCR applies appropriate sample normalization.

To run postanalysis routines we need to prepare a metadata file in a .tsv or .csv format. Metadata must contain a sample column which will be used to match metadata with cloneset files. Bellow you can find a metadata table for our samples.

Metadata
sample genotype
mouse_1_Cd4Cre Bcl6fl/flCd4Cre
mouse_1 Bcl6fl/fl
mouse_2_Cd4Cre Bcl6fl/flCd4Cre
mouse_2 Bcl6fl/fl
mouse_3_Cd4Cre Bcl6fl/flCd4Cre
mouse_3 Bcl6fl/fl
mouse_4_Cd4Cre Bcl6fl/flCd4Cre
mouse_4 Bcl6fl/fl

Individual postanalysis

To compute a set of individual metrics run the following command:

mkdir -p pa/
mixcr postanalysis individual \
    --metadata metadata.tsv \
    --default-downsampling count-umi-auto \
    --default-weight-function umi \
    --only-productive \
    --tables pa/pa.i.tsv \
    --preproc-tables pa/preproc.i.tsv \
    results/*.clns \
    pa/individual.json.gz

The meaning of specified options is the following:

--metadata
specified metadata file to use
--default-downsampling
downsampling applied to normalize the clonesets. Without appropriate normalization it is not possible to make a statistical comparisons between datasets. In the considered case we normalize data to the same number of UMIs, and this number is computed automatically. See reference for all downsampling options. Default downsampling may be overridden for individual metrics.
--default-weight-function
defines weight of each clonotype. Set umi because our data is barcoded and instead of using reads count we can use UMIs count for every clone as a precise measure.
--only-productive
drop clonotypes with out-of-frame CDR3 sequences or containing stop codons
--tables
path for postanalysis metrics in a tabular form
--preproc-tables
path for tabular summary of the applied downsampling and other samples preprocessing (for example filtering productive clonotypes)

After execution, we will have the following files:

> ls pa/

# gzipped JSON with all results 
individual.json.gz

# summary of applied preprocessors
preproc.i.IGH.tsv
preproc.i.IGK.tsv
preproc.i.IGL.tsv

# diversity tables
pa.i.diversity.IGH.tsv
pa.i.diversity.IGK.tsv
pa.i.diversity.IGL.tsv

# CDR3 metrics tables & CDR3 properties
pa.i.cdr3metrics.IGH.tsv
pa.i.cdr3metrics.IGK.tsv
pa.i.cdr3metrics.IGL.tsv


# V- / J- / VJ- usage tables
pa.i.vUsage.IGH.tsv
pa.i.JUsage.IGH.tsv
pa.i.VJUsage.IGK.tsv
pa.i.vUsage.IGH.tsv
pa.i.JUsage.IGK.tsv
pa.i.VJUsage.IGL.tsv
pa.i.vUsage.IGH.tsv
pa.i.JUsage.IGK.tsv
pa.i.VJUsage.IGL.tsv

# Isotype usage table
pa.i.IsotypeUsage.IGH.tsv
pa.i.IsotypeUsage.IGK.tsv
pa.i.IsotypeUsage.IGL.tsv


#V Spectratype tables
pa.i.VSpectratype.IGH.tsv
pa.i.VSpectratypeMean.IGH.tsv
pa.i.VSpectratype.IGK.tsv
pa.i.VSpectratypeMean.IGK.tsv
pa.i.VSpectratype.IGL.tsv
pa.i.VSpectratypeMean.IGL.tsv

Preprocessing summary tables (e.g. preproc.i.IGH.tsv) contain detailed information on how downsampling was applied for each metric:

characteristic sample preprocessor nElementsBefore sumWeightBefore nElementsAfter sumWeightAfter preprocessor#1 nElementsBefore#1 sumWeightBefore#1 nElementsAfter#1 sumWeightAfter#1 preprocessor#2 nElementsBefore#2 sumWeightBefore#2 nElementsAfter#2 sumWeightAfter#2 preprocessor#3 nElementsBefore#3 sumWeightBefore#3 nElementsAfter#3 sumWeightAfter#3 preprocessor#4 nElementsBefore#4 sumWeightBefore#4 nElementsAfter#4 sumWeightAfter#4
VFamilyUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan nan
VFamilyUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan nan
VFamilyUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan nan
VFamilyUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan nan
VFamilyUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan nan
VFamilyUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan nan
VFamilyUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan nan
VFamilyUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan nan
See full preprocessing summary:
characteristic sample preprocessor nElementsBefore sumWeightBefore nElementsAfter sumWeightAfter preprocessor#1 nElementsBefore#1 sumWeightBefore#1 nElementsAfter#1 sumWeightAfter#1 preprocessor#2 nElementsBefore#2 sumWeightBefore#2 nElementsAfter#2 sumWeightAfter#2 preprocessor#3 nElementsBefore#3 sumWeightBefore#3 nElementsAfter#3 sumWeightAfter#3 preprocessor#4 nElementsBefore#4 sumWeightBefore#4 nElementsAfter#4 sumWeightAfter#4
VFamilyUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
VFamilyUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
VFamilyUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
VFamilyUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
VFamilyUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
VFamilyUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
VFamilyUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
VFamilyUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
IsotypeUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
IsotypeUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
IsotypeUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
IsotypeUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
IsotypeUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
IsotypeUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
IsotypeUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
IsotypeUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
VSegmentUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
VSegmentUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
VSegmentUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
VSegmentUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
VSegmentUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
VSegmentUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
VSegmentUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
VSegmentUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
JSegmentUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
JSegmentUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
JSegmentUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
JSegmentUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
JSegmentUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
JSegmentUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
JSegmentUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
JSegmentUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
JFamilyUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
JFamilyUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
JFamilyUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
JFamilyUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
JFamilyUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
JFamilyUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
JFamilyUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
JFamilyUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
Charge mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Charge mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Charge mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Charge mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Charge mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Charge mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Charge mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Charge mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Diversity Shannon-Wiener diversity/Normalized Shannon-Wiener index/Efron-Thisted estimate/Chao1 estimate/Observed diversity/Gini index/Inverse Simpson index mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
Hydrophobicity mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Hydrophobicity mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Hydrophobicity mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Hydrophobicity mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Hydrophobicity mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Hydrophobicity mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Hydrophobicity mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Hydrophobicity mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
CDR3 spectratype mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
CDR3 spectratype mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
CDR3 spectratype mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
CDR3 spectratype mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
CDR3 spectratype mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
CDR3 spectratype mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
CDR3 spectratype mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
CDR3 spectratype mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
Surface mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Surface mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Surface mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Surface mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Surface mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Surface mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Surface mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Surface mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
VSpectratypeMean mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
VSpectratypeMean mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
VSpectratypeMean mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
VSpectratypeMean mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
VSpectratypeMean mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
VSpectratypeMean mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
VSpectratypeMean mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
VSpectratypeMean mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
VJFamilyUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
VJFamilyUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
VJFamilyUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
VJFamilyUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
VJFamilyUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
VJFamilyUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
VJFamilyUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
VJFamilyUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
Volume mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Volume mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Volume mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Volume mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Volume mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Volume mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Volume mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Volume mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
Added N, nt mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Added N, nt mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Added N, nt mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Added N, nt mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Added N, nt mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Added N, nt mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Added N, nt mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Added N, nt mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
CDR3 length, nt mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
CDR3 length, nt mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
CDR3 length, nt mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
CDR3 length, nt mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
CDR3 length, nt mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
CDR3 length, nt mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
CDR3 length, nt mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
CDR3 length, nt mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
VJSegmentUsage mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
VJSegmentUsage mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
VJSegmentUsage mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
VJSegmentUsage mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
VJSegmentUsage mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
VJSegmentUsage mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
VJSegmentUsage mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
VJSegmentUsage mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
VSpectratype mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
VSpectratype mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
VSpectratype mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
VSpectratype mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
VSpectratype mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
VSpectratype mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
VSpectratype mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
VSpectratype mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
NDN length, nt mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
NDN length, nt mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
NDN length, nt mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
NDN length, nt mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
NDN length, nt mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
NDN length, nt mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
NDN length, nt mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
NDN length, nt mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
d50 mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 430 70935 9 95826 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 Cumulative top 50.0 184 184695 9 95826
d50 mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 472 77203 7 92309 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 Cumulative top 50.0 169 176296 7 92309
d50 mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 986 150281 17 40473 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 Cumulative top 50.0 349 80901 17 40473
d50 mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 1565 48975 28 26651 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 Cumulative top 50.0 827 52713 28 26651
d50 mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 640 118290 6 46724 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 Cumulative top 50.0 181 89820 6 46724
d50 mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 929 204207 15 50263 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 Cumulative top 50.0 297 100302 15 50263
d50 mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 852 126589 9 31356 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 Cumulative top 50.0 301 62151 9 31356
d50 mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic | Cumulative top 50.0 1866 80930 27 24598 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 Cumulative top 50.0 913 48802 27 24598
Strength mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
Strength mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
Strength mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
Strength mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
Strength mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
Strength mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
Strength mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
Strength mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan
CDR3 length, aa mouse_4_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 430 70935 184 20235 Filter [IGH] 430 70935 205 20263 Filter stops in CDR3, OOF in CDR3 205 20263 184 20235 Downsample by umi automatic 184 20235 184 20235 nan nan nan nan
CDR3 length, aa mouse_3_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 472 77203 169 20235 Filter [IGH] 472 77203 220 29992 Filter stops in CDR3, OOF in CDR3 220 29992 198 29945 Downsample by umi automatic 198 29945 169 20235 nan nan nan nan
CDR3 length, aa mouse_3.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 986 150281 349 20235 Filter [IGH] 986 150281 449 38797 Filter stops in CDR3, OOF in CDR3 449 38797 411 38694 Downsample by umi automatic 411 38694 349 20235 nan nan nan nan
CDR3 length, aa mouse_1.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1565 48975 827 20114 Filter [IGH] 1565 48975 856 20171 Filter stops in CDR3, OOF in CDR3 856 20171 827 20114 Downsample by umi automatic 827 20114 827 20114 nan nan nan nan
CDR3 length, aa mouse_4.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 640 118290 181 20235 Filter [IGH] 640 118290 313 59825 Filter stops in CDR3, OOF in CDR3 313 59825 264 59676 Downsample by umi automatic 264 59676 181 20235 nan nan nan nan
CDR3 length, aa mouse_2_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 929 204207 297 20235 Filter [IGH] 929 204207 389 33070 Filter stops in CDR3, OOF in CDR3 389 33070 354 32987 Downsample by umi automatic 354 32987 297 20235 nan nan nan nan
CDR3 length, aa mouse_1_Cd4Cre.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 852 126589 301 20235 Filter [IGH] 852 126589 425 52971 Filter stops in CDR3, OOF in CDR3 425 52971 376 52897 Downsample by umi automatic 376 52897 301 20235 nan nan nan nan
CDR3 length, aa mouse_2.clns Filter [IGH] | Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic 1866 80930 913 20235 Filter [IGH] 1866 80930 1087 32440 Filter stops in CDR3, OOF in CDR3 1087 32440 1053 32355 Downsample by umi automatic 1053 32355 913 20235 nan nan nan nan

Columns explained:

characteristic
metrics name (ex.IsotypeUsage)
sample
name of the .clns file (ex. mouse_4_Cd4Cre.clns)
preprocessor

the name of the overall preprocessors chain applied to the dataset. Filter[IGH]|Filter stops in CDR3, OOF in CDR3 | Downsample by umi automatic means the data has been subjected to three consecutive preprocessors:

  • Only IGH chains were filtered
  • Non-functional clonotypes containing stop-codons and OOF clones were filltered out and only functional were left
  • Automatic Downsampling function has been applied to normalize sample sizes
nElementsBefore
number of clonotypes before any preprocessing applied (that is in the initial dataset) (ex. 430 clones)
sumWeightBefore
total weight of all clonotypes before any preprocessing applied. The weight may be either number of reads, UMIs or cells, depending on the selected downsampling. In this case it represents the total number of reads that contribute to clonotypes (ex.70935 UMIs)
nElementsAfter
number of clonotypes in the dataset after all preprocessors have been applied (ex.184 clones)
sumWeightAfter
total weight of all clonotypes after all preprocessors have been applied (ex. 20235). Note that not all samples have the same value for sumWeightAfter. Because automatic downsampling was applied, the optimal threshold was evaluated, but some samples can be left out. We can other proceed with the analysis as is, we can also change the --default-downsampling parameter to count-umi-min which will downsample all samples to the smallest number of UMIs among all samples, or we can use --drop-outliers option to filter out samples with lower UMIs numbers then automatically calculated threshold.
preprocessor#i
i-th part of the preprocessing chain (ex. preprocessor#1: Filter [IGH])
nElementsBefore#i
number of clonotypes before i-th preprocessor has been applied (ex. nElementsBefore#1: 430)
sumWeightBefore#i
total weight of all clonotypes before i-th preprocessor has been applied (ex. sumWeightBefore#1: 70935.0)
nElementsAfter#i
number of clonotypes after i-th preprocessor has been applied (ex. nElementsAfter#1: 205)
sumWeightAfter#i
total weight of all clonotypes after i-th preprocessor has been applied (ex. sumWeightAfter#1: 20263.0)

. . .

Various postanalysis tables contain information about each metric computed for each sample. For example, let's have a look inside pa.i.diversity.IGK.tsv. This table contains frequencies for each J segment present in the sample :

sample Observed diversity Shannon-Wiener diversity Normalized Shannon-Wiener index Inverse Simpson index Gini index Chao1 estimate Efron-Thisted estimate d50
mouse_1_Cd4Cre.clns 278 23.4245 0.560411 6.15117 1.16257 551 543 4
mouse_1.clns 655 93.1602 0.699241 30.7634 1.03251 1125.88 1345 15
mouse_2_Cd4Cre.clns 243 25.6253 0.590487 8.38435 1.11927 449.105 459 4
mouse_2.clns 652 61.9764 0.63684 19.1288 1.05228 929.55 1130 10
mouse_3_Cd4Cre.clns 194 37.984 0.690445 21.0011 1.04762 291.533 319 8
mouse_3.clns 291 22.4745 0.548599 5.86987 1.17036 563.5 571 3
mouse_4_Cd4Cre.clns 151 28.3614 0.666702 17.9849 1.0556 352.25 280 7
mouse_4.clns 181 18.7423 0.563775 6.0494 1.16531 277.13 293 4

Graphical output

MiXCR allows to export graphical results in PDF, EPS, PNG and SVG formats using exportPlots command.

For diversity metrics and CDR3 properties MiXCR allows to group data in different ways according to the submitted metadata.tsv and apply various statistical tests for group comparison.

Diversity

We are going to construct a box plot to compare inverse Simpson diversity Index between two groups of mice. That can be easily done with a single command:

mixcr exportPlots diversity \
    --metadata metadata.tsv \
    --chain IGH \
    --plot-type boxplot \
    --metric inverseSimpsonIndex \
    --primary-group genotype \
    pa/individual.json.gz \
    figs/diversity.pdf

Arguments explained:

--metadata
metadata.tsv is the name of metadata file.
--plot-type
boxplot is the type of plot to generate. See mixcr exportPlots for other options.
--metric:
inverseSimpsonIndex is the name of the metric to visualize. See diversity metrics for other options. If not specified multiple plots will be generated for each available diversity metric.
--primary-group
genotype is name of the column with metadata values from metadata.tsv to group samples by.
pa/individual.json.gz
the name of gzipped JSON file with all postanalysis results generated by `mixcr postanalysis individual
V usage

Next lets create a V-usage plot.

mixcr exportPlots vUsage \
    --metadata metadata.tsv \
    --bar-plot \
    --family-usage \
    pa/individual.json.gz \
    figs/vUsage.pdf
--bar-plot
create a bar-plot instead of heatmap
--family-usage
merge V-genes by family

jUsage.IGH.svg

Overlap postanalysis

MiXCR also allows performing an overall overlap analysis using mixcr postanalysis overlap. But here, since there are a lot of samples we want to actually overlap groups of samples. Running the following command will perform pairwise overlap comparison between groups of samples with different tissue and condition values.

mixcr postanalysis overlap \
    --metadata metadata.tsv \
    --default-downsampling count-umi-auto \
    --default-weight-function umi \
    --only-productive \
    --chains IGH \
    --tables pa/postanalysis.overlap.tsv \
    --preproc-tables pa/preproc.overlap.tsv \
    results/*.clns \
    pa/overlap.json.gz

This command will generate a set of files:

#Tsv files for every metric
postanalysis.overlap.F1Index.IGH.tsv
postanalysis.overlap.F2Index.IGH.tsv
postanalysis.overlap.JaccardIndex.IGH.tsv
postanalysis.overlap.PearsonAll.IGH.tsv
postanalysis.overlap.Pearson.IGH.tsv
postanalysis.overlap.RelativeDiversity.IGH.tsv
postanalysis.overlap.SharedClonotypes.IGH.tsv

# summary of applied preprocessors
preproc.overlap.IGH.tsv

# gzipped JSON with all results 
overlap.tissue_condition.json.gz

The tabular output for example for F2 metric will look like:

sample mouse_1_Cd4Cre.clns mouse_1.clns mouse_2_Cd4Cre.clns mouse_2.clns mouse_3_Cd4Cre.clns mouse_3.clns mouse_4_Cd4Cre.clns mouse_4.clns
mouse_1_Cd4Cre.clns 1 0 0.0014425 0.000921906 0.0116618 0 0.010136 0
mouse_1.clns 0 1 0.0107964 0.00309463 0.0144072 0.00317743 0 0.00630132
mouse_2_Cd4Cre.clns 0.0014425 0.0107964 1 0.008379 0.0308547 0.00321066 0.0038623 0
mouse_2.clns 0.000921906 0.00309463 0.008379 1 0.00797904 0.0019743 0 0.000957001
mouse_3_Cd4Cre.clns 0.0116618 0.0144072 0.0308547 0.00797904 1 0.000506397 0.0228225 0
mouse_3.clns 0 0.00317743 0.00321066 0.0019743 0.000506397 1 0 0
mouse_4_Cd4Cre.clns 0.010136 0 0.0038623 0 0.0228225 0 1 0
mouse_4.clns 0 0.00630132 0 0.000957001 0 0 0 1

Every overlap metric can be exported in a graphical format:

mixcr exportPlots overlap \
    --chains IGH \
    --palette density \
    --metric pearson \
    pa/overlap.json.gz \
    figs/overlap.pdf

For list of available parameters see mixcr exportPlots overlap

overlap.pearson.svg

For further details see overlap postanalysis reference.